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AlkB, Alkylation Repair Homolog 5 (E. Coli) Proteins (ALKBH5)

Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).. Additionally we are shipping ALKBH5 Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ALKBH5 ALKBH5 303193  
ALKBH5 54890 Q6P6C2
ALKBH5 268420 Q3TSG4
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Top ALKBH5 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,982.83
Details

ALKBH5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for AlkB, Alkylation Repair Homolog 5 (E. Coli) (ALKBH5) Interaction Partners

Human AlkB, Alkylation Repair Homolog 5 (E. Coli) (ALKBH5) interaction partners

  1. The ALKBH5 gene may play a role in conferring risk of MDD in the Chinese population.

  2. Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.

  3. Modelling substrate into the active site of ALKBH5 reveals conserved residues important for recognition and demethylation mechanisms.

  4. findings provide a structural basis for understanding the substrate recognition specificity of Alkbh5 and offer a foundation for selective drug design against AlkB (show ALKBH Proteins) members

  5. ALKBH5 is a RNA demethylase and its action strongly suggests that the reversible methyladenosine modification has fundamental and broad functions in mammalian cells.

  6. ALKBH5 may have a role in the regulation of cellular responses to hypoxia as a class of HIF-transcriptional target gene

ALKBH5 Protein Profile

Protein Summary

Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).

Gene names and symbols associated with ALKBH5

  • alkB, alkylation repair homolog 5 (E. coli) (Alkbh5)
  • alkB, alkylation repair homolog 5 (alkbh5)
  • alkB, alkylation repair homolog 5 (E. coli) (ALKBH5)
  • Abh5 protein
  • AW050020 protein
  • AW215868 protein
  • E130207K11 protein
  • Ofoxd protein
  • OFOXD1 protein
  • RGD1309496 protein

Protein level used designations for ALKBH5

RNA demethylase ALKBH5 , alkylated DNA repair protein alkB homolog 5 , alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 , probable alpha-ketoglutarate-dependent dioxygenase ABH5 , oxoglutarate and iron-dependent oxygenase domain containing

GENE ID SPECIES
303193 Rattus norvegicus
444130 Xenopus laevis
54890 Homo sapiens
268420 Mus musculus
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