Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins (ALDH2)

This protein belongs to the aldehyde dehydrogenase family of proteins. Additionally we are shipping Aldehyde Dehydrogenase 2 Family (Mitochondrial) Antibodies (156) and Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALDH2 217 P05091
ALDH2 29539 P11884
ALDH2 11669 P47738
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Top Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$320.25
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 19 Days
$242.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Leishmania tarentolae His tag   1 mg Log in to see 60 to 71 Days
$3,384.33
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,415.50
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,417.33
Details
Yeast Horse His tag   1 mg Log in to see 60 to 71 Days
$3,417.33
Details

ALDH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus)

Mouse (Murine)

Top referenced Aldehyde Dehydrogenase 2 Family (Mitochondrial) Proteins

  1. Human ALDH2 Protein expressed in Escherichia coli (E. coli) - ABIN666745 : Crabb, Edenberg, Bosron, Li: Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant. in The Journal of clinical investigation 1989 (PubMed)
    Show all 2 references for 666745

More Proteins for Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Interaction Partners

Rabbit Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH-2 is involved in the remote ischemic preconditioning pathway.

Human Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. The ALDH2 Glu504Lys polymorphism was associated with endothelium-dependent dilation disorders in Chinese Han patients with essential hypertension, providing further evidence that this mutation and 'alcohol flush' are not harmless in this Asian population.

  2. ALDH2 rs671 was significantly related with Type 2 Diabetic Mellitus. The ALDH2 rs671 might be able to be used as a predictor for the risk of Type 2 Diabetic Mellitus (Meta-Analysis)

  3. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  4. We studied the ALDH2 genotypes of 35 Japanese FA patients and their mothers. We found that a normal maternal ALDH2 allele was not essential for fetal development of ALDH2-deficient patients, and none of the post-natal clinical parameters were clearly affected by the maternal ALDH2 genotype in these patients.

  5. The study demonstrated that ALDH2*2/*2 may be an independent risk factor for ischemic stroke in Taiwanese men, but not in Taiwanese women.

  6. The Glu504Lys polymorphism of the ALDH2 gene is associated with the carotid Intima-media thickness of Chinese Han patients with Essential Hypertension in Sichuan, China

  7. ALDH2 polymorphisms may be susceptibility facts of alcoholic chronic pancreatitis, and it may be ethnic and race-dependent (Meta-Analysis)

  8. Meta-analysis showed that a strong association exists between ALDH2 Glu487Lys polymorphism and the risk of esophageal cancer

  9. ALDH2 could be a protective factor and negative predictor for severe intracranial vascular stenosis in ischemic stroke in Han Chinese.

  10. Study revealed that Glu504Lys of ALDH2 confers susceptibility to schizophrenia, possibly via modulation of the hippocampal-prefrontal functional connectivity

Cow (Bovine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  2. ACADM (show ACADM Proteins) and ALDH2 were predicted to be the target genes of miR (show MYLIP Proteins)-224

  3. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (show ALDH1A1 Proteins) and ALDH2

Mouse (Murine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (show PRKCE Proteins)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (show PPARG Proteins) transcriptional activity.

  2. In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.

  3. Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress

  4. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  5. prolonged treatment of apoE(-/-) mice with Alda-1 led to the beneficial changes in the expression of genes and proteins related to neuroplasticity and mitochondrial function.

  6. ALDH2 activation is adequate to improve the autophagy flux by reducing the carbonyl modification on SIRT1 (show SIRT1 Proteins), which in turn plays an important role in maintaining cardiac health during aging.

  7. Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.

  8. High concentrations of ETBE might result in reproductive toxicity in mice with normal active ALDH2, while low active/inactive ALDH2 significantly enhanced the ETBE-induced reproductive toxicity in mice.

  9. ALDH2 deficiency enhances ethanol-induced disruption of intestinal epithelial tight junctions.

  10. In mice lacking ALDH2, there would be increases in 4-hydroxynonenal and the appearance of Alzheimer's disease-like pathological changes.

Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Protein Profile

Protein Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

  • aldehyde dehydrogenase 2, tandem duplicate 1 (aldh2.1)
  • aldehyde dehydrogenase 2 family (mitochondrial) (aldh2)
  • aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2)
  • aldehyde dehydrogenase2 (aldh2)
  • aldehyde dehydrogenase, mitochondrial-like (ALDH2)
  • aldehyde dehydrogenase (aldH2)
  • aldehyde dehydrogenase (NAD(+)) (aldH2)
  • aldehyde dehydrogenase 2 family (mitochondrial) (LOC100217978)
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2)
  • aldehyde dehydrogenase 2, mitochondrial (Aldh2)
  • Ahd-5 protein
  • Ahd5 protein
  • ALDH-E2 protein
  • aldh2 protein
  • aldh2a protein
  • ALDHI protein
  • ALDM protein
  • MGC80785 protein
  • rf2b protein
  • zgc:63786 protein

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1

GENE ID SPECIES
393462 Danio rerio
446857 Xenopus laevis
448267 Xenopus (Silurana) tropicalis
452252 Pan troglodytes
542567 Zea mays
713451 Macaca mulatta
4226489 Rhodococcus jostii RHA1
5776113 Staphylococcus aureus subsp. aureus USA300_TCH1516
5952690 Halobacterium salinarum R1
9005267 Rhodobacter capsulatus SB 1003
100171596 Pongo abelii
100217978 Taeniopygia guttata
100338523 Oryctolagus cuniculus
100388478 Callithrix jacchus
217 Homo sapiens
29539 Rattus norvegicus
610941 Canis lupus familiaris
733685 Sus scrofa
508629 Bos taurus
416880 Gallus gallus
11669 Mus musculus
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