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Adherens Junctions Associated Protein 1 Proteins (AJAP1)

Plays a role in cell adhesion and cell migration (By similarity).. Additionally we are shipping AJAP1 Antibodies (17) and AJAP1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AJAP1 230959 A2ALI5
AJAP1 687031 Q4W8E7
AJAP1 55966 Q9UKB5
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Top AJAP1 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,678.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,744.50
Details

AJAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Rat (Rattus)

Human ,
,

More Proteins for Adherens Junctions Associated Protein 1 (AJAP1) Interaction Partners

Human Adherens Junctions Associated Protein 1 (AJAP1) interaction partners

  1. Reduced Expression of Adherens Junctions Associated Protein 1 is associated with Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy.

  2. These findings indicate that downregulated AJAP1 transcription may serve as a novel tumor biomarker to predict recurrence of ESCC after esophagectomy.

  3. Article summarizes and discusses current knowledge that may identify AJAP1 as a tumor suppressor in gliomas. [Review]

  4. Results show that AJAP1 is dysregulated at an early stage of gliomagenesis and may suppress glioma cell invasion and proliferation, which suggests that AJAP1 may be a potential diagnostic and prognostic marker for gliomas

  5. AJAP1 suppressed the expression of MAGEA2 and inhibited the transcriptional activity of MAGEA2 in glioma cells.

  6. We also identified a significant genetic association between caries of the mid- dentition tooth surfaces and AJAP1 (p value = 2e-8), a gene possibly involved in tooth development.

  7. This work shows the significant loss of expression of AJAP1 in glioblastoma and provides evidence of its role in the highly migratory characteristic of these tumors.

  8. Both genetic (gene deletion) and epigenetic alterations (promoter methylation) are likely mechanisms that inactivate the putative tumor suppressor AJAP1 in gliomas, which contributes to poor prognosis.

  9. Data show that overexpression of shrew-1 leads to preformation of an E-cadherin (show CDH1 Proteins)/EGF receptor (show EGFR Proteins)/HER2 (show ERBB2 Proteins)/src-kinase (show CSK Proteins)/shrew-1 signaling complex and accelerated E-cadherin (show CDH1 Proteins) internalization.

  10. While a mutation was not detected in the coding region of the SHREW1 gene in oligodendrogliomas, SHREW1 expression restoration resulted in suppression of cell adhesion and migration, thus, SHREW1 inactivation may lead to oligodendroglial tumorigenesis.

AJAP1 Protein Profile

Protein Summary

Plays a role in cell adhesion and cell migration (By similarity).

Gene names and symbols associated with AJAP1

  • adherens junction associated protein 1 (Ajap1)
  • adherens junctions associated protein 1 (AJAP1)
  • Gm573 protein
  • MOT8 protein
  • neumo48 protein
  • RP3-426F10.1 protein
  • SHREW-1 protein
  • SHREW1 protein

Protein level used designations for AJAP1

adherens junction-associated protein 1 , likely ortholog of H. sapiens transmembrane protein SHREW1 , Neumo48 , adherens junction associated protein 1 , membrane protein shrew-1 , transmembrane protein SHREW1

GENE ID SPECIES
230959 Mus musculus
687031 Rattus norvegicus
55966 Homo sapiens
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