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This protein belongs to the aldehyde dehydrogenase family of proteins. Additionally we are shipping Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (27) and Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins (16) and many more products for this protein.
Showing 10 out of 176 products:
Human Polyclonal ALDH2 Primary Antibody for FACS, IHC (p) - ABIN1881053
Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. in World journal of gastroenterology : WJG 2008
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Human Monoclonal ALDH2 Primary Antibody for ICC, FACS - ABIN1724796
Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. in European heart journal 2012
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Human Monoclonal ALDH2 Primary Antibody for ICC, FACS - ABIN1724795
Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. in Clinical toxicology (Philadelphia, Pa.) 2012
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Human Monoclonal ALDH2 Primary Antibody for ELISA, WB - ABIN513240
Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. in PLoS computational biology 2011
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Human Monoclonal ALDH2 Primary Antibody for FACS, IF - ABIN2452752
Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. in Journal of Alzheimer's disease : JAD 2014
Human Polyclonal ALDH2 Primary Antibody for ELISA, EIA - ABIN4279257
Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. in Alcoholism, clinical and experimental research 2009
ALDH-2 is involved in the remote ischemic preconditioning pathway.
This exome-wide association study indicated that C12orf51 rs11066280, MYL2 (show MYL2 Antibodies) rs12229654, and ALDH2 rs671 polymorphisms are linked to blood Pb levels in the Korean population.
Besides the amount and frequency of alcohol drinking, the combination of ALDH2 and ADH1B (show ADH1B Antibodies) polymorphisms predicts smoking initiation. This study suggests that alcohol tolerance regulated by ALDH2 and ADH1B (show ADH1B Antibodies) polymorphisms is associated with smoking initiation, and facilitates the development of targeted interventions to reduce smoking prevalence.
The ALDH2 Glu504Lys polymorphism was associated with endothelium-dependent dilation disorders in Chinese Han patients with essential hypertension, providing further evidence that this mutation and 'alcohol flush' are not harmless in this Asian population.
ALDH2 rs671 was significantly related with Type 2 Diabetic Mellitus. The ALDH2 rs671 might be able to be used as a predictor for the risk of Type 2 Diabetic Mellitus (Meta-Analysis)
ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.
We studied the ALDH2 genotypes of 35 Japanese FA patients and their mothers. We found that a normal maternal ALDH2 allele was not essential for fetal development of ALDH2-deficient patients, and none of the post-natal clinical parameters were clearly affected by the maternal ALDH2 genotype in these patients.
The study demonstrated that ALDH2*2/*2 may be an independent risk factor for ischemic stroke in Taiwanese men, but not in Taiwanese women.
The Glu504Lys polymorphism of the ALDH2 gene is associated with the carotid Intima-media thickness of Chinese Han patients with Essential Hypertension in Sichuan, China
ALDH2 polymorphisms may be susceptibility facts of alcoholic chronic pancreatitis, and it may be ethnic and race-dependent (Meta-Analysis)
Meta-analysis showed that a strong association exists between ALDH2 Glu487Lys polymorphism and the risk of esophageal cancer
ACADM (show ACADM Antibodies) and ALDH2 were predicted to be the target genes of miR (show MYLIP Antibodies)-224
analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (show ALDH1A1 Antibodies) and ALDH2
Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (show PRKCE Antibodies)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (show PPARG Antibodies) transcriptional activity.
In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.
Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress
prolonged treatment of apoE(-/-) mice with Alda-1 led to the beneficial changes in the expression of genes and proteins related to neuroplasticity and mitochondrial function.
ALDH2 activation is adequate to improve the autophagy flux by reducing the carbonyl modification on SIRT1 (show SIRT1 Antibodies), which in turn plays an important role in maintaining cardiac health during aging.
Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.
High concentrations of ETBE might result in reproductive toxicity in mice with normal active ALDH2, while low active/inactive ALDH2 significantly enhanced the ETBE-induced reproductive toxicity in mice.
ALDH2 deficiency enhances ethanol-induced disruption of intestinal epithelial tight junctions.
In mice lacking ALDH2, there would be increases in 4-hydroxynonenal and the appearance of Alzheimer's disease-like pathological changes.
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2 family (mitochondrial)
, aldehyde dehydrogenase 2 family (mitochondrial)a
, aldehyde dehydrogenase 2.1
, mitochondrial aldehyde dehydrogenase 2
, mitochondrial aldehyde dehydrogenase RF2B
, aldehyde dehydrogenase
, aldehyde dehydrogenase (NAD(+))
, ALDH class 2
, aldehyde dehydrogenase, mitochondrial
, aldehyde dehydrogenase, mitochondrial-like
, acetaldehyde dehydrogenase 2
, liver mitochondrial ALDH
, nucleus-encoded mitochondrial aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2, mitochondrial
, mitochondrial aldehyde dehydrogenase