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ADA encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Additionally we are shipping ADA Kits (40) and ADA Proteins (15) and many more products for this protein.
Showing 10 out of 141 products:
Human Monoclonal ADA Primary Antibody for WB - ABIN396441
Ri, Ohno, Furutani, Furutani, Tsukahara, Hagita, Haruyama, Nakamura, Yamamoto, Matsuoka: An indication for correlation between the serum ADA level and gastric cancer risk. in Anticancer research 2010
Show all 5 references for ABIN396441
Human Polyclonal ADA Primary Antibody for EIA, WB - ABIN950276
Gloria-Bottini, Banci, Saccucci, Papetti, Neri, Pietroiusti, Magrini, Bottini: The interaction of ACP1, ADA1, diabetes and gender in coronary artery disease. in The American journal of the medical sciences 2010
Show all 3 references for ABIN950276
Cow (Bovine) Polyclonal ADA Primary Antibody for WB - ABIN2784609
Cassani, Mirolo, Cattaneo, Benninghoff, Hershfield, Carlucci, Tabucchi, Bordignon, Roncarolo, Aiuti: Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. in Blood 2008
The effects of increased adenosine in vivo by mutating the main Drosophila adenosine deaminase-related growth factor (ADGF-A), was studied.
findings show that a null mutation in ADGF-A leads to dramatically increased levels of adenosine & deoxyadenosine in the larval hemolymph; this increase leads to larval death associated with the disintegration of fat body & development of melanotic tumors
Crystal structure of CD26/dipeptidyl-peptidase IV (show DPP4 Antibodies) in complex with adenosine deaminase
the transition-state structures of PfADA, HsADA, and bovine ADA (BtADA) solved using competitive kinetic isotope effects (KIE) and density functional calculations
This is the first report that an inhibitor molecule (EHNA) with a nucleoside framework binds to the open form of ADA and the first observation of conformational change of ADA in the crystalline state.
Data demonstrate that dipeptidyl peptidase II (show DPP7 Antibodies) can form a complex with adenosine deaminase, but with one order of magnitude higher dissociation constant than that of DPPIV (show DPP4 Antibodies).
ADA and ADK (show ADK Antibodies) are involved in glioma progression; increased ADA and ADK (show ADK Antibodies) levels in peritumoral tissues may be associated with epilepsy in glioma patients.
In autologous cocultures of T cells with HIV-1-pulsed dendritic cells, adenosine deaminase decreased HIV-1-induced CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(hi) FOXP3 (show FOXP3 Antibodies)(+) cells and enhanced the HIV-1-specific CD4 (show CD4 Antibodies)(+) responder T cells.
ADA6, PTPN22 (show PTPN22 Antibodies) and ACP1 (show ACP1 Antibodies) are involved in immune reactions: since endometriosis has an autoimmune component.
Pleural ADA activity is an accurate test for the diagnosis of tuberculous pleural effusions.
Serum ADA levels were increased in secondary hemophagocytic lymphohistiocytosis suggesting a partial role of activated T-cell response in the disease pathophysiology.
increase in the salivary ADA and DPP-IV (show DPP4 Antibodies) activities as well as in the lipid peroxidation could be related of the regulation to various aspects of adipose tissue function and inflammatory obesity
Multiplex PCR and thoracoscopy are useful investigations in the diagnostic work-up of pleural effusions complicating CKD while the sensitivity and/or specificity of ADA and 65 kDa gene PCR is poor
the diagnostic utility of pfADA in a low mTB (show NCAPG2 Antibodies) incidence area
activity of ADA isoenzymes and distribution of ADA1 (show TADA1 Antibodies) G22 A genotypes were different among fertile and infertile men and more likely the GA genotype, which had lower ADA1 (show TADA1 Antibodies) activity and was higher in fertile men is a protective factor against infertility.
ADA rs73598374-A carriers showed lower telomerase activity and shorter leukocyte telomere length.
Pulmonary alveolar proteinosis in adenosine deaminase-deficient mice
Dietary regulation of adenosine deaminase activity in stomach, small intestine and spleen of mice
Data indicate that untreated murine adenosine deaminase ADA(-/-) Tregs show alterations in the plasma membrane CD39 (show ENTPD1 Antibodies)/CD73. ectonucleotidase machinery and limited suppressive activity via extracellular adenosine.
ADA is upregulated in NOD dendritic cells, which results in their exuberant and spontaneous activation, which triggers autoimmune T cell activation.
The catalytic mechanism of Mus (show TRPV6 Antibodies) musculus adenosine deaminase (ADA) has been studied by quantum mechanics and two-layered ONIOM calculations
Adenosine deaminase is necessary but not sufficient to confer puromycin aminonucleoside sensitivity to podocytes.
adenosine deaminase deficient results in deoxy-ATP accumulation and leads to reduced thymic T cell production
Transactivation by a duodenum-specific enhancer requires functional GATA4 (show GATA4 Antibodies) binding sites
ADA-deficient B cells exhibit a higher propensity to undergo B cell receptor-mediated apoptosis than their wild-type counterparts, and suggest a role for ADA in the survival of cells during antigen-dependent responses.
This study provides a basis for investigating the folding kinetics of murine ADA and folding mechanisms of (beta/alpha)8-barrel proteins using 19F NMR sepctroscopy.
after the immunotherapy, the rabbits showed an increase in the E-ADA activity when compared with control (78.62%), contributing for the change in the immune response.
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
, adenosine deaminase
, adenosine deaminase-related growth factor A
, adenosine aminohydrolase