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Ap4m1 encodes a subunit of the heterotetrameric AP-4 complex. Additionally we are shipping Adaptor-Related Protein Complex 4, mu 1 Subunit Antibodies (54) and Adaptor-Related Protein Complex 4, mu 1 Subunit Kits (12) and many more products for this protein.
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analysis of the AP4M1 mutation associated with aggressive behavior in addition to mild dysmorphic features, intellectual disability, spastic paraparesis and reduced head circumference [case report]
Results show that AP-4 (show REPIN1 Proteins) can bind different types of cytosolic signals known to mediate basolateral transport in epithelial cells. Depletion of mu 4 results in the mis (show AMH Proteins)-sorting of several proteins in epithelial cells.
AP-4 (show REPIN1 Proteins) protein complex is involved in the regulation of somatodendritic-specific distribution of its cargo proteins including AMPA (show GRIA3 Proteins) receptors.
In all five patients with autosomal-recessive type of tetraplegic cerebral palsy with mental retardation, a donor splice site pathogenic mutation in intron 14 of the AP4M1 gene (c.1137+1G-->T), was identified.
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.
adaptor-related protein complex 4, mu 1 subunit
, AP-4 complex subunit mu-1
, AP-4 complex subunit mu-1-like
, adapter-related protein complex 4 mu-1 subunit
, adaptor-related protein complex AP-4 mu4 subunit
, mu subunit of AP-4
, mu-adaptin-related protein 2
, mu-adaptin-related protein-2
, AP-4 adapter complex mu subunit
, adaptor-related protein complex AP-4, mu 1