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Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide Proteins (ADH1A)

ADH1A encodes a member of the alcohol dehydrogenase family. Additionally we are shipping ADH1A Antibodies (35) and ADH1A Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADH1A 11522 P00329
Rat ADH1A ADH1A 24172 P06757
ADH1A 124 P07327
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Top ADH1A Proteins at

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
Yeast Uromastyx hardwickii His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

ADH1A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,

Top referenced ADH1A Proteins

  1. Human ADH1A Protein expressed in Escherichia coli (E. coli) - ABIN667689 : Jelski, Chrostek, Laszewicz, Szmitkowski: Alcohol dehydrogenase (ADH) isoenzyme activity in the sera of patients with Helicobacter pylori infection. in Digestive diseases and sciences 2007 (PubMed)
    Show all 2 references for ABIN667689

  2. Human ADH1A Protein expressed in Wheat germ - ABIN1305977 : Mutka, Green, Verderber, Richards, Looker, Chlipala, Rosenthal: ADH IB expression, but not ADH III, is decreased in human lung cancer. in PLoS ONE 2013 (PubMed)
    Show all 2 references for ABIN1305977

More Proteins for Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) Interaction Partners

Mouse (Murine) Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) interaction partners

  1. Overexpression of an ADH1 transgene protected against tunicamycin-induced cardiac dysfunction through attenuation of ER stress, oxidative stress, and PTEN-Akt (show AKT1 Proteins)-mTOR (show FRAP1 Proteins) regulated autophagy.

  2. Data indicate a potential change in aldehyde dehydrogenase (ALDH) activity of proliferating beta cells during pregnancy.

  3. This study demonistrated that adh1 knockout mice as possible rodent models for presymptomatic Parkinson's disease.

  4. Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

  5. Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase (show AKR1A1 Proteins)

  6. ADH1 functions as the primary enzyme responsible for efficient oxidative clearance of excess retinol, thus providing protection and increased survival during vitamin A toxicity

  7. Crbp1 (show RBP1 Proteins)-/- mice also exhibited increased metabolism of a dose of retinol into retinoic acid, and this increased metabolism was not observed in Crbp1 (show RBP1 Proteins)-/-/Adh1-/- mice

  8. Cellular expression of Adh1 in the GI tract was studied.

  9. After chronic ethanol consumption, the activity of the MEOS increases, with an associated rise in cytochrome P450, especially CYP2E1 (show CYP2E1 Proteins), most conclusively shown in alcohol dehydrogenase (show AKR1A1 Proteins) negative deer mice.

  10. Liver disease in the alcoholic is due not only to malnutrition but also to ethanol's hepatotoxicity linked to its metabolism by means of the alcohol dehydrogenase (show AKR1A1 Proteins) and CYP2E1 (show CYP2E1 Proteins) pathways and the resulting production of toxic acetaldehyde.

Human Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) interaction partners

  1. Data indicate that the up-regulation of aldehyde dehydrogenase-1 (ALDH1) after neoadjuvant chemotherapy (NAC) predicts poor survival in locally advanced breast cancer.

  2. Unde-rexpression of the ADH1 gene, which influences the transformation of the extracellular matrix, plays a probable role in the etiology of uterine fibroid.

  3. high levels of ADH1 transcription are implicated in fluconazole resistance in C. albicans and that the mRNA expression levels of ADH1 are positively correlated with those of CDR1, CDR2 and FLU1.

  4. common ADH (show AVP Proteins) variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  5. High ADH1 is associated with endometrial cancer.

  6. ADH1A variation predisposes to personality traits and substance dependence

  7. GATA-2 (show GATA2 Proteins) and HNF-3beta (show FOXA2 Proteins) regulate the human alcohol dehydrogenase 1A (ADH1A) gene.

  8. The oxidative pathway of ethanol metabolism via ADH and ALDH does not play a role in pancreatic carcinogenesis.

  9. Alleles of ADH7 SNPs were associated with the early stages of alcohol metabolism, with additional effects in the ADH1A, ADH1B and ADH4 regions.

ADH1A Protein Profile

Protein Summary

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Gene names and symbols associated with ADH1A

  • alcohol dehydrogenase 1 (adh1)
  • alcohol dehydrogenase 1A (class I), alpha polypeptide (ADH1A)
  • alcohol dehydrogenase ADH1 (ADH1)
  • Alcohol dehydrogenase 1 (Dvir\\Adh1)
  • alcohol dehydrogenase 1 (class I) (Adh1)
  • ADC1 protein
  • Adh protein
  • Adh-1 protein
  • Adh-1-t protein
  • Adh-1e protein
  • Adh-1t protein
  • Adh-3e protein
  • ADH-AA protein
  • ADH1 protein
  • Adh1-e protein
  • Adh1-t protein
  • Adh1a protein
  • Adh1c protein
  • Adh1tl protein
  • Adh3-e protein
  • AI194826 protein
  • Dvir\\Adh protein
  • Dvir\\GJ18208 protein
  • dvir_GLEANR_2771 protein
  • GJ18208 protein

Protein level used designations for ADH1A

class I alcohol dehydrogenase, alpha subunit , Adh1-PA , Dvir\\Adh1-PA , Dvir\\GJ18208-PA , GJ18208-PA , alcohol dehydrogenase , alcohol dehydrogenase 1 , ADH-A2 , alcohol dehydrogenase 1 temporal, liver , alcohol dehydrogenase 1, complex , alcohol dehydrogenase 1, electrophoretic , alcohol dehydrogenase 3, electrophoretic , alcohol dehydrogenase A subunit , class I alcohol dehydrogenase , alcohol dehydrogenase (class I), alpha polypeptide , alcohol dehydrogenase 1C (class I), gamma polypeptide , ADH, alpha subunit , alcohol dehydrogenase 1 (class I), alpha polypeptide , alcohol dehydrogenase 1A , alcohol dehydrogenase subunit alpha , aldehyde reductase , alcohol dehydrogenase 1 (subunit A) , alchohol dehydrogenase 1A

496861 Xenopus (Silurana) tropicalis
744064 Pan troglodytes
854068 Saccharomyces cerevisiae S288c
6634390 Drosophila virilis
11522 Mus musculus
24172 Rattus norvegicus
124 Homo sapiens
280982 Bos taurus
100009283 Oryctolagus cuniculus
707682 Macaca mulatta
100172370 Pongo abelii
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