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anti-Alanine Glyoxylate Aminotransferase (AGXT) Antibodies

AGXT is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Additionally we are shipping Alanine Glyoxylate Aminotransferase Proteins (8) and Alanine Glyoxylate Aminotransferase Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGXT 189 P21549
AGXT 11611 O35423
AGXT 24792 P09139
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Top anti-Alanine Glyoxylate Aminotransferase Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of AGXT Antibody (Center) (ABIN390393) in HepG2 cell line lysates (35 µg/lane). AGXT (arrow) was detected using the purified polyclonal antibody.(8 µg/mL) AGXT Antibody (Center) (ABIN390393) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IF 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated IF, ELISA Immunofluorescenitrocellulosee of human HeLa cells stained with PI (Red) and monoclonal anti-AGXT antibody (1:500) with Alexa 488 (Green). 100 μL Log in to see 3 to 4 Days
$376.79
Details
Mouse Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC (p) Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated IHC 0.05 mL Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 14 Days
$369.79
Details

AGXT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Alanine Glyoxylate Aminotransferase Antibodies

  1. Human Monoclonal AGXT Primary Antibody for EIA, IF - ABIN452656 : Donini, Ferrari, Fedeli, Faini, Lamberto, Marletta, Mellini, Panini, Percudani, Pollegioni, Caldinelli, Petrucco, Peracchi: Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism. in The Biochemical journal 2009 (PubMed)
    Show all 3 references for ABIN452656

  2. Human Polyclonal AGXT Primary Antibody for EIA, WB - ABIN452724 : Cellini, Montioli, Paiardini, Lorenzetto, Voltattorni: Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN452724

  3. Human Polyclonal AGXT Primary Antibody for FACS, IHC (p) - ABIN390393 : Bertoldi, Cellini, Paiardini, Montioli, Borri Voltattorni: Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis. in Biochimica et biophysica acta 2008 (PubMed)
    Show all 2 references for ABIN390393

More Antibodies against Alanine Glyoxylate Aminotransferase Interaction Partners

Human Alanine Glyoxylate Aminotransferase (AGXT) interaction partners

  1. Letter/Case Report: novel missense AGXT gene mutation in a Sri (show SRI Antibodies) Lankan family with primary hyperoxaluria type 1.

  2. Primary hyperoxaluria type 1 (PH1) is due to a defect in the AGXT gene. The aim of our study was to analyze the mutations causing PH1 in the Moroccan population

  3. The pathogenic mutation G47R causes misfolding of alanine:glyoxylate aminotransferase.

  4. A review of the current knowledge of the biochemical properties of liver peroxisomal alanine:glyoxylate aminotransferase and of the molecular defects caused by single point mutations associated with Primary Hyperoxaluria Type 1.

  5. S81L and G170R mutations of AGT is associated with Primary Hyperoxaluria type I in homozygosis and heterozygosis.

  6. AGT missense mutations associated with Primary Hyperoxaluria Type 1, were characterized.

  7. Data suggest that dequalinium chloride (DECA) may be a pharmacologic strategy to treat primary hyperoxaluria 1 (PH1) patients with mutations in alanine:glyoxylate aminotransferase (AGT).

  8. These are the first cases of primary hyperoxaluria type 1 to be diagnosed by clinical manifestations and AGXT gene mutations in mainland China.

  9. data imply that the AGT Pro11Leu polymorphism is not directly responsible for the low incidence of stone formation in black South Africans.

  10. Modeling of the mutations on a 1.9 A crystal structure suggests that Primary hyperoxaluria type I causing mutants perturb locally the native structure of AGT.

Mouse (Murine) Alanine Glyoxylate Aminotransferase (AGXT) interaction partners

  1. expressed wild-type human AGT1 was predominantly localized in mouse hepatocellular peroxisomes, whereas the most common mutant form of AGT1 (G170R) was localized predominantly in the mitochondria

Alanine Glyoxylate Aminotransferase (AGXT) Antigen Profile

Protein Summary

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

Gene names and symbols associated with AGXT

  • alanine-glyoxylate aminotransferase (AGXT) antibody
  • alanine-glyoxylate aminotransferase (Agxt) antibody
  • AGT antibody
  • Agt1 antibody
  • Agxt1 antibody
  • PH1 antibody
  • Spat antibody
  • SPT antibody
  • TLH6 antibody

Protein level used designations for AGXT

L-alanine: glyoxylate aminotransferase 1 , alanine--glyoxylate aminotransferase , hepatic peroxisomal alanine:glyoxylate aminotransferase , serine--pyruvate aminotransferase , serine-pyruvate aminotransferase , serine:pyruvate aminotransferase , alanine-glyoxylate aminotransferase 1 , serine--pyruvate aminotransferase, mitochondrial , serine--pyruvate aminotransferase, peroxisomal , angiotensin receptor 2 , serine:pyruvate aminotransferase SPT , serine:pyruvate/alanine:glyoxylate aminotransferase , AGT , SPT , alanine:glyoxylate aminotransferase

GENE ID SPECIES
189 Homo sapiens
11611 Mus musculus
24792 Rattus norvegicus
727692 Felis catus
100009147 Oryctolagus cuniculus
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