You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) Antibodies

AKR1B1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. Additionally we are shipping Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Kits (33) and Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AKR1B1 58810 Q9JII6
AKR1B1 78959 P51635
AKR1B1 231 P15121
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-AKR1B1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-AKR1B1 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AKR1B1 antibody (C-term) (ABIN389205), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-AKR1B1 Pab (ABIN389205) in A375 cell line lysates (35 µg/lane).AKR1B1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of anti-AKR1B1 Pab (ABIN389206) in Jurkat cell line lysates (35 µg/lane).AKR1B1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with AKR1B1 antibody (Center) (ABIN389206), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, using AKR1B1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

AKR1B1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
, ,
,
, , , , , , , , , , ,
Rat (Rattus) ,
,

, , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , ,

Top referenced anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Antibodies

  1. Human Polyclonal AKR1B1 Primary Antibody for EIA, IF - ABIN357880 : Steuber, Heine, Podjarny, Klebe: Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. in Journal of molecular biology 2008 (PubMed)
    Show all 3 references for ABIN357880

  2. Human Polyclonal AKR1B1 Primary Antibody for IF, IHC (p) - ABIN389205 : Gleissner, Sanders, Nadler, Ley: Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis. in Arteriosclerosis, thrombosis, and vascular biology 2008 (PubMed)
    Show all 3 references for ABIN389205

  3. Human Polyclonal AKR1B1 Primary Antibody for EIA, IHC (p) - ABIN357881 : Grundmann, Bohn, Obermeier, Amann: Cloning and prokaryotic expression of a biologically active human placental aldose reductase. in DNA and cell biology 1990 (PubMed)
    Show all 3 references for ABIN357881

  4. Human Polyclonal AKR1B1 Primary Antibody for IHC, ELISA - ABIN184795 : Fujii, Hamaoka, Matsumoto, Fujii, Yamaguchi, Egashira, Miyoshi, Niikawa, Taniguchi: The structural organization of the human aldehyde reductase gene, AKR1A1, and mapping to chromosome 1p33-->p32. in Cytogenetics and cell genetics 1999 (PubMed)

More Antibodies against Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Interaction Partners

Pig (Porcine) Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) interaction partners

  1. Structure of ALR1 in ternary complex with NADPH (show NQO1 Antibodies) and 3,5-dichlorosalicylic acid is reported as well as the implications for inhibitor binding and selectivity.

Cow (Bovine) Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) interaction partners

  1. L-idose is the best alternative to D-glucose in studies on aldose reductase.

  2. prostaglandin F synthase (show AKR1C3 Antibodies) activity of human and bovine aldo-keto reductases

Mouse (Murine) Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) interaction partners

  1. Aldose reductase acts as a switch which can regulate microglia by polarizing cells after spinal cord injury.

  2. Aldose reductase contributes to diabetes-mediated mitochondrial dysfunction and damage through the activation of p53 (show TP53 Antibodies).

  3. Data indicate that inhibition of AR alleviates the MCD (show MLYCD Antibodies) diet-induced liver inflammation and fibrosis in db/db (show LEPR Antibodies) mice, probably through dampening CYP2E1 (show CYP2E1 Antibodies) mediated-oxidative stress and ameliorating the expression of pro-inflammatory cytokines.

  4. FMHM suppressed the activity of AR-dependent phospholipase C (show PLC Antibodies)/protein (show HNRNPC Antibodies) kinase C (show PKC Antibodies) signaling, which further resulted in downstream inactivation of the IkappaB kinase (show CHUK Antibodies)/IkappaB/nuclear factor-kappa B inflammatory pathway.

  5. Allergen-induced airway remodeling is mediated by AR and its inhibition blocks the progression of remodeling via inhibiting TGFbeta1 (show TGFB1 Antibodies)-induced Smad (show SMAD1 Antibodies)-independent and PI3K/AKT (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies)-dependent pathway.

  6. BGG-mediated inhibition of aldose reductase prevented LPS (show TLR4 Antibodies)-induced activation of JNK (show MAPK8 Antibodies).

  7. The crystal structure of AKR1a4 in its apo (show C9orf3 Antibodies) form at high resolution.

  8. crystal of AKR1B3 was tetragonal, belonging to space group P4(1)2(1)2 or P4(3)2(1)2, with unit-cell parameters a = b = 107.62, c = 120.76 A

  9. the role of AKR1B3 in regulating advanced glycosylation end products and advanced lipoxidation end products

  10. a Y48F/H110F double mutant of AKR1B3 completely lost PGDS (show PTGDS Antibodies) activity and showed only 2.9% of PGFS (show AKR1C3 Antibodies) activity

Human Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) interaction partners

  1. ALR (show GFER Antibodies) C(-106)T polymorphism was not associated with an increased risk of Diabetic Retinopathy; subgroup analysis showed a genetic association between ALR (show GFER Antibodies) C(-106)T polymorphism and the risk of Diabetic Retinopathy of type 1 Diabetes but not Diabetic Retinopathy of type 2 Diabetes(Meta-Analysis)

  2. Higher expression of PLA2G2A (show PLA2G2A Antibodies), PTGS2 (show PTGS2 Antibodies), AKR1B1, AKR1C3 (show AKR1C3 Antibodies) and ABCC4 (show ABCC4 Antibodies) was seen in 22-B endometriosis cells.

  3. Data conclude that AKR1B1 and TM6SF1 may serve as candidate methylation biomarkers for early breast cancer detection.

  4. L-idose is the best alternative to D-glucose in studies on aldose reductase.

  5. role of the human aldose reductase AKR1B1 in prostaglandin (PG) F2 alpha synthesis in human subcutaneous and omental adipose tissue

  6. One of the most striking changes involved sorbitol dehydrogenase (show SORD Antibodies), a key enzyme in the polyol pathway. Validation studies revealed dramatically increased sorbitol dehydrogenase (show SORD Antibodies) concentrations and activity in adenomas and cancer cell lines, along with important changes in the expression of other enzymes in the same (AKR1B1) and related (KHK (show KHK Antibodies)) pathways.

  7. In type 2 diabetic patients with suboptimal glycaemic control, the z-4 allele of ALR2 (CA)n polymorphism was independently associated with increased susceptibility to cataracts.

  8. prostaglandin F synthase (show AKR1C3 Antibodies) activity of human and bovine aldo-keto reductases

  9. Aldose reductase contributes to diabetes-mediated mitochondrial dysfunction and damage through the activation of p53 (show TP53 Antibodies).

  10. Aldose reductase gene may not be significantly associated with diabetic retinopathy in Chinese patients with type 2 diabetes mellitus.

Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) Antigen Profile

Protein Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Gene names and symbols associated with AKR1B1

  • aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1) antibody
  • aldo-keto reductase family 1, member B1 (aldose reductase) (akr1b1) antibody
  • aldo-keto reductase family 1, member B1-like (aldose reductase) (AKR1B1L) antibody
  • aldo-keto reductase family 1, member A1 (aldehyde reductase) (AKR1A1) antibody
  • aldo-keto reductase family 1, member A1 (aldehyde reductase) (Akr1a1) antibody
  • aldo-keto reductase family 1, member B1 (aldose reductase) (Akr1b1) antibody
  • aldo-keto reductase family 1, member B3 (aldose reductase) (Akr1b3) antibody
  • 2610201A18Rik antibody
  • ADR antibody
  • Ahr-1 antibody
  • Ahr1 antibody
  • Akr1a4 antibody
  • Akr1b1 antibody
  • Akr1b3 antibody
  • Akr1b4 antibody
  • akr1b7 antibody
  • Aldor1 antibody
  • Aldr1 antibody
  • ALDRED antibody
  • Alr antibody
  • ALR-P-I antibody
  • ALR1 antibody
  • ALR2 antibody
  • AR antibody
  • RATALDRED antibody
  • zgc:86611 antibody

Protein level used designations for AKR1B1

aldo-keto reductase family 1, member B1-like , aldose reductase , aldo-keto reductase family 1, member B1 (aldose reductase) , alcohol dehydrogenase , alcohol dehydrogenase [NADP(+)] , aldehyde reductase , aldo-keto reductase family 1 member A1 , aldo-keto reductase family 1, member A4 (aldehyde reductase) , 3-DG-reducing enzyme , Lii5-2 CTCL tumor antigen , aldehyde reductase 1 , aldo-keto reductase family 1 member B1 , low Km aldose reductase , 20-alpha-HSD , 20-alpha-hydroxysteroid dehydrogenase , AR , Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene) , aldo-keto reductase family 1, member B4 (aldose reductase)

GENE ID SPECIES
737737 Pan troglodytes
398904 Xenopus laevis
418171 Gallus gallus
705957 Macaca mulatta
100585224 Nomascus leucogenys
396924 Sus scrofa
618607 Bos taurus
58810 Mus musculus
78959 Rattus norvegicus
231 Homo sapiens
415138 Danio rerio
607537 Canis lupus familiaris
396816 Sus scrofa
317748 Bos taurus
100009122 Oryctolagus cuniculus
24192 Rattus norvegicus
100718017 Cavia porcellus
101120824 Ovis aries
11677 Mus musculus
Selected quality suppliers for anti-Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) Antibodies
Did you look for something else?