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The protein encoded by AMPD2 is important in purine metabolism by converting AMP to IMP. Additionally we are shipping AMPD2 Proteins (6) and AMPD2 Kits (5) and many more products for this protein.
Showing 10 out of 46 products:
Human Monoclonal AMPD2 Primary Antibody for ELISA, WB - ABIN513315
Cicerchi, Li, Kratzer, Garcia, Roncal-Jimenez, Tanabe, Hunter, Rivard, Sautin, Gaucher, Johnson, Lanaspa: Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
Show all 2 references for ABIN513315
Human Polyclonal AMPD2 Primary Antibody for EIA, FACS - ABIN950400
Haas, Sabina: N-terminal extensions of the human AMPD2 polypeptide influence ATP regulation of isoform L. in Biochemical and biophysical research communications 2003
Show all 2 references for ABIN950400
Human Polyclonal AMPD2 Primary Antibody for FACS, IHC (p) - ABIN653063
Mahnke-Zizelman, van den Bergh, Bausch-Jurken, Eddy, Sait, Shows, Sabina: Cloning, sequence and characterization of the human AMPD2 gene: evidence for transcriptional regulation by two closely spaced promoters. in Biochimica et biophysica acta 1996
tofacitinib increases the cellular levels of adenosine, which is known to have anti-inflammatory activity, through the downregulation of AMPD2. This would be a novel functional aspect of tofacitinib.
In human HepG2 cells, AMPD2 activation counterregulates (show PRKAA1 Antibodies)AMPK and increases intracellular glucose production, in association with up-regulatio (show PEPCK Antibodies)n of PEPC (show G6PC Antibodies)K and G6Pc.
Study concluded that AMPD2 as necessary for guanine nucleotide biosynthesis and protein translation and provide evidence that AMP (show APRT Antibodies) deaminase activity is critical during neurogenesis. Patients with mutations in AMPD2 have characteristic brain imaging features of pontocerebellar hypoplasia due to loss of brainstem and cerebellar parenchyma.
N-terminal extensions of the AMPD2 polypeptide influence ATP regulation of isoform L.
This is a first report evidencing the pattern of AMPD (show AMPD1 Antibodies) genes expression in neoplastic human liver.
A novel mouse model of transient hypercholesterolemia with concurrent nephrotic syndrome associated with defective Ampd2 function.
In diabetic mice, AMPD2 activation counterregulates AMPK (show PRKAA1 Antibodies) and increases hepatic glucose production, in association with up-regulation of PEPCK (show PEPCK Antibodies) and G6Pc (show G6PC Antibodies).
The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene.
adenosine monophosphate deaminase 2
, AMP deaminase 2-like
, AMP deaminase 2
, adenosine monophosphate deaminase 2 (isoform L)