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The protein encoded by AGK is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. Additionally we are shipping Acylglycerol Kinase Antibodies (29) and Acylglycerol Kinase Kits (4) and many more products for this protein.
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AGK promotes the proliferation and cell cycle progression of oral squamous cell carcinoma.
miR (show MLXIP Proteins)-194 could reduce the phosphoinositide 3-kinase (PI3K (show PIK3CA Proteins))/AKT (show AKT1 Proteins)/FoxO3a (show FOXO3 Proteins) signaling pathway by suppressing acylglycerol kinase (AGK) directly.
findings provide new evidence that AGK plays an important role in promoting angiogenesis and providing resistance to apoptosis in hepatocellular carcinoma
compare our findings to those in 21 previously reported AGK mutation-positive Sengers patients, confirming that Sengers syndrome is a clinically recognisable disorder of mitochondrial energy metabolism
AGK promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 (show FOXO1 Proteins).
Our findings suggest that ATX-AGK-LPA signaling axis might be an important player in the development and progression of diabetic retinopathy.
AGK expression was significantly correlated with JAK2 (show JAK2 Proteins)/STAT3 (show STAT3 Proteins) hyperactivation in esophageal squamous cell carcinoma, as well as in lung and breast cancer.
study reports 2 families with Sengers syndrome and mutations in the acylglycerol kinase gene; 1 proband had abnormal mitochondria with citrate synthase (show CS Proteins) crystals, associated with high citrate synthase (show CS Proteins) activity; these pedigrees confirm that mutation of AGK is responsible for the severe neonatal presentation of Sengers syndrome
This is the first mutation in AGK gene to be implicated in the development of isolated cataract.
Lack of the AGK causes Sengers syndrome
The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10.
, acylglycerol kinase, mitochondrial-like
, acylglycerol kinase, mitochondrial
, multi-substrate lipid kinase
, multiple substrate lipid kinase