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Aldehyde Dehydrogenase 3 Family, Member A1 Proteins (ALDH3A1)

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. Additionally we are shipping ALDH3A1 Antibodies (98) and ALDH3A1 Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALDH3A1 218 P30838
ALDH3A1 25375 P11883
ALDH3A1 11670 P47739
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Top ALDH3A1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$414.75
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,607.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,268.83
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$3,268.83
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$154.00
Details

ALDH3A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced ALDH3A1 Proteins

  1. Human ALDH3A1 Protein expressed in Escherichia coli (E. coli) - ABIN667760 : Bogucka, Giebułtowicz, Zawada, Wroczyński, Wierzchowski, Pietrzak, Piekarczyk, Romanowska: The oxidation status of ALDH3A1 in human saliva and its correlation with antioxidant capacity measured by ORAC method. in Acta poloniae pharmaceutica 2009 (PubMed)
    Show all 2 references for ABIN667760

  2. Human ALDH3A1 Protein expressed in Baculovirus infected Insect Cells - ABIN2005254 : Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: Lysine acetylation targets protein complexes and co-regulates major cellular functions. in Science (New York, N.Y.) 2009 (PubMed)

More Proteins for Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1) Interaction Partners

Human Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1) interaction partners

  1. Down-regulation of ALDH3 activity in trophoblast stem cells initiates trophoblast differentiation during placental development.

  2. ALDH3A1 has a role in the maintenance of corneal epithelial homeostasis by simultaneously modulating proliferation and differentiation through both enzymatic and non-enzymatic mechanisms

  3. Reported increased expression of ALDH3A1, PDIA3 (show PDIA3 Proteins), and PRDX2 (show PRDX2 Proteins) in pterygia using a proteomic approach. These proteins are presumed to have a protective role against oxidative stress-induced (show SQSTM1 Proteins) apoptosis.

  4. SiRNA-mediated suppression of ALDH3A1 blocked ALDH enzymatic activity and augmented cytotoxicity in CSE-exposed cells.

  5. While ALDH3A1 was not found in prostate glands, it was present in prostatic intraepithelial neoplasia, further increased in carcinomas, and upregulated in lymphatic metastases. ALDH3A1 increased in DU145-cell-derived lung metastasis vs. local xenografts.

  6. No correlation between ALDH3A1 expression and patient survival or tumour recurrence was observed.In conclusion, ALDH3A1 is a marker of activation of the Wnt/ss-catenin pathway in hepatocellular carcinoma

  7. ALDH3A1 provides exceptional protection from the adverse effects of pathophysiological concentrations of 4-HNE (show ELANE Proteins) such as may occur during periods of oxidative stress

  8. through modulation of PPARgamma (show PPARG Proteins) or ALDH3A1, it may be possible to reduce cell proliferation in tumor cells or stimulate cell proliferation in normal cells during tissue regeneration.

  9. the UV-induced inactivation of ALDH3A1 is a result of non-native aggregation and associated structural changes rather than specific damage to the active site Cys (show DNAJC5 Proteins)

  10. Antihypertensives, nonopioid analgesics and hormonal contraceptives significantly affect the salivary ALDH3A1 activity.

Mouse (Murine) Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1) interaction partners

  1. ALDH3A1 has a role in the maintenance of corneal epithelial homeostasis by simultaneously modulating proliferation and differentiation through both enzymatic and non-enzymatic mechanisms

  2. ADH3 protects liver from steatosis by supporting normal lipid metabolism and prevents progression of steatosis into steatohepatitis by maintaining the cellular glutathione level.

  3. focused on ALDH3A1, which is enriched in the upper aerodigestive track, and identified Alda-89 as a small molecule that enables ALDH3A1 to metabolize acetaldehyde

  4. Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status.

  5. ALDH activity is critical to metabolize acetaldehyde and prevent its accumulation to toxic levels that disrupt not only granulosa cell and theca cell functions but also proper oocyte development

  6. ALDH3A1 can compensate for ALDH1A1 (show ALDH1A1 Proteins) in bone marrow & is important in B-cell development. Mice deficient in ALDH3A1 have a block in B-cell development as well as abnormalities in cell cycling, intracellular signaling, and gene expression.

  7. corneal ALDH3A1 and lens ALDH1A1 (show ALDH1A1 Proteins) protect the eye against cataract formation via nonenzymatic (light filtering) and enzymatic (detoxification) functions.

  8. The alleles ADH3*1 and genotype ADH3*1/ADH3*1 were significantly more frequent in men than in women, while alleles ADH3*2 and genotype ADH3*2/ADH3*2 were more common in women.

  9. Pax6 (show PAX6 Proteins), Oct1 (show POU2F1 Proteins), and p300 (show NOTCH1 Proteins) activate gene expression of the corneal crystallin Aldh3a1 in the mouse.

ALDH3A1 Protein Profile

Protein Summary

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with ALDH3A1

  • aldehyde dehydrogenase 3 family, member A1 (ALDH3A1)
  • aldehyde dehydrogenase (aldH3)
  • aldehyde dehydrogenase, dimeric NADP-preferring (CLL_A1665)
  • aldehyde dehydrogenase, dimeric NADP-preferring (LOC100281700)
  • aldehyde dehydrogenase, dimeric NADP-preferring (LOC100285809)
  • aldehyde dehydrogenase 3 family, member A1 (Aldh3a1)
  • aldehyde dehydrogenase family 3, subfamily A1 (Aldh3a1)
  • Ahd-4 protein
  • Ahd-c protein
  • Ahd4 protein
  • AHDC protein
  • Aldh protein
  • Aldh3 protein
  • ALDHIII protein

Protein level used designations for ALDH3A1

aldehyde dehydrogenase 3 family, memberA1 , aldehyde dehydrogenase 3 family, member A1 , aldehyde dehydrogenase , aldehyde dehydrogenase, dimeric NADP-preferring , aldehyde dehydrogenase, dimeric NADP-preferring-like , aldehyde dehydrogenase isozyme 3 , aldehyde dehydrogenase type III , stomach aldehyde dehydrogenase , Aldehyde dehydrogenase (Ahd-c) , HTC-ALDH , aldehyde dehydrogenase 3A1 , aldehyde dehydrogenase class 3 , aldehyde dehydrogenase family 3 member A1 , aldehyde dehydrogenase family 3 subfamily A1 , aldehyde dehydrogenase family 3, member A1 , tumor-associated aldehyde dehydrogenase tumor ALDH , BCP54 , corneal 15.8 kDa protein , corneal protein 54, transparentin , dehydrogenase 3, dimeric NAPD-prefering , transparentin , ALDH3 , ALDHIII , alcohol dehydrogenase family 3, subfamily A1 , aldehyde dehydrogenase 3, stomach cytosolic (class 3) , aldehyde dehydrogenase 4 , dioxin-inducible aldehyde dehydrogenase 3

GENE ID SPECIES
468186 Pan troglodytes
703870 Macaca mulatta
100020131 Monodelphis domestica
100077088 Ornithorhynchus anatinus
5952753 Halobacterium salinarum R1
6293568 Clostridium botulinum B str. Eklund 17B
100281700 Zea mays
100285809 Zea mays
100385438 Callithrix jacchus
218 Homo sapiens
25375 Rattus norvegicus
281617 Bos taurus
489526 Canis lupus familiaris
101108502 Ovis aries
11670 Mus musculus
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