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anti-Adenylosuccinate Lyase (ADSL) Antibodies

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. Additionally we are shipping Adenylosuccinate Lyase Proteins (10) and Adenylosuccinate Lyase Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADSL 158 P30566
ADSL 11564 P54822
ADSL 315150  
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Top anti-Adenylosuccinate Lyase Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Adenylosuccinate Lyase Antibody [NBP1-87406] - Lane 1: Marker [kDa] 207, 110, 79, 49, 32, 25, 17.1 | Lane 2: RT-4 | Lane 3: EFO-21 | Lane 4: A-431 | Lane 5: Liver | Lane 6: Tonsil Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody [NBP1-87406] - Staining of human tonsil shows strong cytoplasmic positivity in reaction center cells. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ADSL Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Muscle Sample Type: 1. Hamster CHO K1 cells (20ug)2. HeLa skin cells(100ug)3. HEK273 cells (100ug)4. HepG2 cells (100ug)5. purified human ADSL protein (40ng)Primary Dilution: 1:2000Secondary Antibody: Clean-Blot IP detection Reagent and KitSecondary Dilution: 1:2000Image Submitted By: V. Skopova, M. ZikanovaInstitute of Inherited Metabolic Disorders, Charles University in Prague and General Hopspital in Prague 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Adenylosuccinate Lyase Antibody [NBP1-87462] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody [NBP1-87462] - Staining of human liver shows moderate nuclear and cytoplasmic positivity in hepatocytes 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated FACS, IHC, WB Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ADSL mouse monoclonal antibody. (ABIN2452704) Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-ADSL mouse monoclonal antibody. (ABIN2452704) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Adenylosuccinate Lyase Antibody [NBP2-15296] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution. Western Blot: Adenylosuccinate Lyase Antibody [NBP2-15296] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE ASL antibody, antibody diluted at 1:1000. 0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Dog Mouse Un-conjugated FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-Adenylosuccinate Lyase mouse monoclonal antibody. Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody (2D10) [NBP2-03107] - Staining of paraffin-embedded Human Kidney tissue using anti-Adenylosuccinate Lyase mouse monoclonal antibody. 0.1 mL Log in to see 6 to 9 Days
$513.19
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of ADSL staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Western blot analysis of ADSL expression in HepG2 (A), Jurkat (B), mouse heart (C), rat brain (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$323.13
Details

ADSL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Adenylosuccinate Lyase Antibodies

  1. Human Polyclonal Adenylosuccinate Lyase Primary Antibody for WB - ABIN611329 : Blumstein, Faundez, Nakatsu, Saito, Ohno, Kelly: The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2001 (PubMed)
    Show all 3 references for ABIN611329

  2. Human Polyclonal Adenylosuccinate Lyase Primary Antibody for ICC, IF - ABIN4278427 : Baresova, Skopova, Sikora, Patterson, Sovova, Zikanova, Kmoch: Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency. in Human molecular genetics 2012 (PubMed)
    Show all 2 references for ABIN4278427

  3. Human Polyclonal Adenylosuccinate Lyase Primary Antibody for IHC, IHC (p) - ABIN4278428 : van Straten, van Steenbeek, Grinwis, Favier, Kummeling, van Gils, Fieten, Groot Koerkamp, Holstege, Rothuizen, Spee: Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. in PLoS ONE 2014 (PubMed)

More Antibodies against Adenylosuccinate Lyase Interaction Partners

Human Adenylosuccinate Lyase (ADSL) interaction partners

  1. Case Report: Malaysian patient compound heterozygous for two novel ADSL mutations giving rise to adenylosuccinate lyase deficiency.

  2. Missense mutations in the adenylosuccinate lyase is associated with Adenylosuccinate lyase deficiency, an inborn error of purine metabolism characterized by neurological and physiological symptoms.

  3. structural and biochemical characterization data of WT and mutant R303C ADSL by enzyme kinetics, product binding by isothermal titration calorimetry and X-ray crystallography to reveal the effects of the R303C mutation that results in a nonparallel reduction in enzyme activity

  4. Results proved in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency that various mutations of ADSL destabilize to various degrees purinosome assembly and found that the ability to form purinosomes correlates with clinical phenotypes of individual ADSL patients.

  5. D-ribose administration in Polish patients with adenylosuccinate lyase deficiency was accompanied by neither reduction in seizure frequency nor growth enhancement.

  6. the cases of the only three children diagnosed to date in the United Kingdom with adenylosuccinate lyase deficiency

  7. Mutation of a nuclear respiratory factor 2 (show GABPb Antibodies) binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency.

  8. Mutations at position 276 result in structurally impaired adenylosuccinate lyases which are assembled into the defective tetramers associated with the mild variant of ADSL deficiency in humans.

  9. Variable expression of ADSL deficiency is reported in three patients belonging to a family which originates from Portugal.

  10. a mutation in adenylosuccinate lyase may be associated with autism

Pig (Porcine) Adenylosuccinate Lyase (ADSL) interaction partners

  1. Expression levels of ADSL, GARS-AIRS-GART (show GART Antibodies), and DGAT1 (show DGAT1 Antibodies) were higher in longissimus lumborum muscle than in heart or liver tissues

Adenylosuccinate Lyase (ADSL) Antigen Profile

Protein Summary

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ADSL

  • adenylosuccinate lyase-like (LOC100070427) antibody
  • adenylosuccinate lyase (adsl) antibody
  • adenylosuccinate lyase (ADSL) antibody
  • adenylosuccinate lyase (ASL) antibody
  • adenylosuccinate lyase (purB) antibody
  • adenylosuccinase; ASL (purB) antibody
  • adenylosuccinate lyase (purB,adsL) antibody
  • adenylosuccinate lyase (Mrub_2293) antibody
  • Adenylosuccinate lyase (Mmah_0591) antibody
  • adenylosuccinate lyase (Arnit_0089) antibody
  • adenylosuccinate lyase (Mesil_1058) antibody
  • adenylosuccinate lyase (Slip_0597) antibody
  • adenylosuccinate lyase (Trad_2452) antibody
  • adenylosuccinate lyase (Deba_0652) antibody
  • adenylosuccinate lyase (Toce_1174) antibody
  • Adenylosuccinate lyase (Acear_2324) antibody
  • Adenylosuccinate lyase (Igag_0272) antibody
  • adenylosuccinate lyase (Saut_2156) antibody
  • Adenylosuccinate lyase (Fbal_1996) antibody
  • adenylosuccinate lyase (Ndas_2434) antibody
  • adenylosuccinate lyase (Ilyop_0196) antibody
  • adenylosuccinate lyase (Lbys_2961) antibody
  • adenylosuccinate lyase (Mfer_0576) antibody
  • adenylosuccinate lyase (Palpr_2192) antibody
  • adenylosuccinate lyase (Calni_0061) antibody
  • adenylosuccinate lyase (Ftrac_3746) antibody
  • L-aspartase-like family protein (AT1G36280) antibody
  • Adenylosuccinate lyase (Olsu_1764) antibody
  • adenylosuccinate lyase (Adsl) antibody
  • Adl antibody
  • adsL antibody
  • AMPS antibody
  • ASASE antibody
  • Asl antibody
  • F15C21.8 antibody
  • F15C21_8 antibody
  • fi60b04 antibody
  • MGC53383 antibody
  • MGC69239 antibody
  • purB antibody
  • wu:fi60b04 antibody
  • zgc:56061 antibody

Protein level used designations for ADSL

adenylosuccinate lyase , Adenylosuccinate lyase , adenylosuccinate lyase-like , adenylosuccinase , ASase , adenylosuccinate lyase 1 , test , ASL , adenysuccinate lyase

GENE ID SPECIES
100070427 Equus caballus
334431 Danio rerio
380285 Xenopus laevis
448055 Xenopus (Silurana) tropicalis
709259 Macaca mulatta
812659 Plasmodium falciparum 3D7
2648977 Corynebacterium diphtheriae NCTC 13129
3430067 Haemophilus influenzae 86-028NP
4946884 Saccharopolyspora erythraea NRRL 2338
8880402 Meiothermus ruber DSM 1279
8982739 Methanohalophilus mahii DSM 5219
9170222 Arcobacter nitrofigilis DSM 7299
9250551 Meiothermus silvanus DSM 9946
9273377 Syntrophothermus lipocalidus DSM 12680
9281455 Truepera radiovictrix DSM 17093
9493100 Desulfarculus baarsii DSM 2075
9510817 Thermosediminibacter oceani DSM 16646
9514386 Acetohalobium arabaticum DSM 5501
9715588 Ignisphaera aggregans DSM 17230
9759721 Sulfurimonas autotrophica DSM 16294
9770777 Ferrimonas balearica DSM 9799
100393664 Callithrix jacchus
9246284 Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111
9867696 Ilyobacter polytropus DSM 2926
9956841 Leadbetterella byssophila DSM 17132
9962300 Methanothermus fervidus DSM 2088
9999856 Paludibacter propionicigenes WB4
10008059 Calditerrivibrio nitroreducens DSM 19672
10013912 Marivirga tractuosa DSM 4126
840534 Arabidopsis thaliana
9500628 Olsenella uli DSM 7084
158 Homo sapiens
11564 Mus musculus
315150 Rattus norvegicus
474499 Canis lupus familiaris
510949 Bos taurus
396540 Gallus gallus
100170844 Sus scrofa
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