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ACOT13 encodes a member of the thioesterase superfamily. Additionally we are shipping Acyl-CoA Thioesterase 13 Antibodies (65) and Acyl-CoA Thioesterase 13 Proteins (16) and many more products for this protein.
THEM2 protein from zebrafish (fTHEM2) was expressed in Escherichia coli and purified by Ni-affinity and gel-filtration chromatography. fTHEM2 crystals were obtained using the sitting-drop vapour-diffusion method with PEG 10 (show PEG10 ELISA Kits) 000 as precipitant.
Markers in DYX2 (show KIAA0319 ELISA Kits) genes KIAA0319 (show KIAA0319 ELISA Kits) and FAM65B (show FAM65B ELISA Kits) were associated with cortical thickness in the left developing orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 (show KIAA0319 ELISA Kits) and ACOT13 were suggestively associated with overall fractional anisotropy and left pars (show EPRS ELISA Kits) opercularis cortical thickness, respectively.
study failed to show any association of THEM2 SNPs with developmental dyslexia in an Indian population.
The results of this study confirmed that both FOXP2 (show FOXP2 ELISA Kits) and KIAA0319 (show KIAA0319 ELISA Kits)/TTRAP (show TDP2 ELISA Kits)/THEM2 genes play an important role in human language development, but probably through different cerebral pathways.
analysis of human thioesterase superfamily member 2 crystal structure
Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2) and the homeodomain transcription factor Pax3 (paired box gene 3 (show PAX3 ELISA Kits)), respectively, as PC-TP (show PCTP ELISA Kits)-interacting proteins.
The physiological role of hTHEM2 involves catalysis of the hydrolysis of cytosolic medium-to-long-chain acyl-CoA (show GNPAT ELISA Kits) thioesters.
These findings reveal a primary role for Them2 in promoting mitochondrial oxidation of fatty acids and glucose in the liver.
PC-TP (show PCTP ELISA Kits)-THEM2 complex reduces phosphorylation and stability of IRS2 (show IRS2 ELISA Kits) and increases stability of the TSC1 (show TSC1 ELISA Kits)-TSC2 (show TSC2 ELISA Kits) complex
Them2 functions in brown adipose tissue to suppress adaptive increases in energy expenditure.
This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.
acyl-CoA thioesterase 13
, acyl-coenzyme A thioesterase 13
, thioesterase superfamily member 2
, hypothalamus protein HT012