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The protein encoded by AARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Additionally we are shipping AARS2 Proteins (3) and AARS2 Kits (1) and many more products for this protein.
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Human Polyclonal AARS2 Primary Antibody for FACS, IHC (p) - ABIN391806
Bonnefond, Fender, Rudinger-Thirion, Giegé, Florentz, Sissler: Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. in Biochemistry 2005
A new phenotype caused by AARS2 mutations is characterized by leukoencephalopathy and ovarian failure in female patients, indicating that the phenotypic spectrum associated with AARS2 variants is much wider than previously reported.
Mutations in AARS2 found in lethal mitochondrial myopathy
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
probable alanyl-tRNA synthetase, mitochondrial
, alanyl-tRNA synthetase like
, alanyl-tRNA synthetase 2, mitochondrial (putative)
, alanyl-tRNA synthetase, mitochondrial
, alanine tRNA ligase 2, mitochondrial (putative)
, alanine--tRNA ligase, mitochondrial