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anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Antibodies

ADH5 encodes a member of the alcohol dehydrogenase family. Additionally we are shipping Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Proteins (30) and Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADH5 128 P11766
ADH5 11532 P28474
ADH5 100145871 P12711
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Top anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ADH5 Antibody (Center) (ABIN652502) in K562 cell line lysates (35 µg/lane). ADH5 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADH5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ADH5 Antibody (Center) in K562 cell line lysates (35ug/lane). ADH5 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ADH5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human kidney WB Suggested Anti-ADH5  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Arabidopsis thaliana Rabbit Un-conjugated WB 50 μL Log in to see 5 to 6 Days
$375.38
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using ADH5 antibody. Immunofluorescence analysis of HepG2 cell using ADH5 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 9 Days
$302.50
Details

ADH5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Antibodies

  1. Human Polyclonal ADH5 Primary Antibody for EIA, WB - ABIN453501 : Martins-de-Souza, Gattaz, Schmitt, Rewerts, Maccarrone, Dias-Neto, Turck: Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. in European archives of psychiatry and clinical neuroscience 2009 (PubMed)
    Show all 2 references for ABIN453501

  2. Mouse (Murine) Polyclonal ADH5 Primary Antibody for ELISA, WB - ABIN190868 : Adinolfi, Adinolfi, Hopkinson: Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme. in Annals of human genetics 1984 (PubMed)

  3. Human Polyclonal ADH5 Primary Antibody for FACS, IHC (p) - ABIN652502 : Iborra, Renau-Piqueras, Portoles, Boleda, Guerri, Pares: Immunocytochemical and biochemical demonstration of formaldhyde dehydrogenase (class III alcohol dehydrogenase) in the nucleus. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992 (PubMed)

  4. Arabidopsis thaliana Polyclonal ADH5 Primary Antibody for WB - ABIN488639 : Lee, Wie, Fernandez, Feelisch, Vierling: Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis. in The Plant cell 2008 (PubMed)

More Antibodies against Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Interaction Partners

Fruit Fly (Drosophila melanogaster) Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) interaction partners

Human Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) interaction partners

  1. GSNOR expression has different effect on neuronal viability in dependence on the stimulus applied, and plays opposite roles in SH-SY5Y models of Parkinson's disease and amyotrophic lateral sclerosis

  2. ADH5 counteracts neuronal differentiation of neural stem cells and this effect can be reversed by pharmacological inhibition of ADH5.

  3. common ADH (show AVP Antibodies) variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  4. A decrease in ADH (show AVP Antibodies) IB, rather than GSNOR, correlates with human lung cancer.

  5. study compared individuals occupationally exposed to formaldehyde and controls to effects of XRCC3 (show XRCC3 Antibodies) Thr241Met, ADH5 Val309Ile and Asp353Glu polymorphisms; ADH5 polymorphisms did not show significant association with genotoxicity biomarkers

  6. Data suggest that GSNOR deficiency, through dysregulated S-nitrosylation, may promote hepatocellular carcinoma, possibly by inactivating a DNA repair system.

  7. Significant associations were found however, for reactions to alcohol with a SNP in ADH5 (rs6827292, p = .001) and a SNP just upstream of ADH5 (rs6819724, p = .0007) that is in strong LD with rs6827292.

  8. POZ domain of FBI1 (show ZBTB7A Antibodies) represses transcription of ADH5.

  9. The structural determination of apo (show C9orf3 Antibodies), binary alcohol, and inhibitory ternary FDH complexes provides new insight into the enzyme's metal-assisted catalysis and substrate-binding properties.

  10. Formation of a FDH-S-(hydroxymethyl)glutathione-NADH ternary complex causes movement of glutathione-dependent formaldehyde dehydrogenase catalytic domain toward the coenzyme-binding domain, and a change in active-site zinc coordination.

Mouse (Murine) Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) interaction partners

  1. Loss of GSNOR confers enhanced post-MI cardiac regenerative activity, characterized by enhanced turnover of cardiomyocytes and cardiac stem cells.

  2. Results show that ADH5 removes endogenous formaldehyde to prevent DNA adducts, and protects with FANCD2 (show FANCD2 Antibodies), hematopoietic stem cells, hepatocytes, and nephrons from endogenous DNA damage.

  3. S-nitrosoglutathione reductase-dependent modification of PPARgamma (show PPARG Antibodies) alters the balance between adipocyte and osteoblast differentiation and provides checkpoint regulation of the lineage bifurcation of these 2 lineages.

  4. These findings provide novel insights into the involvement of GSNOR and S-nitrosylation in neuromuscular atrophy and neuropathic pain that are associated with pathological states.

  5. Overexpression of ADH5 reduces both development and adult neuronal differentiation of neurons. This effect depends on the catalytic activity of ADH5 and involves ADH5-mediated denitrosation of histone deacetylase 2 (HDAC2 (show HDAC2 Antibodies)).

  6. GSNOR appears to play a crucial role in controlling pulmonary and systemic infection by K. pneumoniae.

  7. A critical role for GSNOR in maintaining genomic integrity.

  8. This study suggests that S-nitrosoglutathione reductase degradation of S-nitrosoglutathione is a vital step in the expression of ventilatory roll-off

  9. GSNOR deficiency has a role in hepatocarcinogenesis, which is prevented by iNOS (show NOS2 Antibodies) inhibition

  10. Increasing the denitrosylation capacity of cardiomyocytes, via cardiomyocyte-specific overexpression of GSNOR, protects against sepsis-induced myocardial depression.

Arabidopsis thaliana Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) interaction partners

  1. polar auxin transport was compromised in gsnor1-3, which was correlated with universally reduced levels of PIN (show DYNLL1 Antibodies) or GFP-PIN (show DYNLL1 Antibodies) proteins in the roots of the mutant.

  2. Collectively, our findings imply that AtGSNOR1 controls multiple genetic networks integral to plant growth and development.

  3. Taken together, these results suggest that GSNOR1/HOT5/PAR2 plays an important role in regulating cell death in plant cells through modulating intracellular NO level.

  4. S-nitrosoglutathione reductase is an important and widely utilized component of pathogen resistance protein signaling networks conserved in animals and plants.

Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Antigen Profile

Protein Summary

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Gene names and symbols associated with ADH5

  • Formaldehyde dehydrogenase (Fdh) antibody
  • alcohol dehydrogenase 5 (adh5) antibody
  • Alcohol dehydrogenase class-3 (RSKD131_0888) antibody
  • Alcohol dehydrogenase class-3 (adhI) antibody
  • Alcohol dehydrogenase class-3 (adhx) antibody
  • alcohol dehydrogenase 2; same as cosmid orf Ca41C10.04; similar to C. albicans ADH1 (CaP19.3997), P.stipitis ADH2 and S. cerevisiae ADH2 (ADH2) antibody
  • alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) antibody
  • alcohol dehydrogenase 5 (class III), chi polypeptide (Adh5) antibody
  • alcohol dehydrogenase class-3 (HOT5) antibody
  • formaldehyde dehydrogenase homolog1 (fdh1) antibody
  • ADH-3 antibody
  • Adh-5 antibody
  • ADH1C antibody
  • ADH2 antibody
  • Adh3 antibody
  • ADHX antibody
  • ADHX_DROME antibody
  • ALCOHOL DEHYDROGENASE 2 antibody
  • ATGSNOR1 antibody
  • CG6598 antibody
  • Dmel\\CG6598 antibody
  • FALDH antibody
  • FDH antibody
  • gfd antibody
  • gfd/odh antibody
  • GLUTATHIONE-DEPENDENT FORMALDEHYDE DEHYDROGENASE antibody
  • GSH-FDH antibody
  • GSNOR antibody
  • MRH10.4 antibody
  • MRH10_4 antibody
  • odh antibody
  • PAR2 antibody
  • PARAQUAT RESISTANT 2 antibody
  • S-NITROSOGLUTATHIONE REDUCTASE antibody
  • sensitive to hot temperatures 5 antibody
  • wu:fb60b11 antibody

Protein level used designations for ADH5

CG6598-PA , Fdh-PA , formaldehyde dehydrogenase , glutathione-dependent formaldehyde dehydrogenase , octanol dehydrogenase , alcohol dehydrogenase class-3 , fb60b11 , Alcohol dehydrogenase class-3 , hypothetical protein , S-(hydroxymethyl)glutathione dehydrogenase , alcohol dehydrogenase (class III), chi polypeptide , alcohol dehydrogenase class chi chain , alcohol dehydrogenase class-III , ADH-B2 , FALDH , FDH , GSH-FDH , S-nitrosoglutathione reductase , alcohol dehydrogenase 2 , alcohol dehydrogenase B2 , class III alcohol dehydrogenase, chi subunit , alcohol dehydrogenase 1C (class I), gamma polypeptide , class III alcohol dehydrogenase , CL1875_1 , CL1875_1_ov , CL1875_1b , IDP332 , fadh1 , glutothione-dependent formaldehyde dehydrogenase

GENE ID SPECIES
41311 Drosophila melanogaster
116517 Danio rerio
7360621 Rhodobacter sphaeroides KD131
9416150 Ralstonia solanacearum CFBP2957
100195992 Salmo salar
3640833 Candida albicans SC5314
128 Homo sapiens
11532 Mus musculus
505515 Bos taurus
100145871 Rattus norvegicus
100009307 Oryctolagus cuniculus
834417 Arabidopsis thaliana
542459 Zea mays
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