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anti-Adenosylhomocysteinase-Like 1 (AHCYL1) Antibodies

The protein encoded by AHCYL1 interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Additionally we are shipping AHCYL1 Proteins (5) and AHCYL1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AHCYL1 10768 O43865
AHCYL1 362013  
AHCYL1 229709 Q80SW1
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Top anti-AHCYL1 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB Host: Rabbit  Target Name: AHCYL1  Sample Tissue: Human Fetal Liver  Antibody Dilution: 1.0 µg/mL Host: Rabbit  Target Name: AHCYL1  Sample Tissue: Human Fetal Lung  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Xenopus laevis Rabbit Un-conjugated WB Hum. Fetal Liver; Host:Rabbit. Target Name:AHCYL1. Sample Tissue:Human Fetal Liver. Antibody Dilution: 1.0ug/ml.; AHCYL1 antibody - N-terminal region in Hum. Fetal Liver cells using Western Blot Hum. Fetal Lung; Host:Rabbit. Target Name:AHCYL1. Sample Tissue:Human Fetal Lung. Antibody Dilution: 1.0ug/ml.; AHCYL1 antibody - N-terminal region in Hum. Fetal Lung cells using Western Blot 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB AHCYL1 monoclonal antibody (M05), clone 5D6 Western Blot analysis of AHCYL1 expression in HeLa . Immunoperoxidase of monoclonal antibody to AHCYL1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.22 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB AHCYL1 monoclonal antibody (M03), clone 1B3. Western Blot analysis of AHCYL1 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated WB AHCYL1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details

AHCYL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Rat (Rattus)


Mouse (Murine)


Top referenced anti-AHCYL1 Antibodies

  1. Chicken Polyclonal AHCYL1 Primary Antibody for WB - ABIN2777769 : Cooper, Key, Carter, Angel, Hart, Kato: Suppression and overexpression of adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) influences zebrafish embryo development: a possible role for AHCYL1 in inositol phospholipid signaling. in The Journal of biological chemistry 2006 (PubMed)

  2. Human Monoclonal AHCYL1 Primary Antibody for IHC (p), ELISA - ABIN564695 : Scicchitano, Dalmas, Boyce, Thomas, Frazier: Protein extraction of formalin-fixed, paraffin-embedded tissue enables robust proteomic profiles by mass spectrometry. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 (PubMed)

  3. Human Polyclonal AHCYL1 Primary Antibody for ELISA, WB - ABIN564694 : Yamaguchi, Ishikawa: IRBIT reduces the apparent affinity for intracellular Mg²? in inhibition of the electrogenic Na?-HCO?? cotransporter NBCe1-B. in Biochemical and biophysical research communications 2012 (PubMed)

More Antibodies against AHCYL1 Interaction Partners

Human Adenosylhomocysteinase-Like 1 (AHCYL1) interaction partners

  1. IRBIT forms signaling complexes with PIPKIalpha and NBCe1 (show SLC4A4 Antibodies)-B, whose activity is regulated by PI(4,5)P2.

  2. Formation of the Ribonucleotide reductase-IRBIT complex is regulated through phosphorylation of IRBIT, and ablation of IRBIT expression in HeLa cells causes imbalanced dNTP pools and altered cell cycle progression.

  3. IRBIT is a master regulator of ion channels and ion transporters. (Review)

  4. IRBIT plays an important role in intracellular pH regulation, mediated by NHE3 (show SLC9A3 Antibodies), and further regulated by SPAK (show STK39 Antibodies).

  5. relationships between the WNK/SPAK (show STK39 Antibodies) and IRBIT/PP1 (show PPA1 Antibodies) sites in the regulation of Na+-HCO3- cotransporters

  6. conclude that AHCYL1 expression is associated with ovarian carcinogenesis as an oncogene (show RAB1A Antibodies) in chickens, whereas it plays the role of tumor suppressor in human EOC, suggesting a paradoxical function of AHCYL1 in ovarian carcinogenesis

  7. A NBCe1 (show SLC4A4 Antibodies)-B construct that lacks amino acid residues 2-16 of the amino-terminus is fully autoinhibited, but cannot be stimulated by IRBIT, indicating that autoinhibitory and IRBIT-binding determinants within the cytosolic amino-terminus are not identical.

  8. Both IRBIT (inositol 1,4,5-trisphosphate receptor-binding protein) and WNK [with no lysine (K)] kinase have been implicated as additional HCO(3)(-) secretory controllers.

  9. IRBIT opposes the effects of WNKs and SPAK (show STK39 Antibodies) by recruiting PP1 (show PPA1 Antibodies) to the complex to dephosphorylate CFTR (show CFTR Antibodies) and NBCe1 (show SLC4A4 Antibodies)-B, restoring their cell surface expression, in addition to stimulating their activities

  10. IRBIT is critically involved in mediating activation of NHE3 (show SLC9A3 Antibodies) by ANG II (show AGT Antibodies) via a Ca(2 (show CA2 Antibodies)+)/calmodulin (show CALM1 Antibodies)-dependent protein kinases II-dependent pathway.

Zebrafish Adenosylhomocysteinase-Like 1 (AHCYL1) interaction partners

  1. AHCYL1 has a different function from AHCY (show AHCY Antibodies) and plays an important role in embryogenesis by modulating inositol 1,4,5-trisphosphate receptor function for the intracellular calcium release

Mouse (Murine) Adenosylhomocysteinase-Like 1 (AHCYL1) interaction partners

  1. IRBIT forms signaling complexes with PIPKIalpha and NBCe1 (show SLC4A4 Antibodies)-B, whose activity is regulated by PI(4,5)P2.

  2. IRBIT suppresses CaMKIIalpha (show CAMK2 Antibodies) activity and contributes to catecholamine homeostasis through TH phosphorylation.

  3. Irbit was sequestered by InsP3 receptors (IP3Rs) in the endoplasmic reticulum

  4. IRBIT opposes the effects of WNKs and SPAK (show STK39 Antibodies) by recruiting PP1 (show PPP1CC Antibodies) to the complex to dephosphorylate CFTR (show CFTR Antibodies) and NBCe1 (show SLC4A4 Antibodies)-B, restoring their cell surface expression, in addition to stimulating their activities

  5. IRBIT can directly interact with the IP3R (show ITPR1 Antibodies), and that both the suppressor domain and the IP3-binding core of the IP3R (show ITPR1 Antibodies) are essential for a strong interaction.

  6. phosphorylation of Ser71 and Ser74 were sufficient to enable inhibition of IP3 binding to the IP3R (show ITPR1 Antibodies) by IRBIT

  7. Data show that pNBC1 activation requires the IRBIT PEST domain, while CFTR (show CFTR Antibodies) activation requires multiple domains, and suggest that IRBIT is a key coordinator of epithelial fluid and HCO3- secretion.

  8. Results sugest that IRBIT modulates the polyadenylation state of specific mRNAs, both by controlling the cytoplasmic/nuclear partitioning of Fip1 (show RRAGA Antibodies) and by inhibiting PAP (show ASAP1 Antibodies) activity, in response to a stimulus that alters its phosphorylation state.

AHCYL1 Antigen Profile

Protein Summary

The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with AHCYL1

  • adenosylhomocysteinase-like 1 (AHCYL1) antibody
  • adenosylhomocysteinase-like 1 (ahcyl1) antibody
  • adenosylhomocysteinase-like 1 (Ahcyl1) antibody
  • S-adenosylhomocysteine hydrolase-like 1 (ahcyl1) antibody
  • S-adenosylhomocysteine hydrolase-like 1 (Ahcyl1) antibody
  • 1110034F20Rik antibody
  • AA409031 antibody
  • AA414901 antibody
  • Ahcy-rs3 antibody
  • cb586 antibody
  • DCAL antibody
  • Irbit antibody
  • PRO0233 antibody
  • wu:fj66f02 antibody
  • XPVKONA antibody

Protein level used designations for AHCYL1

adenosylhomocysteinase-like 1 , putative adenosylhomocysteinase 2-like , S-adenosylhomocysteine hydrolase-like 1 , putative adenosylhomocysteinase 2 , DC-expressed AHCY-like molecule , S-adenosyl homocysteine hydrolase homolog , S-adenosyl-L-homocysteine hydrolase 2 , S-adenosylhomocysteine hydrolase-like protein 1 , adoHcyase 2 , dendritic cell expressed AHCY-like protein , inositol 1,4,5-trisphosphate receptor-binding protein , IP3R binding protein released with inositol 1,4,5-trisphosphate , IP3R-binding protein released with inositol 1,4,5-trisphosphate , S-adenosylhomocysteine hydrolase, related sequence 3

GENE ID SPECIES
100033080 Monodelphis domestica
100073556 Ornithorhynchus anatinus
100158541 Xenopus (Silurana) tropicalis
100407815 Callithrix jacchus
100451773 Pongo abelii
100590420 Nomascus leucogenys
447640 Xenopus laevis
419803 Gallus gallus
10768 Homo sapiens
611790 Canis lupus familiaris
505511 Bos taurus
362013 Rattus norvegicus
798918 Danio rerio
229709 Mus musculus
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