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Alpha2-Plasmin Inhititor Proteins (alpha2-PI)

alpha2-PI encodes a member of the serpin family of serine protease inhibitors. Additionally we are shipping Alpha2-Plasmin Inhititor Antibodies (94) and Alpha2-Plasmin Inhititor Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
alpha2-PI 18816 Q61247
alpha2-PI 5345 P08697
alpha2-PI 282522 P28800
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Top Alpha2-Plasmin Inhititor Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Human Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$120.75
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details

alpha2-PI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
,
Human , , ,
,
Cow (Bovine)

Top referenced Alpha2-Plasmin Inhititor Proteins

  1. Human alpha2-PI Protein expressed in Human Cells - ABIN2002531 : Potempa, Shieh, Travis: Alpha-2-antiplasmin: a serpin with two separate but overlapping reactive sites. in Science (New York, N.Y.) 1988 (PubMed)
    Show all 4 references for ABIN2002531

  2. Mouse (Murine) alpha2-PI Protein expressed in Human Cells - ABIN2007443 : Christiansen, Jackson, Lee, McKee: The effect of a single nucleotide polymorphism on human alpha 2-antiplasmin activity. in Blood 2007 (PubMed)
    Show all 4 references for ABIN2007443

More Proteins for Alpha2-Plasmin Inhititor (alpha2-PI) Interaction Partners

Mouse (Murine) Alpha2-Plasmin Inhititor (alpha2-PI) interaction partners

  1. alpha2AP has a profibrotic effect probably not by the action as a plasmin (show PLG Proteins) inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis

  2. Alpha 2 antiplasmin is involved in the recruitment of lymphocytes in the peripheral tissues.Alpha 2 antiplasmin contributes to the maintenance of immunological functions that are related to IgE.

  3. Plasmin (show PLG Proteins)/alpha(2)-AP system played an important role in hepatic repair via clearance from the injury area.

  4. PgtE mediated degradation of the antiprotease alpha(2)-antiplasmin leads to functional inactivation of the antiprotease in infected macrophages

  5. alpha2-antiplasmin induction inhibits E-cadherin (show CDH1 Proteins) processing mediated by the plasminogen (show PLG Proteins) activator/plasmin (show PLG Proteins) system, leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion

  6. The lack of alpha2AP attenuated TGF-beta(1 (show TGFB1 Proteins)) synthesis, thereby resulting in attenuated fibrosis

  7. 2.65A X-ray crystal structure of an N-terminal truncated murine alpha(2)-antiplasmin.

  8. Results show that alpha2-antiplasmin is a critical regulator for vascular remodeling by inhibiting p53 (show TP53 Proteins)/p21 pathway.

Human Alpha2-Plasmin Inhititor (alpha2-PI) interaction partners

  1. alpha2AP has a profibrotic effect probably not by the action as a plasmin (show PLG Proteins) inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis

  2. Possession of the alpha2AP 407Lys allele was negatively associated with AAA (show APP Proteins), and thus changes in alpha2AP may affect aneurysm growth and development.

  3. Two differentially expressed proteins, alpha-1-antitrypsin (SERPINA1) and alpha-2 antiplasmin (SERPINF2) are associated with purpura fulminans.

  4. Data suggest serum A2AP (SERPINF2) level can serve as biomarker for diabetic retinopathy; levels of A2AP (but not fibrinogen, plasminogen (show PLG Proteins), or plasminogen activator inhibitor 1 (show SERPINE1 Proteins)) are up-regulated in hyperglycemic type 1 diabetes with retinopathy.

  5. Study revealed that plasmin (show PLG Proteins) was present in tumor tissue, and that it was responsible for processing progalanin to galanin (show GAL Proteins)(1-20) in the extracellular environment.

  6. Data suggest that decreased amounts of alpha2-plasmin (show PLG Proteins) inhibitor in plasma vs serum ex vivo may reflect reduced factor XIII (show UGDH Proteins) (FXIII) in vivo; thus, plasma vs serum alpha2-plasmin (show PLG Proteins) inhibitor may be useful diagnostic marker for severe FXIII deficiency.

  7. When the C terminus of alpha(2)-antiplasmin was removed, the binding affinity for active site-blocked plasmin (show PLG Proteins) remained high, suggesting additional exosite interactions between the serpin core and plasmin (show PLG Proteins).

  8. Truncation of monocyte chemoattractant protein 1 (show CCL2 Proteins) by plasmin (show PLG Proteins) promotes blood-brain barrier disruption.

  9. ADAMTS13 (show ADAMTS13 Proteins) inactivation by plasmin (show PLG Proteins) as a potential cause of thrombotic thrombocytopenic purpura

  10. Results describe the functional characterization of the unique plasmin (show PLG Proteins)(ogen)-binding region of the human alpha(2)-plasmin inhibitor.

Rabbit Alpha2-Plasmin Inhititor (alpha2-PI) interaction partners

Alpha2-Plasmin Inhititor (alpha2-PI) Protein Profile

Protein Summary

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with alpha2-PI

  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (Serpinf2)
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2)
  • serine (or cysteine) peptidase inhibitor, clade F, member 2 (Serpinf2)
  • serine (or cysteine) peptidase inhibitor, clade F, member 2a (serpinf2a)
  • A2AP protein
  • AAP protein
  • AI747498 protein
  • ALPHA-2-PI protein
  • API protein
  • PLI protein
  • Serpimf2 protein
  • serpin protein
  • serpinf2 protein
  • serpinf2l protein
  • wu:fd57d08 protein

Protein level used designations for alpha2-PI

alpha 2 antiplasmin , alpha-2-AP , alpha-2-PI , alpha-2-antiplasmin , alpha-2-plasmin inhibitor , pigment epithelium derived factor , plasmin inhibitor alpha 2 , serine (or cysteine) proteinase inhibitor, clade F, member 2 , serpin F2 , serine (or cysteine) peptidase inhibitor, clade F, member 2 , serpin peptidase inhibitor, clade F , member 2, like , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 , alpha-2-PI serine protease inhibitor

GENE ID SPECIES
100717368 Cavia porcellus
611266 Canis lupus familiaris
18816 Mus musculus
560308 Danio rerio
5345 Homo sapiens
282522 Bos taurus
100009515 Oryctolagus cuniculus
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