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Adenine Phosphoribosyltransferase Proteins (APRT)

Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. Additionally we are shipping Adenine Phosphoribosyltransferase Antibodies (79) and Adenine Phosphoribosyltransferase Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APRT 292072 P36972
APRT 11821 P08030
APRT 353 P07741
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Top Adenine Phosphoribosyltransferase Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$322.14
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$2,420.00
Details
Yeast Stochomys longicaudatus His tag   1 mg Log in to see 56 to 66 Days
$2,420.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,420.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,420.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 3 to 4 Days
$2,524.50
Details

APRT Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human , ,
, ,

More Proteins for Adenine Phosphoribosyltransferase (APRT) Interaction Partners

Mouse (Murine) Adenine Phosphoribosyltransferase (APRT) interaction partners

  1. LOH on nonselected chromosomes was infrequent in Aprt mutants exhibiting intragenic events or mitotic recombination for chromosome 8

  2. Data shsow that despite continuous selection for expression of the reactivated Aprt alleles, exceptionally high spontaneous re-silencing frequencies were observed.

  3. silencing of mouse Aprt is a gradual process in the differentiated cells

Human Adenine Phosphoribosyltransferase (APRT) interaction partners

  1. A long TA repeat in the promoter region of IL28B (show IL28B Proteins) was associated with spontaneous HCV clearance.

  2. A new mutation, p.Gln147X, in APRT gene, was found in a patient with adenine phosphoribosyltransferase deficiency.

  3. Case study of 2 year old Japanese boy with APRT deficiency. Genetic analysis showed compound heterozygote APRT*J and missense mutation L33P. APRT deficiency should be suspected in patients with radiolucent kidney stones and urinary 2,8-DHA crystals.

  4. kinetic, regulatory and thermostability properties of APRT from erythrocytes of HGPRT (show HPRT1 Proteins) deficient patients

  5. two novel mutations, G133D and V84M, were found in the APRT gene in Japanese patients with APRT deficiency

  6. APRT assay in a sample of patient hemolysate showed no detectable activity of the enzyme (25.56+/-9.55 U/L red blood cells in control healthy subjects).

  7. The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP are reported.

Adenine Phosphoribosyltransferase (APRT) Protein Profile

Protein Summary

Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with APRT

  • adenine phosphoribosyltransferase (CND05020)
  • adenine phosphoribosyltransferase (Tb927.7.1790)
  • adenine phosphoribosyltransferase (Tb927.7.1780)
  • adenine phosphoribosyltransferase (Arnit_0941)
  • adenine phosphoribosyltransferase (Saut_1231)
  • adenine phosphoribosyltransferase (Fbal_1180)
  • adenine phosphoribosyltransferase (PH1691)
  • adenine phosphoribosyltransferase (PF1735)
  • adenine phosphoribosyltransferase (PAB2035)
  • adenine phosphoribosyl transferase (Aprt)
  • adenine phosphoribosyltransferase (APRT)
  • AMP protein
  • APRTD protein
  • C85684 protein
  • Tb07.43M14.180 protein
  • Tb07.43M14.200 protein

Protein level used designations for APRT

adenine phosphoribosyltransferase , AMP diphosphorylase , AMP pyrophosphorylase , transphosphoribosidase

GENE ID SPECIES
3257455 Cryptococcus neoformans var. neoformans JEC21
3658386 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3658391 Trypanosoma brucei brucei strain 927/4 GUTat10.1
9171098 Arcobacter nitrofigilis DSM 7299
9758775 Sulfurimonas autotrophica DSM 16294
9769940 Ferrimonas balearica DSM 9799
1442536 Pyrococcus horikoshii OT3
1469612 Pyrococcus furiosus DSM 3638
1495379 Pyrococcus abyssi GE5
292072 Rattus norvegicus
11821 Mus musculus
353 Homo sapiens
479615 Canis lupus familiaris
519017 Bos taurus
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