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anti-Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2) Antibodies

ACSS2 encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. Additionally we are shipping ACSS2 Kits (8) and ACSS2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACSS2 55902 Q9NR19
ACSS2 60525 Q9QXG4
ACSS2 311569  
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Top anti-ACSS2 Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ACSS2 Antibody (N-term) in K562 cell line lysates (35 µg/lane).ACSS2 (arrow) was detected using the purified Pab. Western blot analysis of ACSS2 Antibody (N-term) in mouse liver tissue lysates (35 µg/lane). ACSS2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB ACSS2 Antibody (Center) (ABIN657155) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the ACSS2 antibody detected the ACSS2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ACSS2 Antibody (N-term) (ABIN653559) in K562 cell line lysates (35 µg/lane).ACSS2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ACSS2 Antibody (N-term) (ABIN653559) in mouse liver tissue lysates (35 µg/lane). ACSS2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSS2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSS2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSS2. Immunohistochemical staining of paraffin-embedded Human tonsil using anti-ACSS2 mouse monoclonal antibody. (ABIN2455072) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC204260 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-ACSS2 antibody (ABIN2455075), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSS2. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ACSS2 AntibodyTitration: 1.0 µg/mL  Positive Control: HT1080 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

ACSS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-ACSS2 Antibodies

  1. Human Polyclonal ACSS2 Primary Antibody for EIA, WB - ABIN950257 : Yun, Bang, Kim, Park, Kim, Lee: The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma. in Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009 (PubMed)
    Show all 3 references for ABIN950257

  2. Human Polyclonal ACSS2 Primary Antibody for IHC (p), WB - ABIN657155 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)

More Antibodies against ACSS2 Interaction Partners

Human Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2) interaction partners

  1. Loss of ACSS2 expression is associated with with gastric cancer.

  2. Study revealed that the activity of acetyl-CoA synthetase 2 (show ACSS1 Antibodies) (ACSS2) contributes to cancer cell growth under low-oxygen and lipid-depleted conditions.

  3. Observations suggest that ACSS2 is expressed to a significant extent in particular tumor types, including triple-negative breast cancers.

  4. Study shows that ACSS2 is upregulated in the human orthotopic tumor and primary human tumors, as well as a murine glioma model; the tumors do not oxidize [U-(13)C]glutamine (show GFPT1 Antibodies). In vivo oxidation of [1,2-(13)C]acetate was validated in brain tumor patients and was correlated with expression of acetyl-CoA synthetase enzyme 2, ACSS2.

  5. During hypoxia, ACSS2 modulates interactions (show LPCAT2 Antibodies)of the acetylase/coactivator CBP with the stress-responsive transcription fa (show CREBBP Antibodies)ctor, HIF-2. These int (show CREBBP Antibodies)eractions include acetylation of HIF-2 by CBP as well as stable HIF-2/CBP comple (show EPO Antibodies)x formation, both of which are required for maximal HIF-2 signaling. Thus, ACSS2 links changes in metabolism that occur during stress with activation of a selective nuclear signaling pathway.

  6. Ritonavir (at 100 mg once daily and 100 mg twice daily significantly down-regulated acyl-CoA synthetase short-chain family member 2 in 20 healthy individuals.

  7. Because the activity of a bacterial ortholog of AceCS2 (show ACSS1 Antibodies), called ACS (show PLA2G15 Antibodies), is controlled via deacetylation by a bacterial sirtuin (show SIRT1 Antibodies) protein, our observation highlights the conservation of a metabolic regulatory pathway from bacteria to humans

  8. The patterns of (18)F-FDG (show SMUG1 Antibodies) and (11)C-acetate uptake seemed to complement each other in both human HCC (show FAM126A Antibodies) and HCC (show FAM126A Antibodies) cell lines.

Mouse (Murine) Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2) interaction partners

  1. Study revealed that the activity of acetyl-CoA synthetase 2 (show ACSS1 Antibodies) (ACSS2) contributes to cancer cell growth under low-oxygen and lipid-depleted conditions.

  2. Study reports evidence that the nucleocytosolic ACSS2 enzyme is of critical importance for mammalian cells to utilize acetate as a source of acetyl-CoA (show LPCAT1 Antibodies), and that mice lacking this enzyme exhibit a substantial reduction in tumor burden in two genetic models of liver cancer.

  3. Study shows that ACSS2 is upregulated in the human orthotopic tumor and primary human tumors, as well as a murine glioma model; the tumors do not oxidize [U-(13)C]glutamine (show GFPT1 Antibodies). In vivo oxidation of [1,2-(13)C]acetate was validated in brain tumor patients and was correlated with expression of acetyl-CoA synthetase (show Acsl1 Antibodies) enzyme 2, ACSS2.

  4. Acss2 generates a specific pool of acetyl CoA (show LPCAT1 Antibodies) during hypoxia that modulates interactions of the acetylase/coactivator Cbp (show CREBBP Antibodies) (also known as Crebbp (show CREBBP Antibodies)) with the stress-responsive transcription factor, Hif-2. Because erythropoietin (show EPO Antibodies) is a Hif-2 target gene, red blood cell production in mice is also regulated by Acss2. Recovery from anemia is accelerated by administering acetate, although this requires the presence of Acss2.

  5. Acetyl CoA synthetase-1 (AceCS1) is mainly expressed in oligodendrocytes in the rat brain. It is located both in cytosol and nucleus of mammalian cells.

  6. Expression of cytosolic acetyl-CoA synthetase gene in mice is developmentally regulated

  7. ACSS2 might play a buffering role in tumor acetyl-CoA (show LPCAT1 Antibodies)/acetate metabolism

ACSS2 Antigen Profile

Protein Summary

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ACSS2

  • acyl-CoA synthetase short-chain family member 2 (ACSS2) antibody
  • acyl-CoA synthetase short-chain family member 2 (acss2) antibody
  • acyl-CoA synthetase short-chain family member 2 (Acss2) antibody
  • 1110017C11Rik antibody
  • ACAS antibody
  • Acas1 antibody
  • Acas2 antibody
  • ACECS antibody
  • AceCS1 antibody
  • ACS antibody
  • Acs1 antibody
  • ACSA antibody
  • dJ1161H23.1 antibody
  • wu:fa04c03 antibody
  • wu:fj80b06 antibody
  • wu:fj80h04 antibody
  • zgc:92200 antibody

Protein level used designations for ACSS2

acyl-CoA synthetase short-chain family member 2 , acetyl-coenzyme A synthetase, cytoplasmic , acetyl-coenzyme A synthetase, cytoplasmic-like , fa04c03 , fj80b06 , fj80h04 , acetyl-CoA synthetase 2 , acetate thiokinase , acetate-CoA ligase , acetyl-Coenzyme A synthetase 2 (ADP forming) , acyl-activating enzyme , cytoplasmic acetyl-coenzyme A synthetase , ACS , aceCS , acetate--CoA ligase , acetyl-CoA synthetase 1 , acetyl-Coenzyme A synthetase 1 (AMP forming) , acetyl-Coenzyme A synthetase 2 (AMP forming)

GENE ID SPECIES
477205 Canis lupus familiaris
506459 Bos taurus
100032395 Monodelphis domestica
100054562 Equus caballus
100179555 Ciona intestinalis
100211402 Hydra magnipapillata
100224916 Taeniopygia guttata
100455504 Pongo abelii
100481825 Ailuropoda melanoleuca
419158 Gallus gallus
436914 Danio rerio
458441 Pan troglodytes
706703 Macaca mulatta
780456 Ovis aries
100153866 Sus scrofa
100346003 Oryctolagus cuniculus
100411267 Callithrix jacchus
100542964 Meleagris gallopavo
100604921 Nomascus leucogenys
55902 Homo sapiens
60525 Mus musculus
311569 Rattus norvegicus
Selected quality suppliers for anti-ACSS2 (ACSS2) Antibodies
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