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ACOT13 encodes a member of the thioesterase superfamily. Additionally we are shipping Acyl-CoA Thioesterase 13 Antibodies (57) and Acyl-CoA Thioesterase 13 Kits (4) and many more products for this protein.
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Human ACOT13 Protein expressed in Escherichia coli (E. coli) - ABIN667825
Kanno, Wu, Agate, Fanelli, Wagle, Scapa, Ukomadu, Cohen: Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2. in The Journal of biological chemistry 2007
Show all 2 references for ABIN667825
THEM2 protein from zebrafish (fTHEM2) was expressed in Escherichia coli and purified by Ni-affinity and gel-filtration chromatography. fTHEM2 crystals were obtained using the sitting-drop vapour-diffusion method with PEG 10 (show PEG10 Proteins) 000 as precipitant.
study failed to show any association of THEM2 SNPs with developmental dyslexia in an Indian population.
The results of this study confirmed that both FOXP2 (show FOXP2 Proteins) and KIAA0319 (show KIAA0319 Proteins)/TTRAP (show TDP2 Proteins)/THEM2 genes play an important role in human language development, but probably through different cerebral pathways.
analysis of human thioesterase superfamily member 2 crystal structure
Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2) and the homeodomain transcription factor Pax3 (paired box gene 3 (show PAX3 Proteins)), respectively, as PC-TP (show PCTP Proteins)-interacting proteins.
The physiological role of hTHEM2 involves catalysis of the hydrolysis of cytosolic medium-to-long-chain acyl-CoA (show GNPAT Proteins) thioesters.
These findings reveal a primary role for Them2 in promoting mitochondrial oxidation of fatty acids and glucose in the liver.
PC-TP-THEM2 complex reduces phosphorylation and stability of IRS2 and increases stability of the TSC1-TSC2 complex
Them2 functions in brown adipose tissue to suppress adaptive increases in energy expenditure.
This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.
acyl-CoA thioesterase 13
, acyl-coenzyme A thioesterase 13
, thioesterase superfamily member 2
, hypothalamus protein HT012