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Required for depolarization-dependent survival of cultured cerebellar granule neurons. Additionally we are shipping AMIGO2 Antibodies (67) and AMIGO2 Kits (5) and many more products for this protein.
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Report AMIGO2 mRNA expression in CA2 (show CA2 Proteins)/Ca3a hippocampal region of mouse brain.
Expression of ali1 promotes depolarization-dependent survival of cerebellar granule neurons. Mouse ali1 mapped to a chromosome 15 locus syntenic to candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.
AMIGO2 is an important regulator of the PDK1 (show PDK1 Proteins)-Akt (show AKT1 Proteins) pathway.
Stable expression of a DEGA/AMIGO-2 antisense construct led to altered morphology, increased ploidy, chromosomal instability, decreased cell adhesion/migration, and a nearly complete abrogation of tumorigenicity in nude mice.
Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain (By similarity).
adhesion molecule with Ig-like domain 2
, amphoterin induced gene 2
, Amphoterin-induced protein 2
, amphoterin-induced protein 2-like
, alivin 1
, amphoterin induced gene and ORF 2
, amphoterin-induced protein 2
, transmembrane protein AMIGO2
, differentially expressed in gastric adenocarcinoma
, differentially expressed in gastric adenocarcinomas