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Adrenomedullin 2 Proteins (ADM2)

ADM2 encodes a protein which is a member of the calcitonin-related hormones. Additionally we are shipping Adrenomedullin 2 Antibodies (121) and Adrenomedullin 2 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Human ADM2 ADM2 79924 Q7Z4H4
Mouse ADM2 ADM2 223780 Q7TNK8
ADM2 399475 P61312
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Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Rat His tag 1 mg Log in to see 56 to 66 Days

ADM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

More Proteins for Adrenomedullin 2 (ADM2) Interaction Partners

Human Adrenomedullin 2 (ADM2) interaction partners

  1. Plasma intermedin and BNP levels were markedly higher in acute coronary syndrome patients than in healthy people.

  2. High levels of ADM2 expression predict a poorer survival in patients with pancreatic adenocarcinoma.

  3. TSH induced AM2/IMD expression in the thyroid gland and it could locally work as a potent vasodilator, resulting in the expansion of thyroid inter-follicular capillaries.

  4. Intermedin affects the endothelial cell junction and blood vessel sprouting in a VE-cadherin (show CDH5 Proteins) dependent way.

  5. results suggest that high plasma intermedin level is associated with poor outcomes of patients and may be a useful prognostic biomarker in ST-segment elevation acute myocardial infarction.

  6. ADM (show ADM Proteins) and IMD mRNA expression are elevated in chronic heart failure at different stages of the disease.

  7. a significant increase in plasma intermedin following acute myocardial infarction may be associated with oxidative stress, and could be used as a marker to reflect the severity of the coronary stenosis

  8. this study is the first to demonstrate a potential involvement of IMD in human embryo implantation and placental development via regulation of trophoblast invasion at the maternal-fetal interface

  9. Intermedin plays a critical role in the vascular remodeling process and tumor angiogenesis by regulating vascular endothelial-cadherin (show CDH5 Proteins) and extracellular signal-regulated kinase.

  10. adm2 polymorphism is associated with renal dysfunction, blood pressure regulation and asymptomatic cerebrovascular diseases in the Japanese general population

Mouse (Murine) Adrenomedullin 2 (ADM2) interaction partners

  1. IMD reduces bone resorption by inhibiting osteoblast apoptosis, decreasing the RANKL/OPG (show TNFSF11 Proteins) ratio and the expression of M-CSF (show CSF1R Proteins), and inhibiting osteoclast maturation and differentiation.

  2. Adrenomedullin-2/intermedin(8-47) ameliorates early ischemia/reperfusion injury in mouse lungs by protecting the integrity of the blood-air barrier and by potently reducing leukocyte influx into the alveolar space

  3. Intermedin attenuates macrophage foam-cell formation via tristetraprolin (show ZFP36 Proteins)-mediated degradation of CD36 (show CD36 Proteins) mRNA.

  4. increased stability of PTEN by intermedin leads to SR-A (show MSR1 Proteins) inhibition in macrophages, which ameliorates foam-cell formation and atherosclerosis in apoE (show APOE Proteins)(-/-) mice.

  5. Data show that mechanical ventilation reduced the expression of receptor activity-modifying protein RAMP3 (show RAMP3 Proteins), but not of intermedin (IMD), calcitonin receptor-like receptor (CRLR (show CALCRL Proteins)), and RAMP1 (show RAMP1 Proteins) and RAMP2 (show RAMP2 Proteins).

  6. Intermedin is a calcitonin/calcitonin (show CALCA Proteins) gene-related peptide (show CALCA Proteins) family peptide acting through the calcitonin receptor-like receptor (show CALCRL Proteins)/receptor activity-modifying protein receptor complexes

  7. Our data suggest that IMD acutely augments cardiomyocyte contractile function through, at least in part, a protein kinase C- and protein kinase A-dependent mechanism.

  8. tissue adrenomedullin 2 intermedin content was positively correlated with the diastolic blood pressure and negatively correlated with pulse pressure

  9. IMD is a novel hypoxia-induced gene and a potential interventional agent for the improvement of endothelial barrier function in systemic inflammatory responses and hypoxia-induced vascular leakage.

Adrenomedullin 2 (ADM2) Protein Profile

Protein Summary

This gene encodes a protein which is a member of the calcitonin-related hormones. The encoded protein is involved in maintaining homeostasis in many tissues, acting via CRLR/RAMP receptor (calcitonin receptor-like receptor/receptor activity-modifying protein) complexes. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with Adrenomedullin 2 Proteins (ADM2)

  • adrenomedullin 2a (adm2a)
  • adrenomedullin 2 (ADM2)
  • adrenomedullin 2 (am2)
  • adrenomedullin 2 (Adm2)
  • ADM2 protein
  • Am2 protein
  • dJ579N16.4 protein
  • Imd protein
  • Imdn protein
  • si:dkey-22l11.3 protein

Protein level used designations for Adrenomedullin 2 Proteins (ADM2)

adrenomedullin 2 , intermedin , adrenomedullin 2 precusor , ADM2

403114 Danio rerio
470251 Pan troglodytes
606919 Canis lupus familiaris
618896 Bos taurus
720666 Macaca mulatta
100125439 Oryzias latipes
79924 Homo sapiens
100517471 Sus scrofa
223780 Mus musculus
399475 Rattus norvegicus
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