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anti-Agouti Signaling Protein (ASIP) Antibodies

In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Additionally we are shipping Agouti Signaling Protein Proteins (27) and Agouti Signaling Protein Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASIP 434 P42127
Anti-Rat ASIP ASIP 24152 Q99JA2
ASIP 50518 Q03288
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Top anti-Agouti Signaling Protein Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated ELISA, WB 50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated ICC, IHC 50 μL Log in to see 8 to 10 Days
$1,013.83
Details
Human Rabbit Un-conjugated IF 50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB 200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC FACS, IHC, ELISA, WB 200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA, WB 200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP ELISA, WB 200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC ELISA, WB 200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB 200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Biotin ELISA, WB 200 μL Log in to see 16 Days
$710.29
Details

ASIP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


, , , , , ,
Mouse (Murine)


More Antibodies against Agouti Signaling Protein Interaction Partners

Cow (Bovine) Agouti Signaling Protein (ASIP) interaction partners

  1. Our results provide evidence for a widespread expression of ASIP in bovine tissues at mRNA and, for the first time, at protein level.

  2. Possible consequences of Abr (agouti gene mutated by insertion of LINE element)for meat and milk production in cattle.

Human Agouti Signaling Protein (ASIP) interaction partners

  1. Polymorphisms of ASIP were found to be associated with skin, hair, and eye color in a phenotypically diverse Brazilian population. More research is needed to determine its usefulness in forensic science.

  2. ASIP gene mutation is involved in the development of facial pigmented lesions.

  3. Data show that ASIP TG/TG (show TG Antibodies) diplotype, which is known to be associated with melanoma risk, was linked to a 5-fold increase in hazard of death from melanoma.

  4. An increased risk of melanoma (odds ratio [OR] 1.27, 95% confidence interval [95% CI] 1.03-1.57) in carriers of the rs4911414 variant, located 120 kb upstream of ASIP.

  5. By using a population-based material of high-risk melanoma cases, we demonstrate a significant effect of both MC1R (show MSHR Antibodies) red hair color (RHC (show RHCE Antibodies)) variants and an ASIP haplotype, but could not replicate an association with postulated risk SNPs of TYR (show TYR Antibodies) and TYRP1 (show TYRP1 Antibodies).

  6. Findings suggest that ASIP locus is associated with a number of non-melanoma skin cancers.

  7. Further analysis of binding and functional data suggests that the ASIP C-terminal loop (a six-amino-acid segment closed by the final disulfide bond) is essential for high-affinity MC1R binding and inverse agonism.

  8. polymorphism in the agouti signaling protein gene is associated with human pigmentation

  9. results show that men and women of similar age and BMI present similar agouti signal protein mRNA levels in omental and subcutaneous abdominal adipocytes but a sexual dimorphism exists in the relationship between its expression and BMI

  10. Results identify five genes that are down-regulated by agouti signalling protein (ASIP), indicating a likely role for ASIP in human melanogenesis.

Pig (Porcine) Agouti Signaling Protein (ASIP) interaction partners

  1. Mutational analysis of the ASIP loci in relation to coat color.

Horse (Equine) Agouti Signaling Protein (ASIP) interaction partners

  1. there was a correlation between the recessive ASIP allele and a more independent temperament

Mouse (Murine) Agouti Signaling Protein (ASIP) interaction partners

  1. Par-3 plays an important role in the modulation of intestinal barrier function by regulating delivery of occludin as well as suppression of MLC phosphorylation.

  2. HTT (show HTT Antibodies) is required for the apical localization of PAR3 (show F2RL2 Antibodies)-aPKC during epithelial morphogenesis in virgin, pregnant, and lactating mice.

  3. Methylation analysis reveals that although most lines display normal methylation at IAP (show ALPI Antibodies) elements in general, the Avy IAP (show ALPI Antibodies) element is essentially unmethylated.

  4. Authors identify the cell polarity protein Par3, a negative regulator of neuronal differentiation, as a Smek1 (show SMEK1 Antibodies) substrate and demonstrate that Smek1 (show SMEK1 Antibodies) suppresses its activity.

  5. Par3 (show F2RL2 Antibodies) (and protein kinase C zeta (show PRKCZ Antibodies)) are activated in neurons when binding to N2-proteoglygan.

  6. Suggest that loss of Par3 (show F2RL2 Antibodies) promotes metastatic behaviour of ErbB2 (show ERBB2 Antibodies)-induced breast tumour epithelial cells by decreasing cell-cell cohesion.

  7. Par3 (show F2RL2 Antibodies) is identified as a regulator of signaling pathways relevant to invasive breast cancer.

  8. The nucleus of a myoblast moves rapidly after fusion towards the central myotube nuclei which is driven by microtubules and dynein/dynactin (show DCTN1 Antibodies) complex, and requires Cdc42 (show CDC42 Antibodies), Par6 (show PARD6A Antibodies) and Par3 (show F2RL2 Antibodies).

  9. Data suggest that aPKC phosphorylates JAM-A (show F11R Antibodies) at S285 to regulate cell-cell contact maturation, TJ formation, and single lumen specification.

  10. Brain-derived neurotrophic factor (BDNF (show BDNF Antibodies)) induces polarized signaling of small GTPase (show RACGAP1 Antibodies) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (show F2RL2 Antibodies)) protein.

Agouti Signaling Protein (ASIP) Antigen Profile

Protein Summary

In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Gene names and symbols associated with ASIP

  • agouti signaling protein (ASIP) antibody
  • agouti signaling protein, nonagouti homolog (mouse) (ASIP) antibody
  • agouti signaling protein (asip) antibody
  • agouti signaling protein (Asip) antibody
  • agouti-signaling protein-like (LOC709156) antibody
  • nonagouti (a) antibody
  • par-3 (partitioning defective 3) homolog (C. elegans) (Pard3) antibody
  • A antibody
  • AA960621 antibody
  • AGSW antibody
  • AGTI antibody
  • AGTIL antibody
  • AI256638 antibody
  • As antibody
  • ASIP antibody
  • ASP antibody
  • D8Ertd580e antibody
  • PAR-3 antibody
  • Par3 antibody
  • Pard3a antibody
  • SHEP9 antibody

Protein level used designations for ASIP

agouti signaling protein, nonagouti homolog , agouti-signaling protein , agouti signaling protein , ASP , agouti switch protein , nonagouti homolog , agouti signalling protein , Agouti (coat color) , agouti-signaling protein-like , Agouti switch protein , Agouti-signaling protein , agouti coat color protein , agouti signal protein , non-agouti , PARD-3 , PHIP , atypical PKC isotype-specific-interacting protein , ephrin-interacting protein , partitioning defective 3 homolog

GENE ID SPECIES
100440302 Pongo abelii
419147 Gallus gallus
100144328 Oryctolagus cuniculus
100302661 Papio anubis
100431176 Oncorhynchus mykiss
100218186 Taeniopygia guttata
100032347 Monodelphis domestica
404192 Bos taurus
492296 Canis lupus familiaris
434 Homo sapiens
414439 Sus scrofa
24152 Rattus norvegicus
100974762 Pan paniscus
747368 Pan troglodytes
100054335 Equus caballus
100401359 Callithrix jacchus
492297 Felis catus
709156 Macaca mulatta
50518 Mus musculus
93742 Mus musculus
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