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Aldehyde Dehydrogenase 1 Family, Member L1 Proteins (ALDH1L1)

The protein encoded by ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. Additionally we are shipping ALDH1L1 Antibodies (88) and ALDH1L1 Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALDH1L1 10840 O75891
ALDH1L1 107747 Q8R0Y6
Rat ALDH1L1 ALDH1L1 64392 P28037
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Top ALDH1L1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ALDH1L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) Interaction Partners

Zebrafish Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) interaction partners

  1. The crystal structures of apo (show C9orf3 Proteins)-form N-terminal domain - FDH and its complexes with the substrate analogue 10-formyl-5,8-dideazafolate (10-FDDF) and with the products tetrahydrofolate and formate have been determined.

  2. Knock-down of the fdh(10-Formyltetrahydrofolate dehydrogenase) gene impeded morphogenetic movement and caused incorrect cardiac positioning, defective hematopoiesis, notochord malformation and ultimate death of morphants

Human Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) interaction partners

  1. Data suggest that isoforms of FTHFD occur both in mitochondria and in cytosol; activity of cytosolic FTHFD appears to respond to supply of one-carbon groups in excess (show RCC1 Proteins) of those required for classical one-carbon metabolism. [REVIEW]

  2. JNK1 (show MAPK8 Proteins)/2 phosphorylate Bid (show BID Proteins) at Thr59 within the caspase (show CASP3 Proteins) cleavage site in response to ALDH1L1.

  3. ALDH1 (show ALDH1A1 Proteins) is indicative of stemness and is a biomarker marker in colon cancer.

  4. one variant in the ALDH1L1 locus, rs2364368, was associated with incident ischemic stroke.

  5. The results in this study, for the first time, reveal that the mRNA and protein expressions of ALDH1L1 are significantly reduced in hepatocellular carcinoma tissues

  6. Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.

  7. These studies support ALDH1L1 as a general CNS astroglial marker.

  8. inhibition of cell motility by ALDH1L1 associated with dephosphorylation of the actin depolymerizing factor cofilin (show CFL1 Proteins) by PP1 (show PPA1 Proteins) and PP2A (show PPP2R4 Proteins)

  9. down-regulation of FDH (show ADH5 Proteins) in tumors is proposed to be one of the cellular mechanisms that enhance proliferation.

  10. FDH (show ADH5 Proteins) antiproliferative effects on A549 cells include both G(1) cell cycle arrest and caspase (show CASP3 Proteins)-dependent apoptosis

Mouse (Murine) Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1) interaction partners

  1. Collectively, MNSFbeta (show FAU Proteins)/FDH (show ADH5 Proteins) complex formation may positively regulate apoptosis in thymocytes.

  2. Aldh1L1 is not a suitable marker for enteric glial cells.

  3. This study demonistrated that Aldh1L1 is expressed by postnatal neural stem cells in mice.

  4. These data provide the first evidence for localized differences in folate metabolism within the early neural tube and suggest that folate might modulate proliferation via effects on midline Aldh1l1(+) cells.

ALDH1L1 Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ALDH1L1

  • aldehyde dehydrogenase 1 family, member L1 (aldh1l1)
  • DKFZP469I2021 protein (DKFZP469I2021)
  • aldehyde dehydrogenase 1 family, member L1 (ALDH1L1)
  • aldehyde dehydrogenase 1 family, member L1 (Aldh1l1)
  • 10-fTHF protein
  • 10-FTHFDH protein
  • 1810048F20Rik protein
  • ALDH1L1 protein
  • DKFZp469C068 protein
  • FDH protein
  • Fthfd protein
  • Neut2 protein

Protein level used designations for ALDH1L1

10-FTHFDH , 10-formyltetrahydrofolate dehydrogenase , aldehyde dehydrogenase 1L1 , aldehyde dehydrogenase family 1 member L1 , cytosolic 10-formyltetrahydrofolate dehydrogenase , formyltetrahydrofolate dehydrogenase , aldehyde dehydrogenase 1 family, member L1 , 10-formyltetrahydrofolate dehydrogenase-like , FDH , FBP-CI

GENE ID SPECIES
496436 Xenopus (Silurana) tropicalis
100189626 Pongo abelii
460655 Pan troglodytes
100172380 Pongo abelii
100465263 Ailuropoda melanoleuca
100526683 Danio rerio
444321 Xenopus laevis
10840 Homo sapiens
505677 Bos taurus
107747 Mus musculus
64392 Rattus norvegicus
476506 Canis lupus familiaris
100622210 Sus scrofa
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