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Adenylate Cyclase 10 (Soluble) Proteins (ADCY10)

The protein encoded by ADCY10 belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. Additionally we are shipping Adenylate Cyclase 10 (Soluble) Antibodies (30) and Adenylate Cyclase 10 (Soluble) Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADCY10 271639 Q8C0T9
ADCY10 55811 Q96PN6
Rat ADCY10 ADCY10 59320 Q9Z286
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Top Adenylate Cyclase 10 (Soluble) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ADCY10 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Adenylate Cyclase 10 (Soluble) (ADCY10) Interaction Partners

Mouse (Murine) Adenylate Cyclase 10 (Soluble) (ADCY10) interaction partners

  1. T1R3 (show TAS1R3 Proteins) and alpha-gustducin (show GNAT3 Proteins) exhibited a stage-dependent expression pattern during mouse development, and a cell-specific pattern during the spermatogenic cycle.

  2. Low concentration of endogenous GC is necessary and sufficient for induction of T1R3 (show TAS1R3 Proteins) expression. Higher concentrations may inhibit such induction. This inhibitory effect may be due, at least in part, to a direct action of GC on taste cells.

  3. T1R1/T1R3 have roles in regulating ERK1/2 and mTORC1 in MIN6 cells

  4. Mice possess two taste transduction pathways for sugars. One mediates behavioral attraction to sugars and requires an intact T1r2 (show TAS1R2 Proteins)+T1r3 (show TAS1R3 Proteins). The other mediates cephalic phase insulin (show INS Proteins) release but does not require an intact T1r2 (show TAS1R2 Proteins)+T1r3 (show TAS1R3 Proteins).

  5. Taken together, our study raises the possibility that MyoD (show MYOD1 Proteins) and Myogenin (show MYOG Proteins) might control skeletal muscle metabolism and homeostasis through the regulation of T1R3 (show TAS1R3 Proteins) promoter activity.

  6. Mice lacking the Tas1r3 (show TAS1R3 Proteins) taste receptor gene display impaired glucose metabolism.

  7. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 (show GRM4 Proteins) knockout mice

  8. T1R3 (show TAS1R3 Proteins) is expressed mainly in beta-cells and the expression levels are different depending upon the nutritional and metabolic conditions.

  9. In the Tas1r3 (show TAS1R3 Proteins)-/- strain, in addition to disappearance of taste preference for sucrose, glucose tolerance is also substantially reduced, and insulin (show INS Proteins) resistance is observed.

  10. human and mouse membrane trafficking systems for sweet taste receptors T1r2 (show TAS1R2 Proteins) and T1r3 (show TAS1R3 Proteins)

Human Adenylate Cyclase 10 (Soluble) (ADCY10) interaction partners

  1. The data support an important role for prostaglandin activation of sAC and PKA in H2O2-induced barrier disruption.

  2. Evaluation of soluble adenylyl cyclase expression using R21 (show OPRK1 Proteins) antibody is a useful diagnostic adjunct in the evaluation of margins of LM during slow Mohs surgery.

  3. shows that in fibroblast cultures inhibition by KH7 of production in the mitochondrial matrix by soluble adenylyl cyclase

  4. Crystal structures of human ADCY10 catalytic domains in complex with nucleotides.

  5. Soluble adenylyl cyclase plays a role in the regulation of basal cCMP and cUMP.

  6. sAC is a regulator of gene expression involved in aldosterone signaling and an important regulator of endothelial stiffness.

  7. sAC is necessary for normal glucose-stimulated insulin (show INS Proteins) secretion in vitro and in vivo.

  8. Significant overexpression of soluble type 10 adenylyl cyclase (sAC), an alternative source of cAMP, was found in human prostate carcinoma.

  9. Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body.

  10. sAC may play a role in the pathogenesis of certain hyperproliferative skin disorders via modulation of gene expression

Pig (Porcine) Adenylate Cyclase 10 (Soluble) (ADCY10) interaction partners

  1. functional ADCY10 ortholog proteins exist in the heads of boar spermatozoa.

Adenylate Cyclase 10 (Soluble) (ADCY10) Protein Profile

Protein Summary

The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Genetic variations in this gene are associated with absorptive hypercalciuria type 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ADCY10

  • adenylate cyclase 10 (soluble) (ADCY10)
  • adenylate cyclase 10 (Adcy10)
  • adenylate cyclase 10 (soluble) (Adcy10)
  • soluble adenylyl cyclase (SAC)
  • taste receptor, type 1, member 3 (Tas1r3)
  • 4930431D04Rik protein
  • 4931412F17 protein
  • ADCY10 protein
  • HCA2 protein
  • RP1-313L4.2 protein
  • Sac protein
  • SACI protein
  • SACY protein
  • T1r3 protein

Protein level used designations for ADCY10

adenylate cyclase 10 (soluble) , soluble adenylyl cyclase , adenylate cyclase type 10 , germ cell soluble adenylyl cyclase , testicular soluble adenylyl cyclase , 3',5'-cyclic AMP synthetase , AH-related protein , ATP pyrophosphate-lyase , hsAC , testicular soluble adenylyl cyclase (SAC) , adenylate cyclase type 10 variant I (full-length form) , adenylate cyclase type 10 variant II (truncated form) , saccharin preference protein , sweet taste receptor T1R3 , taste receptor type 1 member 3

GENE ID SPECIES
431650 Gallus gallus
469570 Pan troglodytes
481790 Canis lupus familiaris
698566 Macaca mulatta
100601811 Nomascus leucogenys
271639 Mus musculus
55811 Homo sapiens
521844 Bos taurus
59320 Rattus norvegicus
480087 Canis lupus familiaris
100157188 Sus scrofa
100008902 Oryctolagus cuniculus
83771 Mus musculus
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