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This protein belongs to the aldehyde dehydrogenase family of proteins. Additionally we are shipping Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (29) and Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins (16) and many more products for this protein.
Showing 10 out of 177 products:
Human Polyclonal ALDH2 Primary Antibody for FACS, IHC (p) - ABIN1881053
Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. in World journal of gastroenterology : WJG 2008
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Human Monoclonal ALDH2 Primary Antibody for ICC, FACS - ABIN1724795
Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. in European heart journal 2012
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Human Monoclonal ALDH2 Primary Antibody for ICC, FACS - ABIN1724796
Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. in Clinical toxicology (Philadelphia, Pa.) 2012
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Human Monoclonal ALDH2 Primary Antibody for ELISA, WB - ABIN513240
Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. in PLoS computational biology 2011
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Human Polyclonal ALDH2 Primary Antibody for ELISA, EIA - ABIN4279257
Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. in Alcoholism, clinical and experimental research 2009
Human Monoclonal ALDH2 Primary Antibody for FACS, IF - ABIN2452752
Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. in Journal of Alzheimer's disease : JAD 2014
ALDH-2 is involved in the remote ischemic preconditioning pathway.
Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (show MAPK1 Antibodies), NF-kappaB (show NFKB1 Antibodies) and AP-1 (show FOSB Antibodies) signaling pathways.
ULK1 (show ULK1 Antibodies) played a crucial role in ALDH2-offered protective effect against high glucose exposure-induced cardiomyocyte injury through regulation of autophagy
ALDH2*2 is prevalent (51.0%) among Japanese STEMI patients, and those with ALDH2*2 had higher frequencies of coronary spasm and AFS and more-severe myocardial injury compared to those with ALDH2*1/*1.
ALDH2 polymorphism might be a promising prognostic factor for Japanese patients with p16 (show CDKN2A Antibodies)-negative OPC
In Japanese alcoholic men, the ALDH2*1/*1 genotype was associated with lower platelet counts for an 8-week hospital stay.
enhanced Alcohol elimination rate in ADH1B (show ADH1B Antibodies)*2 carriers and the increased salivary Acetaldehyde levels in ALDH2*1/*2 carriers among intoxicated alcoholics provide possible mechanisms explaining how each genetic polymorphism a ff ects the risk of alcoholism and upper aerodigestive tract cancer.
This review discusses the unexpected interrelationship between aldehydes, ALDH2 and hematopoietic stem cell biology, and in particular its relationship to Fanconi anemia (show PALB2 Antibodies).
All genotypes of ALDH2 showed no apparent difference in vasodilation in vivo nitroglycerin-mediated dilation.
ALDH2 polymorphism has several subtle effects on the lungs, some of which are similar to changes observed during normal aging, suggesting a "premature lung aging" effect.
Our findings elucidated the crucial role of multiple genetic variations in ADH1B (show ADH1B Antibodies) and ALDH2 as biomarkers of metachronous ESCC.
ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.
ACADM (show ACADM Antibodies) and ALDH2 were predicted to be the target genes of miR (show MYLIP Antibodies)-224
analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (show ALDH1A1 Antibodies) and ALDH2
Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (show MAPK1 Antibodies), NF-kappaB (show NFKB1 Antibodies) and AP-1 (show JUN Antibodies) signaling pathways.
ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.
Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (show PRKCE Antibodies)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (show PPARG Antibodies) transcriptional activity.
In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.
Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress
prolonged treatment of apoE(-/-) mice with Alda-1 led to the beneficial changes in the expression of genes and proteins related to neuroplasticity and mitochondrial function.
ALDH2 activation is adequate to improve the autophagy flux by reducing the carbonyl modification on SIRT1 (show SIRT1 Antibodies), which in turn plays an important role in maintaining cardiac health during aging.
Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.
High concentrations of ETBE might result in reproductive toxicity in mice with normal active ALDH2, while low active/inactive ALDH2 significantly enhanced the ETBE-induced reproductive toxicity in mice.
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2 family (mitochondrial)
, aldehyde dehydrogenase 2 family (mitochondrial)a
, aldehyde dehydrogenase 2.1
, mitochondrial aldehyde dehydrogenase 2
, mitochondrial aldehyde dehydrogenase RF2B
, aldehyde dehydrogenase
, aldehyde dehydrogenase (NAD(+))
, ALDH class 2
, aldehyde dehydrogenase, mitochondrial
, aldehyde dehydrogenase, mitochondrial-like
, acetaldehyde dehydrogenase 2
, liver mitochondrial ALDH
, nucleus-encoded mitochondrial aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2, mitochondrial
, mitochondrial aldehyde dehydrogenase