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Acyl-CoA Synthetase Long-Chain Family Member 5 Proteins (ACSL5)

The protein encoded by ACSL5 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Additionally we are shipping ACSL5 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACSL5 51703 Q9ULC5
ACSL5 433256 Q8JZR0
ACSL5 94340 O88813
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Top ACSL5 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,886.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ACSL5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Interaction Partners

Human Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) interaction partners

  1. ACSL5 mediates antiproliferative activities via Wnt2B (show WNT2B Proteins) palmitoylation with diminished Wnt (show WNT2 Proteins) activity. The molecular pathway is probably relevant for intestinal homeostasis, overwhelmed by other pathways in carcinogenesis.

  2. Uncoupling of ACSL5 and mitochondrial mortalin (show HSPA9 Proteins) by mutated TP53 (show TP53 Proteins) could be important in colorectal carcinogenesis.

  3. Down-regulation of ACSL5 is associated with colorectal cancer.

  4. Levels of acyl-coenzyme A (show SOAT2 Proteins) synthetase 5 in urothelial cells and corresponding neoplasias reflect cellular differentiation.

  5. High ACSL5 transcript levels associate with systemic lupus erythematosus and apoptosis in Jurkat T lymphocytes and peripheral blood cells

  6. The data strongly indicate that human but not rat acyl-CoA synthetase 5 is sensitive to triacsin C and does not compensate for other triacsin C-sensitive ACSL isoforms.

  7. Increased ACSL5 is associated with Fatty Liver.

  8. expression of ACS5 in the gastric body and the small intestine with metaplasia or heterotopia

  9. ACS5 is a very suitable marker molecule for the detection of villus atrophy in the small intestine.

  10. SREBP-1c-mediated insulin regulation of acyl-CoA synthestase 5 expression indicate that ACS-5 is involved in the anabolic fate of fatty acids.

Mouse (Murine) Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) interaction partners

  1. Acsl5 is a major activator of dietary long chain fatty acids , yet in Acsl5 KO mice residual ACS activity is sufficient for maintaining a normal long chain fatty acids absorption.

  2. Acyl-CoA synthetase 2 has a role in fatty acid internalization and neurite outgrowth

ACSL5 Protein Profile

Protein Summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ACSL5

  • acyl-CoA synthetase long-chain family member 5 (ACSL5)
  • acyl-CoA synthetase long-chain family member 5 (acsl5)
  • acyl-CoA synthetase long-chain family member 5 (LOC100217956)
  • acyl-CoA synthetase long-chain family member 5 (Acsl5)
  • 1700030F05Rik protein
  • ACS2 protein
  • Acs5 protein
  • ACSL5 protein
  • Facl5 protein
  • zgc:92083 protein

Protein level used designations for ACSL5

acyl-CoA synthetase long-chain family member 5 , long-chain-fatty-acid--CoA ligase 5 , acyl-CoA synthetase 5 , long-chain-fatty-acid--CoA ligase 5-like , FACL5 for fatty acid coenzyme A ligase 5 , LACS 5 , fatty acid coenzyme A ligase 5 , fatty-acid-Coenzyme A ligase, long-chain 5 , long-chain acyl-CoA synthetase 5 , long-chain fatty acid coenzyme A ligase 5 , fatty acid Coenzyme A ligase, long chain 5

GENE ID SPECIES
450739 Pan troglodytes
496479 Xenopus (Silurana) tropicalis
100059190 Equus caballus
100082580 Ornithorhynchus anatinus
100217956 Taeniopygia guttata
100379229 Cavia porcellus
100434441 Pongo abelii
100472737 Ailuropoda melanoleuca
100548195 Meleagris gallopavo
100561703 Anolis carolinensis
100587448 Nomascus leucogenys
51703 Homo sapiens
433256 Mus musculus
94340 Rattus norvegicus
447860 Danio rerio
423896 Gallus gallus
477820 Canis lupus familiaris
100157521 Sus scrofa
514159 Bos taurus
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