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Adenosine Kinase Proteins (ADK)

ADK an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Additionally we are shipping ADK Antibodies (87) and ADK Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADK 132 P55263
ADK 11534 P55264
Rat ADK ADK 25368 Q64640
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Top ADK Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$732.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Fungus His tag   1 mg Log in to see 56 to 66 Days
$2,933.33
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$2,986.50
Details
Yeast Toxoplasma gondii His tag   1 mg Log in to see 56 to 66 Days
$2,992.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$364.64
Details

ADK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Top referenced ADK Proteins

  1. Human ADK Protein expressed in Escherichia coli (E. coli) - ABIN667133 : Chakraborty, Das, Datta, Sen, Bhattacharyya, Mandal, Datta: A single-domain cyclophilin from Leishmania donovani reactivates soluble aggregates of adenosine kinase by isomerase-independent chaperone function. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN667133

  2. Human ADK Protein expressed in Baculovirus infected Insect Cells - ABIN2005495 : Kuettel, Greenwald, Kostrewa, Ahmed, Scapozza, Perozzo: Crystal structures of T. b. rhodesiense adenosine kinase complexed with inhibitor and activator: implications for catalysis and hyperactivation. in PLoS neglected tropical diseases 2011 (PubMed)
    Show all 2 references for ABIN2005495

More Proteins for Adenosine Kinase (ADK) Interaction Partners

Arabidopsis thaliana Adenosine Kinase (ADK) interaction partners

  1. Adenosine kinase contributes to cytokinin homeostasis

  2. Increased cytokinin-responsive promoter activity in Arabidopsis plant tissue may therefore be a consequence of an ADK/AL2/C2 interaction.

Human Adenosine Kinase (ADK) interaction partners

  1. ADA (show ADA Proteins) and ADK are involved in glioma progression; increased ADA (show ADA Proteins) and ADK levels in peritumoral tissues may be associated with epilepsy in glioma patients.

  2. The results of this study suggest that upregulation of ADK is a common pathologic component of FCDIIB.

  3. These results suggest that upregulation of ADK is a common pathologic hallmark of Rasmussen encephalitis and that ADK might be a target in the treatment of epilepsy associated with Rasmussen encephalitis.

  4. Data show that we a significantly higher expression of ADK in the peritumoral infiltrated tissue of patients with epilepsy than in patients without epilepsy.

  5. The results of this study suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of temporal lobe epilepsy.

  6. The cytoplasmic isoform of adenosine kinase is sufficient to alter sleep physiology. ADK might orchestrate neurotransmitter pathways involved in the generation of electroencephlogram oscillations and regulation of sleep.

  7. The catalytic properties, gene expression and protein levels of certain proteins involved in mitochondrial ATP synthesis, such as F1F0-ATPase, ANT and AK, in human skin fibroblasts with trisomic karyotype, compared them with euploid fibroblasts.

  8. Equilibrative nucleoside transporters (hENT1, hENT2) together with adenosine kinase and 5'-nucleotidase (show NT5E Proteins) play a crucial role in the regulation of CFTR (show CFTR Proteins) through an adenosine-dependent pathway in human airway epithelia.

  9. role for HIF-1alpha (show HIF1A Proteins) in transcriptional repression of AK in hypoxia

  10. adenosine kinase gene expression was significantly higher in cancer than in normal-appearing tissue, in line with our previous measurements of adenosine kinase enzyme activities in colorectal tumor samples

Mouse (Murine) Adenosine Kinase (ADK) interaction partners

  1. The findings of this study implicated a glial-neuronal circuit, mediated by Ado (show ADO Proteins), neuronal AdoRA1, and glial AdK that can modulate sleep homeostasis in a manner influenced by glial metabolic state.

  2. We conclude that ADK provides important upstream regulation of adenosine-based homeostatic function of the brain

  3. Adenosine kinase inhibition selectively promotes rodent and porcine islet beta-cell replication

  4. Knockdown of Adk can protect the brain from the effects of a stroke.

  5. a complete absence of ADK led to abnormalities in hepatic adenosine metabolism and to the development of acute, severe neonatal hepatic steatosis.

  6. adenosine kinase inhibition promotes survival of fetal adenosine deaminase (show ADA Proteins)-deficient thymocytes by blocking dATP accumulation

  7. Overexpression of adenosine kinase in discrete parts of the epileptic hippocampus may contribute to the development and progression of seizure activity.

  8. Data report the cloning of two isoforms of adenosine kinase from a mouse brain cDNA library, and the role of these isoenzymes as sustrates for phosphorylation were examined.

  9. transient downregulation of hippocampal ADK after stroke might be a protective mechanism during maturation hippocampal cell loss.

  10. The results of this study confirmed that ADK overexpression could lead to functional concomitant alterations in dopaminergic and glutamatergic functions.

Pig (Porcine) Adenosine Kinase (ADK) interaction partners

  1. Adenosine kinase inhibition selectively promotes rodent and porcine islet beta-cell replication

ADK Protein Profile

Protein Summary

This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Adenosine Kinase Proteins (ADK)

  • adenosine kinase (ADK)
  • adenosine kinase (adk)
  • adenosine kinase (CNN02130)
  • adenosine kinase (AaeL_AAEL001856)
  • adenosine kinase (CMU_026370)
  • ATP:adenosine 5'-phosphotransferase (adk)
  • Adenosine kinase (adk)
  • adenosine kinase (Adk)
  • 2310026J05Rik protein
  • 5033405D03Rik protein
  • adenosine kinase protein
  • adk protein
  • AI255373 protein
  • AI987814 protein
  • Ak protein
  • ATPADK1 protein
  • DDBDRAFT_0186795 protein
  • DDBDRAFT_0230174 protein
  • DDB_0186795 protein
  • DDB_0230174 protein
  • F3G5.4 protein
  • F3G5_4 protein

Protein level used designations for Adenosine Kinase Proteins (ADK)

adenosine kinase , adenosine kinase (short isoform)-like protein , Adenosine kinase , adenosine kinase-like , adenosine 5'-phosphotransferase , Adenosine 5'-phosphotransferase

GENE ID SPECIES
450902 Pan troglodytes
535680 Bos taurus
549452 Xenopus (Silurana) tropicalis
705246 Macaca mulatta
818302 Arabidopsis thaliana
3255448 Cryptococcus neoformans var. neoformans JEC21
5572668 Aedes aegypti
6360172 Burkholderia multivorans ATCC 17616
6995067 Cryptosporidium muris RN66
8625430 Dictyostelium discoideum AX4
100072901 Equus caballus
100306762 Salmo salar
100408817 Callithrix jacchus
100460175 Pongo abelii
100583963 Nomascus leucogenys
132 Homo sapiens
11534 Mus musculus
25368 Rattus norvegicus
783572 Bos taurus
423735 Gallus gallus
479253 Canis lupus familiaris
100154626 Sus scrofa
100736551 Cricetulus griseus
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