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anti-Ajuba LIM Protein (AJUBA) Antibodies

cytoplasmic LIM protein that binds glial glutamate transporter GLT-1 and is proposed to allow glial glutamate transporter GLT-1 to regulate intracellular signaling or interact with the cytoskeleton. Additionally we are shipping AJUBA Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AJUBA 84962 Q96IF1
AJUBA 16475 Q91XC0
AJUBA 85265 Q5U2Z2
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Top anti-AJUBA Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Affinity Purified anti-Ajuba antibody shows detection of Ajuba-RFP fusion protein in cell lysates (arrow-head).  Lanes correspond to 1) vector only trans-fection, 2) human Ajuba-RFP, 3) mouse Ajuba-RFP, and 4) mock transfection. Approximately 50 µg of each lysate was loaded per lane for SDS-PAGE followed by transfer onto nitrocellulose and reaction with a 1:1,700 dilution of anti-Ajuba antibody.  Detection occurred using a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] (611-132-122) for 45 min at room temperature (800 nm channel, green).  Molecular weight estimation was made by comparison to prestained MW markers (indicated at left, 700 nm channel, red).  IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc.  Other detection systems will yield similar results. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Human Mouse Un-conjugated IP, WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Human Mouse Un-conjugated WB Western Blot analysis of JUB expression in transfected 293T cell line by JUB MaxPab polyclonal antibody.Lane 1: JUB transfected lysate(59.18 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated FACS, IP, WB   100 μL Log in to see 8 to 10 Days
$683.83
Details
Human Goat Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$1,167.83
Details
Human Rabbit Un-conjugated IHC, ELISA   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated IP, ELISA, WB   100 μg Log in to see 11 to 16 Days
$707.14
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 11 to 16 Days
$553.14
Details

AJUBA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
, ,
,
Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-AJUBA Antibodies

  1. Dog (Canine) Polyclonal AJUBA Primary Antibody for EIA, WB - ABIN401292 : Hirota, Kunitoku, Sasayama, Marumoto, Zhang, Nitta, Hatakeyama, Saya: Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. in Cell 2003 (PubMed)
    Show all 2 references for ABIN401292

More Antibodies against AJUBA Interaction Partners

Human Ajuba LIM Protein (AJUBA) interaction partners

  1. The results in this study uncovered that JUB was a regulator involved in proliferation of glioma cells, and it could be used as a potential therapeutic target for glioma.

  2. AJUBA negatively regulates YAP activity through the LATS family, and inactivation of AJUBA is a novel key mechanism in malignant mesothelioma cell proliferation

  3. the LIM protein JUB serves as a tumor-promoting gene in colorectal cancer by promoting epithelial-mesenchymal transition, a critical process of metastasis.

  4. The LIM (show PDLIM5 Antibodies) domain of Ajuba can competitively bind to the N-terminal of Aurora-A (show AURKA Antibodies), and inhibited the interaction between N-terminal and C-terminal of Aurora A (show AURKA Antibodies).

  5. A Rac-PAK1-Ajuba feedback loop integrates spatiotemporal signaling with actin remodeling at cell-cell contacts and stabilizes preassembled cadherin complexes.

  6. Ajuba contains functional nuclear-receptor interacting motifs and selectively interacts with retinoic acid receptors and rexinoid receptor subtypes.

  7. Ajuba contributes to the bridging of the cadherin adhesive complexes to the actin cytoskeleton and as such contribute to the formation or strengthening of cadherin-mediated cell-cell adhesion.

  8. in addition to its effects upon Rac activity, Ajuba can also influence cell migration through regulation of PI(4,5)P2 synthesis through direct activation of PIPKIalpha enzyme activity

  9. Ajuba is a new cytosolic component of the IL-1 signaling pathway modulating IL-1-induced NF-kappaB activation b (show IL1A Antibodies)y influencing the assembly and activity of the aPKC/p62/TRAF6 multiprotei (show GTF2H1 Antibodies)n sign (show TRAF6 Antibodies)aling complex

  10. Ajuba promoted GSK-3beta (show GSK3b Antibodies)-mediated phosphorylation of beta-catenin (show CTNNB1 Antibodies) by reinforcing the association between beta-catenin (show CTNNB1 Antibodies) and GSK-3beta (show GSK3b Antibodies).

Mouse (Murine) Ajuba LIM Protein (AJUBA) interaction partners

  1. Ajuba recruits p300/CBP (show CREBBP Antibodies) via its LIM (show PDLIM5 Antibodies) domain and facilitates p300/CBP (show CREBBP Antibodies) binding to PPARg (show PPARG Antibodies). Moreover, Ajuba, PPARg (show PPARG Antibodies), p300/CBP (show CREBBP Antibodies) can cooperatively occupy the PPARg (show PPARG Antibodies) target promoters and concomitantly increases histone acetylation at these loci.

  2. Ajuba is a novel coactivator for liver X receptors and may play important role in lipid and glucose metabolism.

  3. Findings support the importance of adhesion molecules (VE-cadherin and CD31), survivin, and Ajuba in modulating the Hippo pathway, which regulates, in part, proliferation and survival in hemangioendotheliomas.

  4. PKD1-mediated phosphorylation of SNAI1 occurs in the nucleus and generates a nuclear, inactive DNA/SNAI1 complex that shows decreased interaction with its co-repressor Ajuba.

  5. This paper presents evidence indicating that the human and mouse Ajuba is a new cytosolic component of the IL-1 (show IL1A Antibodies) signaling pathway, influencing the assembly and activity of the aPKC/p62 (show GTF2H1 Antibodies)/TRAF6 (show TRAF6 Antibodies) multiprotein signaling complex.

  6. identification of the protein arginine methyltransferase 5 (PRMT5 (show PRMT5 Antibodies)) as an effector recruited to SNAIL (show SNAI1 Antibodies) through an interaction with AJUBA that functions to repress the SNAIL (show SNAI1 Antibodies) target gene, E-cadherin (show CDH1 Antibodies)

AJUBA Antigen Profile

Protein Summary

cytoplasmic LIM protein that binds glial glutamate transporter GLT-1 and is proposed to allow glial glutamate transporter GLT-1 to regulate intracellular signaling or interact with the cytoskeleton

Gene names and symbols associated with AJUBA

  • ajuba LIM protein (AJUBA) antibody
  • ajuba LIM protein (Ajuba) antibody
  • jub, ajuba homolog (Xenopus laevis) (AJUBA) antibody
  • Jub antibody

Protein level used designations for AJUBA

LIM domain-containing protein ajuba , jub, ajuba homolog , protein ajuba , Ajuba protein , ajuba homolog

GENE ID SPECIES
84962 Homo sapiens
480244 Canis lupus familiaris
16475 Mus musculus
85265 Rattus norvegicus
519937 Bos taurus
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