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Alkaline Ceramidase 2 Proteins (ACER2)

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. Additionally we are shipping ACER2 Antibodies (11) and ACER2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACER2 340485 Q5QJU3
ACER2 230379 Q8VD53
Rat ACER2 ACER2 313339  
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Top ACER2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

ACER2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Alkaline Ceramidase 2 (ACER2) Interaction Partners

Human Alkaline Ceramidase 2 (ACER2) interaction partners

  1. c-Src (show SRC Proteins)-mediated signal positively regulates ACER activity in a Ca2 (show CA2 Proteins)+-independent manner.

  2. Results suggest that up-regulation of the ACER2/DHS pathway mediates the cytotoxicity of 4-HPR in tumor cells and that up-regulating or activating ACER2 may improve the anti-cancer activity of 4-HRR and other DHC-inducing agents.

  3. ACER2 has broad substrate specificity and requires Ca(2 (show CA2 Proteins)+) for its activity; ACER2 has the cytosolic C terminus and luminal N terminus, which are essential for its activity, correct cellular localization, and regulation for protein glycosylation

  4. ACER2/sphingosine pathway plays an important role in regulating beta1 maturation and cell adhesion mediated by beta1 integrins

ACER2 Protein Profile

Protein Summary

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006

Gene names and symbols associated with Alkaline Ceramidase 2 Proteins (ACER2)

  • alkaline ceramidase 2 (ACER2)
  • alkaline ceramidase 2 (acer2)
  • alkaline ceramidase 2 (LOC100337862)
  • alkaline ceramidase 2 (Acer2)
  • 2410116I05Rik protein
  • ALKCDase2 protein
  • Asah3l protein
  • CRG-L1 protein
  • maCER2 protein

Protein level used designations for Alkaline Ceramidase 2 Proteins (ACER2)

alkaline ceramidase 2 , N-acylsphingosine amidohydrolase 3-like , putative protein, with at least 4 transmembrane domains, of eukaryotic origin (5H174) , alkCDase 2 , alkaline CDase 2 , ceramide hydrolase , haCER2 , cancer related gene-liver 1 (CRG-L1) , cancer-related gene liver 1 protein

GENE ID SPECIES
481553 Canis lupus familiaris
779231 Xenopus laevis
100337862 Oryctolagus cuniculus
465015 Pan troglodytes
540732 Bos taurus
549870 Xenopus (Silurana) tropicalis
100528685 Ictalurus punctatus
340485 Homo sapiens
230379 Mus musculus
313339 Rattus norvegicus
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