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This is a calmodulin-sensitive adenylyl cyclase.
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Following ethanol administration, phosphorylation of TrkB (show NTRK2 Antibodies) is significantly increased in the striatum of Adcyl1 and Adcyl6 knock-out mice.
Findings provide evidence to link activation of alpha7 nAChRs to a cAMP rise via AC1 (show HRASLS Antibodies), which defines a new signaling pathway employed by alpha7 nAChRs
Results indicate that thalamic AC1 (show HRASLS Antibodies) plays a major role in patterning and refinement of the mouse thalamocortical circuitry
Adenylyl cyclase-mediated effects contribute to increased isoprenaline-induced cardiac contractility in TRPM4 (show TRPM4 Antibodies)-deficient mice.
Results demonstrate that ADCY1 has an evolutionarily conserved role in hearing.
Data indicate that genetic ablation of RGS6 (show RGS6 Antibodies) expression resulted in anxiolytic and antidepressant behavior by enhancing signaling through the 5-HT1A receptor (show CC2D1A Antibodies)-adenylyl cyclase (AC) axis.
Contrast sensitivity is similarly reduced in Adcy1-/- mice.
These results suggest that AC1 (show HRASLS Antibodies) in retinal ganglion cell axons mediates the development of retinotopy and eye-specific segregation in the superior colliculus and dorsal lateral geniculate nucleus.
Data demonstrate that stimulating the dopamine Dreceptor is essential in maintaining the normal rhythmic production of adenylyl cyclase 1 from transcript to enzyme activity.
we have identified Adcy1 as a novel podocyte signaling protein that seems to have a role in compensatory physiological processes in the glomerulus.
This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning (By similarity).
ATP pyrophosphate-lyase 1
, Ca(2+)/calmodulin-activated adenylyl cyclase
, adenylate cyclase type 1
, adenylate cyclase type I
, adenylyl cyclase 1