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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Additionally we are shipping alpha Adducin Proteins (4) and alpha Adducin Kits (2) and many more products for this protein.
Showing 10 out of 144 products:
Human Monoclonal alpha Adducin Primary Antibody for IF, IHC - ABIN658927
Schuur, van Swieten, Schol-Gelok, Ikram, Vernooij, Liu, Isaacs, de Boer, de Koning, Niessen, Vrooman, Oostra, van der Lugt, Breteler, van Duijn: Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population. in Journal of neurology, neurosurgery, and psychiatry 2010
Show all 5 references for ABIN658927
Human Monoclonal alpha Adducin Primary Antibody for IF, IHC - ABIN658928
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
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Human Monoclonal alpha Adducin Primary Antibody for WB - ABIN393590
Irvin, Lynch, Kabagambe, Tiwari, Barzilay, Eckfeldt, Boerwinkle, Davis, Ford, Arnett: Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. in Journal of hypertension 2010
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Human Polyclonal alpha Adducin Primary Antibody for IF, IHC (p) - ABIN196918
Pariser, Herradon, Ezquerra, Perez-Pinera, Deuel: Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C. in Proceedings of the National Academy of Sciences of the United States of America 2005
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Human Polyclonal alpha Adducin Primary Antibody for IF, IHC (p) - ABIN197406
Barkalow, Italiano, Chou, Matsuoka, Bennett, Hartwig: Alpha-adducin dissociates from F-actin and spectrin during platelet activation. in The Journal of cell biology 2003
Show all 2 references for ABIN197406
This indicates that ADD1 G460W polymorphism could be an important factor in the pathophysiology of tinnitus.
Study shows that ADD1-rs4963 conferred susceptibility to colorectal cancer (CRC (show CALR Antibodies)) suggesting an association between ADD1 and CRC (show CALR Antibodies) risk.
The T allele of ADD1 is associated with essential hypertension in Asians.
study of potential effects of interaction between DNA methylation (show HELLS Antibodies) of ADD1 promoter and ADD1 tagSNPs and environmental factors on essential hypertension (EH); results indicate ADD1 SNP rs4961 has a protective role in development of EH; interactions between alcohol consumption and DNA methylation (show HELLS Antibodies) of ADD1 gene promoter have a significant role in modifying EH susceptibility
There were significant differences between the control group and pediatric hypertensive group in terms of ACE (show ACE Antibodies) I/D (P<0.05) and AGT (show AGXT Antibodies) M235T (P<0.05) polymorphisms, but there were no differences in ADD Gly460Trp (P>0.05) polymorphism.
A significant association was found between ADD1 gene G614T polymorphism and essential hypertension in Chinese patients. Further studies need to be done to confirm these findings in a large sample.
When alpha-adducin complexes with sodium potassium ATPase (show DNAH8 Antibodies) in astrocytes, non-cell autonomous neurodegeneration is triggered.
Phosphorylation of ADD1 at Ser12 and Ser355 by cyclin-dependent kinase 1 (show CDK1 Antibodies) enables ADD1 to bind to myosin-X (Myo10 (show MYO10 Antibodies)).
Fnnctional polymorphism in the phosphorylation site of ADD1 (rs4963) may influence the susceptibility of non-cardia gastric cancer.
concentration of AST was inversely correlated with ADD1 CpG2 (show SYNE1 Antibodies)-5 methylation levels in female controls. These observations may bring new hints to elaborate the pathogenesis of essential hypertension
The two cereal dietary fibers potently decreased protein expressions of sterol regulatory element binding protein-1 (show SREBF1 Antibodies) and key factors involved in lipogenesis
SREBP-1 (show SREBF1 Antibodies) acts as a positive regulator of Sfrp2 (show SFRP2 Antibodies) transcription in chondrogenic cells.
regulatory mechanism by which insulin (show INS Antibodies) inhibits cardiac UCP3 (show UCP3 Antibodies) expression through activation of the lipogenic factor SREBP-1 (show SREBF1 Antibodies).
Taken together, our results suggest that an NCE-box within the clusterin (show CLU Antibodies) promoter is necessary for insulin (show INS Antibodies)-stimulated hepatic expression of clusterin (show CLU Antibodies) via SREBP-1c (show SREBF1 Antibodies).
both Smad3 (show SMAD3 Antibodies) and SREBP-1a activation cooperatively regulate TGFbeta (show TGFB1 Antibodies) transcriptional responses.
Endoplasmic reticulum stress and SREBP-1 (show SREBF1 Antibodies)-dependent effects were induced in glomeruli of angiotensin II-infused mice.
Data show that knock-in (KI) mice in which a human miR (show MLXIP Antibodies)-33b is inserted within sterol regulatory element-binding protein 1 (Srebf1 (show SREBF1 Antibodies)) intron had reduced HDL (show HSD11B1 Antibodies) cholesterol (HDL (show HSD11B1 Antibodies)-C).
CREB regulated transcription coactivator 2 (CRTC2 (show CRTC2 Antibodies)) functions as a mediator of mTOR (show FRAP1 Antibodies) signalling to modulate COPII-dependent SREBP1 (show SREBF1 Antibodies) processing
Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c (show SREBF1 Antibodies) activity.
Hepatic genes expression profiles demonstrated that LBP (show LBP Antibodies) can activate the phosphorylation of AMPK (show PRKAA1 Antibodies), suppress nuclear expression of SREBP-1c (show SREBF1 Antibodies), and decrease protein and mRNA expression of lipogenic genes in vivo or in vitro
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms\; however, not all variants have been fully described.
adducin 1 (alpha)
, adducin 2 (beta)
, erythrocyte adducin alpha subunit
, erythrocyte adducin subunit alpha
, adipocyte determination- and differentiation-dependent factor 1
, sterol regulatory element-binding protein 1