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As part of AP-5, a probable fifth adapter protein complex it may be involved in endosomal transport.. Additionally we are shipping and and many more products for this protein.
HIV-2 particle release was dependent on the adaptor protein complex AP-3 and the newly identified AP-5 complex, but much less so on AP-1 (show FOSB ELISA Kits).
We propose AP-5, SPG15 (show ZFYVE26 ELISA Kits), SPG11 (show SPG11 ELISA Kits) form a coat-like complex, with AP-5 involved in protein sorting, SPG15 (show ZFYVE26 ELISA Kits) facilitating docking of the coat onto membranes by interacting with PI3P via its FYVE domain, and SPG11 (show SPG11 ELISA Kits) (possibly together with SPG15 (show ZFYVE26 ELISA Kits)) forming a scaffold.
AP-5 is an evolutionarily ancient complex, which is involved in endosomal sorting, and which has links with hereditary spastic paraplegia.
As part of AP-5, a probable fifth adapter protein complex it may be involved in endosomal transport.
AP-5 complex subunit beta
, AP-5 complex subunit beta-1
, adapter-related protein complex 5 beta subunit