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anti-Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (Human) (ASPSCR1) Antibodies

Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin.

list all antibodies Gene Name GeneID UniProt
ASPSCR1 68938 Q8VBT9
ASPSCR1    
ASPSCR1    
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Top anti-ASPSCR1 Antibodies at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Biotin IHC (p), WB 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p) 100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit HRP IHC (p), WB 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy5.5 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Cy7 IF (p) 100 μL Log in to see 14 to 21 Days
$379.50
Details

ASPSCR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human ,


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Rat (Rattus) ,


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More Antibodies against ASPSCR1 Interaction Partners

Mouse (Murine) Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (Human) (ASPSCR1) interaction partners

  1. Insulin (show INS Antibodies) acts through TUG proteins to control IRAP (show IL1RN Antibodies) targeting, similar to GLUT4 (show SLC2A4 Antibodies); the activity of vasopressin (show AVP Antibodies), an IRAP (show IL1RN Antibodies) substrate, is reduced in mice with disrupted TUG action in muscle.

  2. A conditional expression in mice of the fusion gene ASPSCR1-TFE3 (show TFE3 Antibodies) from human alveolar soft part sarcoma (ASPS (show DARS Antibodies)) generated a model that recapitulates the human tumor histologically and by expression profile.

  3. Data indicate that insulin (show INS Antibodies) stimulates proteolysis of TUG (tether containing a ubiquitin regulatory X (UBX) domain for glucose transporter 4 (GLUT4 (show SLC2A4 Antibodies))) to translocate GLUT4 (show SLC2A4 Antibodies) in muscle.

  4. Data suggest a model whereby insulin (show INS Antibodies) stimulates TUG cleavage to liberate GLUT4 (show SLC2A4 Antibodies) storage vesicles from the Golgi matrix, which promotes GLUT4 (show SLC2A4 Antibodies) translocation to the cell surface and enhances glucose uptake.

  5. TUG traps endocytosed GLUT4 (show SLC2A4 Antibodies) and tethers it intracellularly, and insulin (show INS Antibodies) mobilizes this pool of retained GLUT4 (show SLC2A4 Antibodies) by releasing this tether

  6. insulin (show INS Antibodies)-stimulated dissociation of TUG and GLUT4 (show SLC2A4 Antibodies) as an important action by which insulin (show INS Antibodies) stimulates glucose uptake.

ASPSCR1 Antigen Profile

Protein Summary

Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.

Gene names and symbols associated with ASPSCR1

  • alveolar soft part sarcoma chromosome region, candidate 1 (human) (Aspscr1) antibody
  • 1190006K01Rik antibody
  • ASPC antibody
  • ASPCR1 antibody
  • ASPL antibody
  • ASPS antibody
  • RCC17 antibody
  • TUG antibody

Protein level used designations for ASPSCR1

alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog , tether containing UBX domain for GLUT4 , tether, containing a UBX domain, for GLUT4

GENE ID SPECIES
68938 Mus musculus
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