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Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins..
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Human Polyclonal ADRA2A Primary Antibody for IF, IHC - ABIN1533597
Kobilka, Matsui, Kobilka, Yang-Feng, Francke, Caron, Lefkowitz, Regan: Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. in Science (New York, N.Y.) 1987
This study showed that reduced expression of the alpha2A-adrenoceptor (Adra2a) which modulate antidepressant action in hippocampus.
Fzd5 and Trvp6 are expressed in the epithelial layer of the prospective pyroric and glandular stomach, respectively and Adra2a is expressed in the mesenchymal region of the stomach primordium at the beginning of morphogenesis.
The sympathetic hyperactivity present in alpha2A/alpha2C-ARKO (show CYP19A1 Antibodies) mice alters vascular reactivity only in certain types of arteries
Data indicate that activation of alpha(2A) adrenergic receptor (alpha(2A)AR) signaling disrupts transgenic amyloid precursor protein (APP (show APP Antibodies)) interaction with sorting-related receptor with A repeat (SorLA (show SORL1 Antibodies)) in cells and brain.
Thus, our study reveals distinct actions of PBN afferents within the BNST and suggests that alpha(2A)-AR agonists may filter excitatory transmission in the BNST by inhibiting a component of the PBN input while enhancing the actions of other inputs.
The time course of Adra2a- and dopamine D2R (show DRD2 Antibodies)-mediated transmission reflects underlying differences in the extent of spillover and pooling of inhibitory postsynaptic potentials (IPSPs).
Activation of alpha2A-AR and muscarinic M3 receptors affects the initial [Ca(2 (show CA2 Antibodies)+)] response to increase of glucose from 3 to 20mM in BETA-cells.
Canonical betaAR-mediated signaling coupled to PKA activation results in phosphorylation of spinophilin (show PPP1R9B Antibodies), disrupting its interaction with alpha2AARs and accelerating alpha2AAR endocytic responses.
conformational change of alpha(2A)AR by voltage is independent from receptor-G protein docking and regulates receptor signaling, including beta-arrestin binding, activation of G proteins, and G protein-activated inwardly rectifying K(+) currents
adra2 receptor stimulation significantly modifies migration of cortical interneurons.
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins.
alpha-2A adrenergic receptor
, alpha-2A adrenoceptor
, alpha-2A adrenoreceptor
, alpha2A-adrenergic receptor
, subtype alpha2-C10
, adrenergic receptor, alpha 2a
, adrenergic, alpha-2A-, receptor
, alpha-2D adrenergic receptor