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Acyl-CoA Dehydrogenase Family, Member 9 Proteins (ACAD9)

ACAD9 encodes a member of the acyl-CoA dehydrogenase family. Additionally we are shipping Acyl-CoA Dehydrogenase Family, Member 9 Antibodies (30) and Acyl-CoA Dehydrogenase Family, Member 9 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACAD9 28976 Q9H845
Rat ACAD9 ACAD9 294973  
Mouse ACAD9 ACAD9 229211 Q8JZN5
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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ACAD9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Acyl-CoA Dehydrogenase Family, Member 9 (ACAD9) Interaction Partners

Human Acyl-CoA Dehydrogenase Family, Member 9 (ACAD9) interaction partners

  1. Case Report: neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules.

  2. In cells where it is strongly expressed, ACAD9 plays a physiological role in fatty acid oxidation.

  3. Our results underscore the importance of the ACAD9 protein in complex I assembly and suggest that the enzymatic activity is a rudiment of the duplication event.

  4. Our data support a new function for ACAD9 in complex I function, making this gene an important new candidate for patients with complex I deficiency, which could be improved by riboflavin treatment.

  5. ACAD9 screening of 120 additional complex I-defective index cases led us to identify two additional unrelated cases and a total of five pathogenic ACAD9 alleles.

  6. Data show that two closely related metabolic enzymes, ACAD9 and VLCAD (show ACADVL Proteins), diverged at the root of the vertebrate lineage to function in two separate mitochondrial metabolic pathways and have clinical implications for the diagnosis of complex I deficiency.

  7. Very high activity of CPT2 (show CPT2 Proteins) and VCLAD, involved in the metabolism of long-chain fatty acids. Fatty acid oxidation may play role in energy generation in placenta, and deficiency in may result in placental dysfunction and gestational complications.

  8. ACAD9 may play a role in the turnover of lipid membrane unsaturated fatty acids that are essential for membrane integrity and structure

  9. acyl-CoA dehydrogenase (show ACADM Proteins) 9 (ACAD 9)was identified as the long-chain ACAD in human embryonic and fetal brain and central nervous tissue, using in situ hybridization as well as enzymatic studies

  10. We now report three cases of ACAD9 deficiency.

Mouse (Murine) Acyl-CoA Dehydrogenase Family, Member 9 (ACAD9) interaction partners

  1. We conclude that disturbed mitochondrial bioenergetics in BAT (show BAAT Proteins) is a critical contributing factor for the cold sensitivity in VLCAD (show ACADVL Proteins) deficiency

Acyl-CoA Dehydrogenase Family, Member 9 (ACAD9) Protein Profile

Protein Summary

This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ACAD9

  • acyl-CoA dehydrogenase family, member 9 (ACAD9)
  • acyl-CoA dehydrogenase family, member 9 (Acad9)
  • acyl-Coenzyme A dehydrogenase family, member 9 (Acad9)
  • 2600017P15Rik protein
  • 4732402K02 protein
  • C630012L17Rik protein
  • NPD002 protein
  • Nyggf2 protein

Protein level used designations for ACAD9

acyl-CoA dehydrogenase family member 9, mitochondrial , acyl-Coenzyme A dehydrogenase family, member 9 , very-long-chain acyl-CoA dehydrogenase VLCAD , ACAD-9 , very-long-chain acyl-CoA dehydrogenase VLCAD homolog

GENE ID SPECIES
28976 Homo sapiens
294973 Rattus norvegicus
229211 Mus musculus
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