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Adrenocorticotropic hormone Proteins (ACTH)

ACTH encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. Additionally we are shipping Adrenocorticotropic hormone Antibodies (191) and Adrenocorticotropic hormone Kits (64) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACTH 18976 P01193
ACTH 5443 P01189
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Top Adrenocorticotropic hormone Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Synthetic Human Un-conjugated 2 mg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 5 applications Log in to see 1 to 2 Days
HOST_Synthetic Human Un-conjugated 100 μg Log in to see 11 to 13 Days

ACTH Proteins by Origin and Source

Origin Expressed in
Mouse (Murine) ,
Human ,
Rat (Rattus) ,

More Proteins for Adrenocorticotropic hormone (ACTH) Interaction Partners

Mouse (Murine) Adrenocorticotropic hormone (ACTH) interaction partners

  1. Data suggest that the solitary tract pro-opiomelanocortin (show POMC Proteins) (NTSPOMC) neurons were involved in cardiorespiratory control and endogenous analgesia.

  2. hypothalamic arcuate nucleus (Arc (show NOL3 Proteins))POMC (show POMC Proteins)-deficient mice, which develop severe obesity and insulin (show INS Proteins) resistance, unexpectedly exhibit improved glucose tolerance and remain protected from hyperglycemia via decreased renal GLUT2 (show SLC2A2 Proteins) expression and glycosuria.

  3. Hypomethylation of POMC (show POMC Proteins) promoter occurred in the hypothalamus of the high sucrose diet offspring compared with controls.

  4. Together, these results suggest that alpha-MSH alleviates Dex-induced damages to cultured osteoblasts through activating MC4R (show MC4R Proteins)-SphK1 (show SPHK1 Proteins) signaling.

  5. These data indicate that glucose induces distinct excitatory synaptic plasticity in different subpopulations of POMC (show POMC Proteins) neurons.

  6. Although genetic deletion of either Atg12 (show ATG12 Proteins) or Atg5 (show ATG5 Proteins) renders POMC (show POMC Proteins) neurons autophagy-deficient, mice lacking Atg5 (show ATG5 Proteins) in POMC (show POMC Proteins) neurons do not exhibit these phenotypes.

  7. Data indicate that LIM-homeodomain (show LHX2 Proteins) transcription factor Islet 1 (show ISL1 Proteins) is necessary for hypothalamic proopiomelanocortin (show POMC Proteins) gene (Pomc (show POMC Proteins)) expression during embryogenesis.

  8. these results reveal that cooperative interactions between the enhancers confer robustness of Pomc (show POMC Proteins) expression against gene regulatory disturbances and preclude deleterious metabolic phenotypes caused by Pomc (show POMC Proteins) deficiency in adulthood

  9. In contrast to mice with total hypothalamic Pomc (show POMC Proteins) deficiency, which are severely obese, mice with Lepr (show LEPR Proteins)-restricted Pomc (show POMC Proteins) expression displayed fully normal body weight, food consumption, glucose homeostasis, and locomotor activity.

  10. Data suggest FoxO1 (forkhead box O1 (show FOXO1 Proteins)) region Gly140-Leu160 (Gln145, Arg147 (show DHX40 Proteins), Lys148, Arg153, Arg154) is critical for FoxO1 (show FOXO1 Proteins) interaction with Stat3 (show STAT3 Proteins) (signal transducer/activator of transcription (show STAT1 Proteins) 3) in down-regulation of leptin (show LEP Proteins)-induced Pomc (show POMC Proteins) transcription.

Human Adrenocorticotropic hormone (ACTH) interaction partners

  1. these common variants in PCSK1 (show PCSK1 Proteins) and POMC (show POMC Proteins) were not the major cause of obesity in the Thai subjects sampled. However, variants in PCSK1 (show PCSK1 Proteins) did affect cholesterol level, LDL-C level, and waist circumference.

  2. ACTH (show POMC Proteins) was readily detected at significantly higher levels in regions of ACTH (show POMC Proteins)-secreting adenomas and in normal anterior adenohypophysis compared with non-secreting adenoma and neurohypophysis.

  3. CSF (show CSF2 Proteins) POMC (show POMC Proteins) was higher in lean vs. overweight/obese subjects.

  4. There was a non-linear association between leukocyte telomere length and plasma ACTH (show POMC Proteins) after laboratory stressor in elderly adults.

  5. Synovial fluid alpha-MSH levels showed an independent and negative correlation with articular cartilage degeneration in patients with knee ACL (show ACLY Proteins) deficiency.

  6. This study suggest the involvement of genetic variants of POMC (show POMC Proteins) in the outcome of antidepressant treatment in patients with MDD, and indicate the possibility of an interaction of this association with stressful life events.

  7. Term infants born with meconium-stained amniotic fluid (MSAF) and who experienced respiratory distress had significantly lower levels of ACTH (show POMC Proteins) and cortisol at birth compared with well term infants born with MSAF or clear amniotic fluid.

  8. POMC (show POMC Proteins)-positive expression is a novel, independent poor prognostic marker.

  9. the hypothalamic proopiomelanocortin (show POMC Proteins) neurons, have a key role in the control of food intake and energy metabolism.

  10. Report clinicopathological/immunohistochemical features of ACTH (show POMC Proteins)-secreting pancreatic neoplasms.

Cow (Bovine) Adrenocorticotropic hormone (ACTH) interaction partners

  1. The association has been reported between polymorphisms of the CRH (show CRH Proteins) and POMC (show POMC Proteins) genes with economic traits in Korean cattle.

  2. Expression of the hepatic endocannabinoid system and proopiomelanocortin (show POMC Proteins) was altered by plane of dietary energy prepartum particularly during the first 2-week postpartum.

  3. Significant associations were observed between POMC (show POMC Proteins) c.288C>T with start-of-finishing weight (SOF (show GJA1 Proteins) WT; P = 0.04), hot carcass weight (HCW; P = 0.02), average fat and grade fat (both P = 0.05), carcass rib-eye area (REA (show PHB2 Proteins); P = 0.03) and marbling

  4. The polymorphism of POMC (show POMC Proteins) gene is associated with the growth traits of Nanyang cattle.

Pig (Porcine) Adrenocorticotropic hormone (ACTH) interaction partners

  1. The expression of the genes coding for proopiomelanocortin (POMC (show POMC Proteins)), proenkephalin (PENK (show PENK Proteins)) and prodynorphin (PDYN (show PDYN Proteins)) in porcine luteal cells isolated from corpora lutea (CL) collected on days 3-6, 8-10 and 13-16 of the oestrous cycle is reported.

Adrenocorticotropic hormone (ACTH) Protein Profile

Protein Summary

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

Gene names and symbols associated with ACTH

  • pro-opiomelanocortin-alpha (Pomc)
  • proopiomelanocortin (POMC)
  • ACTH protein
  • alpha-MSH protein
  • alphaMSH protein
  • BE protein
  • Beta-LPH protein
  • beta-MSH protein
  • CLIP protein
  • Gamma-LPH protein
  • gamma-MSH protein
  • LPH protein
  • MSH protein
  • NPP protein
  • POC protein
  • Pomc-1 protein
  • Pomc1 protein

Protein level used designations for ACTH

adrenal corticotropic hormone , adrenocorticotropic hormone , alpha-melanocyte stimulating hormone , beta-endorphin , corticotropin-like intermediary peptide , corticotropin-lipotropin , melanotropin gamma , met-enkephalin , pro-opiomelanocortin , adrenocorticotropin , alpha-MSH , alpha-melanocyte-stimulating hormone , beta-LPH , beta-MSH , beta-melanocyte-stimulating hormone , gamma-LPH , gamma-MSH , lipotropin beta , lipotropin gamma , melanotropin alpha , melanotropin beta , opiomelanocortin prepropeptide , pro-ACTH-endorphin , proopiomelanocortin preproprotein , proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) , beta-lipotropin , beta-melanocyte stimulating hormone

18976 Mus musculus
5443 Homo sapiens
403659 Canis lupus familiaris
281416 Bos taurus
396863 Sus scrofa
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