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Alkaline Phosphatase, Liver/bone/kidney (ALPL) ELISA Kits

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). Additionally we are shipping ALPL Antibodies (162) and ALPL Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ALPL 249 P05186
ALPL 11647 P09242
ALPL 25586 P08289
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Top ALPL ELISA Kits at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$720.00
Details
Rat 0.28 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
$760.00
Details
Human 37 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Mouse 0.1 U/L   96 Tests Log in to see 11 to 13 Days
$785.71
Details
Rabbit
  96 Tests Log in to see 11 to 13 Days
$785.71
Details
Pig
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Guinea Pig
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Monkey
  96 Tests Log in to see 11 to 13 Days
$817.14
Details
Sheep
  96 Tests Log in to see 11 to 13 Days
$817.14
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Chicken
  96 Tests Log in to see 11 to 13 Days
$817.14
Details

Top referenced ALPL ELISA Kits

  1. Mouse (Murine) ALPL ELISA Kit for Sandwich ELISA - ABIN415660 : Wu, Lin, Liou, Lu, Chen, Fu, Yang: Dextromethorphan inhibits osteoclast differentiation by suppressing RANKL-induced nuclear factor-?B activation. in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2013 (PubMed)
    Show all 3 references for ABIN415660

  2. Rat (Rattus) ALPL ELISA Kit for Sandwich ELISA - ABIN416228 : Gradosova, Zivna, Svejkovska, Palicka, Tichy, Zivny: The role of atorvastatin in bone metabolism in male albino Wistar rats. in Die Pharmazie 2011 (PubMed)
    Show all 4 references for ABIN416228

More ELISA Kits for ALPL Interaction Partners

Human Alkaline Phosphatase, Liver/bone/kidney (ALPL) interaction partners

  1. Analysis of a series of multiple N-glycan depletion mutants in TNSALP revealed that three N-glycans on N230, N271 and N303 were the minimal requirement for the structure and function of TNSALP and a prerequisite for its stable expression in a cell.

  2. The presence of TNAP increased the dynamics and decreased the ordering of model membranes.

  3. These data confirm that TNAP is co-expressed by dental pulp stromal cells together with other bone marrow stromal cells markers and show that cell density affects TNAP expression levels.

  4. ALP (show ALP ELISA Kits) quartiles were significantly associated with albuminuria in participants with estimated glomerular filtration rate>120 90-119, 60-89 and <60 mL/min/1.73 Higher ALP (show ALP ELISA Kits) levels are significantly associated with renal hyperfiltration

  5. during skeletal mineralization, the building Ca2 (show CA2 ELISA Kits)+ gradient first activates TNAP, but gradually inactivates it at high Ca2 (show CA2 ELISA Kits)+ concentrations, toward completion of mineralization.

  6. these data demonstrate that TNAP activity is significantly increased in the brain in both the sporadic and familial forms of Alzheimer's Disease (AD) and that TNAP activity is significantly increased in the plasma in AD patients

  7. A non-linear relationship exists between serum levels of ALP (show ALP ELISA Kits) and phosphate and risk of total mortality from cardiovascular diseases.

  8. ALP (show ALP ELISA Kits) mRNA binds to and is stabilized by vimentin (show VIM ELISA Kits).

  9. Elevated AP was associated with the presence of COPD (show ARCN1 ELISA Kits) and respiratory symptoms (cough, wheezing).

  10. A novel role of alkaline phosphatase in the ERK1 and ERK2 dephosphorylation in renal cell carcinoma cell lines

Mouse (Murine) Alkaline Phosphatase, Liver/bone/kidney (ALPL) interaction partners

  1. TNAP in the vasculature contributes to the pathology of medial vascular calcification and that it is a druggable target.

  2. In cardiac fibroblasts, TNAP expression and activity is induced by sFRP2 (show SFRP2 ELISA Kits).

  3. p107 (show RBL1 ELISA Kits) is required for the efficient recruitment of an activating SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) chromatin-remodeling complex, an essential event in Alpl induction.

  4. Inhibition of rhBMP-2-induced ALP activity by intracellular delivery of SMURF1 (show SMURF1 ELISA Kits) in murine calvarial preosteoblast cells.

  5. Findings demonstrate that Alpl(-/-) mice exhibit a craniofacial skeletal phenotype similar to that seen in infants with HPP (show HPR ELISA Kits), including true bony craniosynostosis in the context of severely diminished bone mineralization

  6. CD73 and TNAP play interactive roles to metabolize luminally applied 5'-AMP (show TMPRSS5 ELISA Kits) in the renal vasculature such that inhibition of both is required to inhibit the production of adenosine.

  7. TNAP plays a role in governing the phosphorylation status of phospholamban (show PLN ELISA Kits) in the sarcoplasmic reticulum.

  8. Taken together, these data indicate that ATF3 (show ATF3 ELISA Kits) is a novel negative regulator of osteoblast differentiation by specifically suppressing ALP gene expression in preosteoblasts.

  9. data suggest that the promineralization role of TNAP may be related not only to its accepted pyrophosphatase activity but also to its ability to modify the phosphorylation status of OPN (show SPP1 ELISA Kits).

  10. mineralization abnormalities of dentin; reduced overall mineralization with decreased matrix vesicle mineralization in the Phospho1(-/-) mice; almost complete absence of matrix vesicles in mice; further reduction in mineralization.

Cow (Bovine) Alkaline Phosphatase, Liver/bone/kidney (ALPL) interaction partners

  1. The peri (show PLIN1 ELISA Kits)-partum characteristics of serum bone-specific alkaline phosphatase (BAP (show PHB2 ELISA Kits)) and urinary deoxypyridinoline (DPD (show DPYD ELISA Kits)) in dairy cattle are reported.

  2. GPI (show GPI ELISA Kits)-anchored proteins are localized on the outer layer of plasma membranes and clustered in microdomains generally called lipid rafts.

ALPL Antigen Profile

Antigen Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with ALPL

  • alkaline phosphatase, liver/bone/kidney (alpl) antibody
  • alkaline phosphatase, liver/bone/kidney (ALPL) antibody
  • alkaline phosphatase, intestinal, gene 2 (alpi.2) antibody
  • alkaline phosphatase, liver/bone/kidney (Alpl) antibody
  • Akp-2 antibody
  • Akp2 antibody
  • ALP antibody
  • alpl antibody
  • AP-TNAP antibody
  • APTNAP antibody
  • HOPS antibody
  • iap antibody
  • PHOA antibody
  • TNAP antibody
  • TNS-AP antibody
  • TNSALP antibody

Protein level used designations for ALPL

tissue-nonspecific alkaline phosphatase , alkaline phosphatase, tissue-nonspecific isozyme , tissue non-specific alkaline phosphatase , alkaline phosphatase, liver/bone/kidney , alkaline phosphatase, tissue-nonspecific isozyme-like , alkaline phosphatase liver/bone/kidney isozyme , alkaline phosphomonoesterase , glycerophosphatase , liver/bone/kidney-type alkaline phosphatase , tissue-nonspecific ALP , alkaline phosphatase 2, liver , AP-TNAP , TNSALP , Tissue-nonspecific ALP alkaline phosphatase , alkaline phosphatase tissue non-specific isoform , liver/bone/kidney isozyme

GENE ID SPECIES
380589 Xenopus laevis
403548 Canis lupus familiaris
717809 Macaca mulatta
100144722 Xenopus (Silurana) tropicalis
100401643 Callithrix jacchus
100440770 Pongo abelii
100031702 Monodelphis domestica
456600 Pan troglodytes
100602436 Nomascus leucogenys
249 Homo sapiens
11647 Mus musculus
25586 Rattus norvegicus
280994 Bos taurus
100170147 Sus scrofa
727689 Felis catus
396317 Gallus gallus
101123195 Ovis aries
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