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This intronless gene belongs to the G-protein-coupled receptor superfamily, which includes transmembrane proteins that play a role in signal transduction across biological membranes resulting in a variety of physiological responses. Additionally we are shipping ADRB2 Antibodies (12) and many more products for this protein.
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Data show that inhibitory (Galphai2 (show GNAI2 ELISA Kits)) and stimulatory (GalphasL) G-protein subunits produced minor atrophic and hypertrophic changes in muscle mass, and Galphai2 (show GNAI2 ELISA Kits) over-expression prevented AAV:beta2-adrenoceptor (beta2-AR) mediated hypertrophy.
Immune cell-expressed beta2AR plays an essential role in regulating the early inflammatory repair response to acute myocardial injury by facilitating cardiac leukocyte infiltration.
In epileptic seizures mouse model, Pkdl deficiency leads to the loss of beta2AR on neuronal cilia, reduction in cAMP levels in the central nervous system, and reduction in the activation of cAMP response element-binding protein (show CREB ELISA Kits).
Beta2AR overexpression enhances endothelial progenitor cells (EPC (show TCF21 ELISA Kits)) functions in vitro and enhances the vascular repair abilities of EPCs in vivo via the beta2AR/Akt (show AKT1 ELISA Kits)/eNOS (show NOS3 ELISA Kits) pathway.
Housing temperature-induced stress drives therapeutic resistance in murine tumor models through beta2-adrenergic receptor activation.
Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways.
our results demonstrate that the beta2-adrenergic receptor is a key regulator of hepatic autophagy, and that the beta-blocker propranolol can independently induce a late block in autophagy.
promotes the M2 macrophage phenotype in mouse models of endotoxemia and LPS (show TLR4 ELISA Kits)-induced acute lung injury
This study demonstrated that TNFalpha (show TNF ELISA Kits) plays a role in insulin (show INS ELISA Kits) resistance in beta2KO mice.
beta2AR-mediated signals inhibited lymph node egress of antigen-primed T cells and reduced their recruitment into peripheral tissues.
This intronless gene belongs to the G-protein-coupled receptor superfamily, which includes transmembrane proteins that play a role in signal transduction across biological membranes resulting in a variety of physiological responses. The encoded protein is a beta-2 adrenergic receptor which is activated by catecholamine ligands such as adrenaline and epinephrine. The protein participates in the classical signaling pathway involving G protein, adenylyl cyclase, cAMP (3'-5'-cyclic adenosine monophosphate) and protein kinase A (PKA). In humans, this gene is implicated in susceptibility to nocturnal asthma, obesity and type 2 diabetes.
, beta-2 adrenergic receptor
, beta-2 adrenoceptor
, beta-2 adrenoreceptor
, Adrenergic beta 2- receptor surface
, adrenergic receptor, beta 2
, adrenergic, beta-2-, receptor, surface