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anti-Adenylate Kinase 2 (AK2) Antibodies

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Additionally we are shipping Adenylate Kinase 2 Proteins (29) and Adenylate Kinase 2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AK2 204 P54819
AK2 11637 Q9WTP6
AK2 24184 P29410
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Top anti-Adenylate Kinase 2 Antibodies at antibodies-online.com

Showing 10 out of 109 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-AK2 Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-AK2 Pab (ABIN392742) is used in Western blot to detect AK2 in Jurkat cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-AK2 Pab (ABIN392741) is used in Western blot to detect AK2 in mouse kidney tissue lysate. Western blot analysis of anti-AK2 Antibody (N-term) (ABIN392741) in CEM cell line lysates (35 µg/lane). AK2(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-AK2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: RPMI 8226 cell lysate WB Suggested Anti-AK2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: RPMI 8226 cell lysate  AK2 is strongly supported by BioGPS gene expression data to be expressed in RPMI-8226 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IP, IHC (p), ELISA, WB Immunochemical staining of human AK2 in human kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human AK2 in human liver with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 16 Days
$218.90
Details

AK2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Adenylate Kinase 2 Antibodies

  1. Human Polyclonal Adenylate Kinase 2 Primary Antibody for IHC (p), WB - ABIN392742 : Noma, Song, Yoon, Tanaka, Nakazawa: cDNA cloning and tissue-specific expression of the gene encoding human adenylate kinase isozyme 2. in Biochimica et biophysica acta 1998 (PubMed)
    Show all 3 references for ABIN392742

  2. Human Polyclonal Adenylate Kinase 2 Primary Antibody for EIA, IHC (p) - ABIN360624 : Lee, Kim, Lee, Kim, Lee, Park, Choe: Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues. in Journal of biochemistry 1998 (PubMed)
    Show all 3 references for ABIN360624

  3. Human Polyclonal Adenylate Kinase 2 Primary Antibody for IHC (p), WB - ABIN392741 : Valenti, Tullo, Caratozzolo, Merafina, Scartezzini, Marra, Vacca: Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy. in The Biochemical journal 2010 (PubMed)
    Show all 3 references for ABIN392741

  4. Human Polyclonal Adenylate Kinase 2 Primary Antibody for EIA, IHC (p) - ABIN360625 : Lee, Kim, Lee, Kang, Choe, Lee, Lim, Kim, Park, Choe: Cloning and characterization of cDNA for human adenylate kinase 2A. in Biochemistry and molecular biology international 1997 (PubMed)
    Show all 3 references for ABIN360625

  5. Dog (Canine) Polyclonal Adenylate Kinase 2 Primary Antibody for WB - ABIN2782460 : Köhler, Gahm, Noma, Nakazawa, Orrenius, Zhivotovsky: Release of adenylate kinase 2 from the mitochondrial intermembrane space during apoptosis. in FEBS letters 1999 (PubMed)

More Antibodies against Adenylate Kinase 2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Adenylate Kinase 2 (AK2) interaction partners

  1. Adenylate kinase 2 deficiency limits survival and regulates various genes during larval stages of Drosophila melanogaster.

  2. Data demonstrate that adenylate kinase 2 plays a critical role in adenine nucleotide metabolism in the mitochondrial intermembrane space and is essential for growth.

Zebrafish Adenylate Kinase 2 (AK2) interaction partners

  1. Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.

  2. Knockdown of zebrafish ak2 also leads to aberrant leukocyte development, stressing the evolutionarily conserved role of AK2.

Human Adenylate Kinase 2 (AK2) interaction partners

  1. AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages.

  2. results suggest that AK2 is an associated activator of DUSP26 (show DUSP26 Antibodies) and suppresses cell proliferation by FADD (show FADD Antibodies) dephosphorylation, postulating AK2 as a negative regulator of tumour growth.

  3. AK2 is indispensable for neutrophil differentiation, indicating a possible causative link between AK2 deficiency and neutropenia in reticular dysgenesis.

  4. These results suggest that, acting in concert with FADD (show FADD Antibodies) and caspase-10 (show CASP10 Antibodies), AK2 mediates a novel intrinsic apoptotic pathway that may be involved in tumorigenesis.

  5. The alpha-borano or alpha-H on PMEA and PMPA were detrimental to the activity of recombinant human AMP (show APRT Antibodies) kinases 2

  6. Biallelic mutations in AK2 (adenylate kinase 2) in seven individuals affected with reticular dysgenesis and sensorineural deafness, were identified.

  7. The gene encoding the mitochondrial energy metabolism enzyme adenylate kinase 2 (AK2) is mutated in individuals with reticular dysgenesis.

Mouse (Murine) Adenylate Kinase 2 (AK2) interaction partners

  1. results suggest that AK2 is an associated activator of DUSP26 (show DUSP26 Antibodies) and suppresses cell proliferation by FADD (show FADD Antibodies) dephosphorylation, postulating AK2 as a negative regulator of tumour growth.

  2. In addition to AK1 (show AK1 Antibodies) and AK2, which we previously demonstrated are present in outer dense fibers (show ODF1 Antibodies) and mitochondrial sheath of the mouse sperm tail, we show that another AK, AK8 (show AK8 Antibodies), is present in a third flagellar compartment, the axoneme.

  3. Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response.

  4. Reduced Akt2 (show AKT2 Antibodies) leads to up-regulation of Rab4a (show RAB4A Antibodies) expression in cardiomyocytes in a cell-autonomous fashion that may involve activation of PPARalpha (show PPARA Antibodies).

  5. AK2 in the flagellar accessory structures provides a mechanism to buffer the adenylate energy charge for sperm motility. Ak2 protein was localized to the mitochondrial sheath in the sperm midpiece.

  6. Biallelic mutations in AK2 (adenylate kinase 2) in seven individuals affected with reticular dysgenesis and sensorineural deafness, were identified.

Adenylate Kinase 2 (AK2) Antigen Profile

Protein Summary

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates\; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.

Gene names and symbols associated with AK2

  • Adenylate kinase-2 (Adk2) antibody
  • adenylate kinase 2 (AK2) antibody
  • adenylate kinase 2 (ak2) antibody
  • adenylate kinase 2 (Ak2) antibody
  • adenylate kinase 2 (AT5G50370) antibody
  • ADK-2 antibody
  • ADK2 antibody
  • Ak-2 antibody
  • AK 2 antibody
  • anon-Dak2 antibody
  • BcDNA:SD09634 antibody
  • CG3140 antibody
  • D4Ertd220e antibody
  • Dak2 antibody
  • Dmel\\CG3140 antibody
  • MXI22.8 antibody
  • MXI22_8 antibody
  • NV10896 antibody
  • wu:fb34f05 antibody
  • wu:fj80e03 antibody

Protein level used designations for AK2

Adk2-PA , CG3140-PA , adenylate kinase-2 , adenylate kinase 2 , AK 2 , ATP-AMP transphosphorylase 2 , ATP:AMP phosphotransferase , adenylate kinase 2, mitochondrial , adenylate monophosphate kinase , adenylate kinase isoenzyme 2, mitochondrial , adenylate kinase isozyme 2

GENE ID SPECIES
37834 Drosophila melanogaster
428227 Gallus gallus
448011 Xenopus (Silurana) tropicalis
456723 Pan troglodytes
709737 Macaca mulatta
100123971 Nasonia vitripennis
100171703 Pongo abelii
321793 Danio rerio
379924 Xenopus laevis
204 Homo sapiens
478145 Canis lupus familiaris
11637 Mus musculus
24184 Rattus norvegicus
280716 Bos taurus
835104 Arabidopsis thaliana
Selected quality suppliers for anti-Adenylate Kinase 2 (AK2) Antibodies
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