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The protein encoded by ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. Additionally we are shipping ALDH1L1 Kits (6) and ALDH1L1 Proteins (4) and many more products for this protein.
Showing 10 out of 133 products:
Mammalian Monoclonal ALDH1L1 Primary Antibody for ISt, IHC - ABIN1304519
Orr, Hsiao, Wang, Ho, Kim, Wang, Guo, Kang, Yu, Adame, Devidze, Dubal, Masliah, Conklin, Mucke: Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. in Nature neuroscience 2015
Show all 22 Pubmed References
Mammalian Monoclonal ALDH1L1 Primary Antibody for ISt, IHC - ABIN1304521
Barres: The mystery and magic of glia: a perspective on their roles in health and disease. in Neuron 2008
Show all 15 Pubmed References
Human Polyclonal ALDH1L1 Primary Antibody for IHC - ABIN965537
Chumanevich, Krupenko, Davies: The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain. in The Journal of biological chemistry 2004
Show all 6 Pubmed References
Human Polyclonal ALDH1L1 Primary Antibody for ELISA, WB - ABIN564710
Henkel, Roderfeld, Weiskirchen, Berres, Hillebrandt, Lammert, Meyer, Stühler, Graf, Roeb: Changes of the hepatic proteome in murine models for toxically induced fibrogenesis and sclerosing cholangitis. in Proteomics 2006
The crystal structures of apo (show C9orf3 Antibodies)-form N-terminal domain - FDH and its complexes with the substrate analogue 10-formyl-5,8-dideazafolate (10-FDDF) and with the products tetrahydrofolate and formate have been determined.
Knock-down of the fdh(10-Formyltetrahydrofolate dehydrogenase) gene impeded morphogenetic movement and caused incorrect cardiac positioning, defective hematopoiesis, notochord malformation and ultimate death of morphants
The polymorphic loci rs4646733, rs2305225, and rs2276731 in the ALDH1L1 gene maybe potential risk factors for neural tube defects in the Chinese population.
Data suggest that isoforms of FTHFD occur both in mitochondria and in cytosol; activity of cytosolic FTHFD appears to respond to supply of one-carbon groups in excess (show RCC1 Antibodies) of those required for classical one-carbon metabolism. [REVIEW]
JNK1 (show MAPK8 Antibodies)/2 phosphorylate Bid (show BID Antibodies) at Thr59 within the caspase (show CASP3 Antibodies) cleavage site in response to ALDH1L1.
ALDH1 (show ALDH1A1 Antibodies) is indicative of stemness and is a biomarker marker in colon cancer.
one variant in the ALDH1L1 locus, rs2364368, was associated with incident ischemic stroke.
The results in this study, for the first time, reveal that the mRNA and protein expressions of ALDH1L1 are significantly reduced in hepatocellular carcinoma tissues
Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
These studies support ALDH1L1 as a general CNS astroglial marker.
inhibition of cell motility by ALDH1L1 associated with dephosphorylation of the actin depolymerizing factor cofilin (show CFL1 Antibodies) by PP1 (show PPA1 Antibodies) and PP2A (show PPP2R4 Antibodies)
down-regulation of FDH (show ADH5 Antibodies) in tumors is proposed to be one of the cellular mechanisms that enhance proliferation.
Collectively, MNSFbeta (show FAU Antibodies)/FDH (show ADH5 Antibodies) complex formation may positively regulate apoptosis in thymocytes.
Aldh1L1 is not a suitable marker for enteric glial cells.
This study demonistrated that Aldh1L1 is expressed by postnatal neural stem cells in mice.
These data provide the first evidence for localized differences in folate metabolism within the early neural tube and suggest that folate might modulate proliferation via effects on midline Aldh1l1(+) cells.
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.
, 10-formyltetrahydrofolate dehydrogenase
, aldehyde dehydrogenase 1L1
, aldehyde dehydrogenase family 1 member L1
, cytosolic 10-formyltetrahydrofolate dehydrogenase
, formyltetrahydrofolate dehydrogenase
, aldehyde dehydrogenase 1 family, member L1
, 10-formyltetrahydrofolate dehydrogenase-like