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Alanine Glyoxylate Aminotransferase Proteins (AGXT)

AGXT is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Additionally we are shipping Alanine Glyoxylate Aminotransferase Antibodies (84) and Alanine Glyoxylate Aminotransferase Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AGXT 189 P21549
AGXT 11611 O35423
Rat AGXT AGXT 24792 P09139
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Top Alanine Glyoxylate Aminotransferase Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$3,059.83
Details
Yeast Cat His tag   1 mg Log in to see 56 to 66 Days
$3,080.00
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,081.83
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 11 to 12 Days
$362.88
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

AGXT Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Alanine Glyoxylate Aminotransferase (AGXT) Interaction Partners

Human Alanine Glyoxylate Aminotransferase (AGXT) interaction partners

  1. Letter/Case Report: novel missense AGXT gene mutation in a Sri (show SRI Proteins) Lankan family with primary hyperoxaluria type 1.

  2. Primary hyperoxaluria type 1 (PH1) is due to a defect in the AGXT gene. The aim of our study was to analyze the mutations causing PH1 in the Moroccan population

  3. The pathogenic mutation G47R causes misfolding of alanine:glyoxylate aminotransferase (show AGT Proteins).

  4. A review of the current knowledge of the biochemical properties of liver peroxisomal alanine:glyoxylate aminotransferase (show AGT Proteins) and of the molecular defects caused by single point mutations associated with Primary Hyperoxaluria Type 1.

  5. S81L and G170R mutations of AGT is associated with Primary Hyperoxaluria type I in homozygosis and heterozygosis.

  6. AGT missense mutations associated with Primary Hyperoxaluria Type 1, were characterized.

  7. Data suggest that dequalinium chloride (DECA) may be a pharmacologic strategy to treat primary hyperoxaluria 1 (PH1) patients with mutations in alanine:glyoxylate aminotransferase (AGT (show AGT Proteins)).

  8. These are the first cases of primary hyperoxaluria type 1 to be diagnosed by clinical manifestations and AGXT gene mutations in mainland China.

  9. data imply that the AGT Pro11Leu polymorphism is not directly responsible for the low incidence of stone formation in black South Africans.

  10. Modeling of the mutations on a 1.9 A crystal structure suggests that Primary hyperoxaluria type I causing mutants perturb locally the native structure of AGT.

Mouse (Murine) Alanine Glyoxylate Aminotransferase (AGXT) interaction partners

  1. expressed wild-type human AGT1 was predominantly localized in mouse hepatocellular peroxisomes, whereas the most common mutant form of AGT1 (G170R) was localized predominantly in the mitochondria

Alanine Glyoxylate Aminotransferase (AGXT) Protein Profile

Protein Summary

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

Gene names and symbols associated with AGXT

  • alanine-glyoxylate aminotransferase (AGXT)
  • alanine-glyoxylate aminotransferase (Agxt)
  • AGT protein
  • Agt1 protein
  • Agxt1 protein
  • PH1 protein
  • Spat protein
  • SPT protein
  • TLH6 protein

Protein level used designations for AGXT

L-alanine: glyoxylate aminotransferase 1 , alanine--glyoxylate aminotransferase , hepatic peroxisomal alanine:glyoxylate aminotransferase , serine--pyruvate aminotransferase , serine-pyruvate aminotransferase , serine:pyruvate aminotransferase , alanine-glyoxylate aminotransferase 1 , serine--pyruvate aminotransferase, mitochondrial , serine--pyruvate aminotransferase, peroxisomal , angiotensin receptor 2 , serine:pyruvate aminotransferase SPT , serine:pyruvate/alanine:glyoxylate aminotransferase , AGT , SPT , alanine:glyoxylate aminotransferase

GENE ID SPECIES
189 Homo sapiens
11611 Mus musculus
24792 Rattus norvegicus
727692 Felis catus
100009147 Oryctolagus cuniculus
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