anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antibodies

This protein belongs to the aldehyde dehydrogenase family of proteins. Additionally we are shipping Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (27) and Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALDH2 217 P05091
ALDH2 29539 P11884
ALDH2 11669 P47738
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Top anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Antibodies at antibodies-online.com

Showing 10 out of 172 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ALDH2 (arrow) using rabbit polyclonal ALDH2 Antibody (Center) (ABIN388202).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (Center) (ABIN388202), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of ALDH2 (arrow) using rabbit polyclonal ALDH2 Antibody (N-term) 56381 Da (ABIN388201). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (N-term) (ABIN388201), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ALDH2 monoclonal antibody  in HepG2 cell line lysates (35ug/lane). ALDH2 (arrow) was detected using the purified mab.(4ug/ml) ALDH2 Monoclonal Antibody  immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the ALDH2 Monoclonal Antibody for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- ALDH2 Picoband antibody, IHC(P) IHC(P): Human Kidney Cancer Tissue Anti- ALDH2 Picoband antibody, Western blotting All lanes: Anti ALDH2  at 0.5ug/ml Lane 1: Rat Kidney Tissue Lysate at 50ug Lane 2: Mouse Kidney Tissue Lysate at 50ug Predicted bind size: 56KD Observed bind size: 56KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit  Target Name: Aldh2  Sample Tissue: Mouse Small Intestine lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse Un-conjugated FACS, IF Anti-ALDH2 mouse monoclonal antibody (ABIN2452752) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ALDH2 (RC200505). Immunofluorescent staining of HepG2 cells using anti-ALDH2 mouse monoclonal antibody (ABIN2452752). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$245.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ALDH2 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Intestine Tissue Lysate Lane 3: Rat Lung Tissue Lysate Lane 4: Rat Kidney Tissue Lysate Anti-ALDH2 antibody, IHC(P) IHC(P): Human Liver Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details

ALDH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Antibodies

  1. Human Monoclonal ALDH2 Primary Antibody for FACS, IF - ABIN658993 : Yang, Yokoyama, Yokoyama, Huang, Wu, Shao, Niu, Wang, Liu, Zhou, Yang: Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis. in World journal of gastroenterology : WJG 2010 (PubMed)
    Show all 5 references for 658993

  2. Human Polyclonal ALDH2 Primary Antibody for FACS, IHC (p) - ABIN1881053 : Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. in World journal of gastroenterology : WJG 2008 (PubMed)
    Show all 3 references for 1881053

  3. Human Monoclonal ALDH2 Primary Antibody for ICC, FACS - ABIN1724796 : Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. in European heart journal 2012 (PubMed)
    Show all 2 references for 1724796

  4. Human Monoclonal ALDH2 Primary Antibody for FACS, IF - ABIN2452752 : Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. in Journal of Alzheimer's disease : JAD 2014 (PubMed)

More Antibodies against Aldehyde Dehydrogenase 2 Family (Mitochondrial) Interaction Partners

Rabbit Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH-2 is involved in the remote ischemic preconditioning pathway.

Human Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. The ALDH2 Glu504Lys polymorphism was associated with endothelium-dependent dilation disorders in Chinese Han patients with essential hypertension, providing further evidence that this mutation and 'alcohol flush' are not harmless in this Asian population.

  2. ALDH2 rs671 was significantly related with Type 2 Diabetic Mellitus. The ALDH2 rs671 might be able to be used as a predictor for the risk of Type 2 Diabetic Mellitus (Meta-Analysis)

  3. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  4. We studied the ALDH2 genotypes of 35 Japanese FA patients and their mothers. We found that a normal maternal ALDH2 allele was not essential for fetal development of ALDH2-deficient patients, and none of the post-natal clinical parameters were clearly affected by the maternal ALDH2 genotype in these patients.

  5. The study demonstrated that ALDH2*2/*2 may be an independent risk factor for ischemic stroke in Taiwanese men, but not in Taiwanese women.

  6. The Glu504Lys polymorphism of the ALDH2 gene is associated with the carotid Intima-media thickness of Chinese Han patients with Essential Hypertension in Sichuan, China

  7. ALDH2 polymorphisms may be susceptibility facts of alcoholic chronic pancreatitis, and it may be ethnic and race-dependent (Meta-Analysis)

  8. Meta-analysis showed that a strong association exists between ALDH2 Glu487Lys polymorphism and the risk of esophageal cancer

  9. ALDH2 could be a protective factor and negative predictor for severe intracranial vascular stenosis in ischemic stroke in Han Chinese.

  10. Study revealed that Glu504Lys of ALDH2 confers susceptibility to schizophrenia, possibly via modulation of the hippocampal-prefrontal functional connectivity

Cow (Bovine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  2. ACADM (show ACADM Antibodies) and ALDH2 were predicted to be the target genes of miR (show MYLIP Antibodies)-224

  3. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (show ALDH1A1 Antibodies) and ALDH2

Mouse (Murine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (show PRKCE Antibodies)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (show PPARG Antibodies) transcriptional activity.

  2. In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.

  3. Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress

  4. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  5. prolonged treatment of apoE(-/-) mice with Alda-1 led to the beneficial changes in the expression of genes and proteins related to neuroplasticity and mitochondrial function.

  6. ALDH2 activation is adequate to improve the autophagy flux by reducing the carbonyl modification on SIRT1 (show SIRT1 Antibodies), which in turn plays an important role in maintaining cardiac health during aging.

  7. Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.

  8. High concentrations of ETBE might result in reproductive toxicity in mice with normal active ALDH2, while low active/inactive ALDH2 significantly enhanced the ETBE-induced reproductive toxicity in mice.

  9. ALDH2 deficiency enhances ethanol-induced disruption of intestinal epithelial tight junctions.

  10. In mice lacking ALDH2, there would be increases in 4-hydroxynonenal and the appearance of Alzheimer's disease-like pathological changes.

Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antigen Profile

Protein Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

  • aldehyde dehydrogenase 2, tandem duplicate 1 (aldh2.1) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (aldh2) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) antibody
  • aldehyde dehydrogenase2 (aldh2) antibody
  • aldehyde dehydrogenase, mitochondrial-like (ALDH2) antibody
  • aldehyde dehydrogenase (aldH2) antibody
  • aldehyde dehydrogenase (NAD(+)) (aldH2) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (LOC100217978) antibody
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2) antibody
  • aldehyde dehydrogenase 2, mitochondrial (Aldh2) antibody
  • Ahd-5 antibody
  • Ahd5 antibody
  • ALDH-E2 antibody
  • aldh2 antibody
  • aldh2a antibody
  • ALDHI antibody
  • ALDM antibody
  • MGC80785 antibody
  • rf2b antibody
  • zgc:63786 antibody

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1

GENE ID SPECIES
393462 Danio rerio
446857 Xenopus laevis
448267 Xenopus (Silurana) tropicalis
452252 Pan troglodytes
542567 Zea mays
713451 Macaca mulatta
4226489 Rhodococcus jostii RHA1
5776113 Staphylococcus aureus subsp. aureus USA300_TCH1516
5952690 Halobacterium salinarum R1
9005267 Rhodobacter capsulatus SB 1003
100171596 Pongo abelii
100217978 Taeniopygia guttata
100338523 Oryctolagus cuniculus
100388478 Callithrix jacchus
217 Homo sapiens
29539 Rattus norvegicus
610941 Canis lupus familiaris
733685 Sus scrofa
508629 Bos taurus
416880 Gallus gallus
11669 Mus musculus
Selected quality suppliers for anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Antibodies
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