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Amiloride-Sensitive Cation Channel 1, Neuronal Proteins (ACCN1)

The protein encoded by ACCN1 is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. Additionally we are shipping Amiloride-Sensitive Cation Channel 1, Neuronal Antibodies (34) and Amiloride-Sensitive Cation Channel 1, Neuronal Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACCN1 40 Q16515
ACCN1 11418 Q925H0
Rat ACCN1 ACCN1 25364 Q62962
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Top Amiloride-Sensitive Cation Channel 1, Neuronal Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ACCN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,
,

More Proteins for Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) Interaction Partners

Human Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) interaction partners

  1. Study shows that BNC1 expression was down-regulated in hepatocellular tumors and cell lines through its promotor hypermethylation.

  2. results demonstrate the occurrence of ASIC2 and TrkB (show NTRK2 Proteins) in the human intervertebral disc (IVD (show IVD Proteins)), and the increased expression of both in pathological IVD (show IVD Proteins) suggest their involvement in IVD (show IVD Proteins) degeneration

  3. distribution of ASIC2 in the human cutaneous mechanosensory system and suggest the involvement of ASIC2 in mechanosensation

  4. This study suggests that ASIC2 may play a role as mediators of inflammatory pain and be involved in the pathogenesis of frozen shoulder.

  5. Study demonstrates that Bnc1 regulates epithelial plasticity of mammary epithelial cells and influences outcome of TGF-beta1 (show TGFB1 Proteins) signaling.

  6. Combinatorial analysis suggests a model of random mixing of ASIC1a (show ACCN2 Proteins) and ASIC2a subunits to yield both 2:1 and 1:2 ASIC1a:ASIC2a heteromers together with ASIC1a (show ACCN2 Proteins) and ASIC2a homomers.

  7. p63 (show RPE65 Proteins) induces the expression of the basal epithelial transcription factor, Basonuclin 1 (show BNC1 Proteins).

  8. The results showed that there was a significant increase in the mean relative optical density of ASIC2 and ASIC3 (show ACCN3 Proteins) but not ASIC1a (show ACCN2 Proteins) in the lining epithelium and glandular tubes of gastric mucosa in patients with Henoch-Schonlein purpura.

  9. ACCN1 might be one of numerous susceptibility genes for panic disorder.

  10. these results indicate that ACCN1 gene is a potential candidate for response to lithium treatment that would serve as a genetic marker of lithium efficacy for bipolar disorder patients.

Mouse (Murine) Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) interaction partners

  1. differential surface trafficking of ASIC1a (show ACCN2 Proteins), ASIC2a, and ASIC2b, was investigated.

  2. These data identify the LL motifs as a negative regulator of ASIC2a trafficking and function, and suggest novel regulatory mechanisms in acid signaling.

  3. ASIC2 contributes to transduction of the renal myogenic response and has a protective role against renal injury and hypertension.

  4. These results lend support to an emerging role of ASIC2 in the targeting of ASICs to surface membranes, and allows for interaction with PSD-95 (show DLG4 Proteins) to regulate these processes.

  5. A previously unknown postsynaptic current during neurotransmission mediated by ASIC1A (show ACCN2 Proteins) and ASIC2 is well positioned to regulate synapse structure and function.

  6. ASIC2 knockout mice showed less sensitization to challenge cocaine when compared to wild-type.

  7. HSF2BP (show HSF2BP Proteins) may play a pivotal role in regulating BNC1 transcriptional activity and subcellular localization during spermatogenesis.

  8. Currents from ASIC1a (show ACCN2 Proteins)(-/-) muscle afferents were less pH-sensitive and displayed faster recovery, currents from ASIC2(-/-) showed diminished potentiation by zinc, and currents from ASIC3 (show ACCN3 Proteins)(-/-) displayed slower desensitization than those from wild-type.

  9. Anions modulate a variety of acid-sensing ion channel (show ACCN2 Proteins) properties and are dependent on subunit composition. The mechanism of modulation for ASIC2a and -3 is distinct from that of ASIC1a (show ACCN2 Proteins).

  10. BNC1 is required for the maintenance of spermatogenesis.

Zebrafish Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) interaction partners

  1. These results are the first demonstration that ASIC2 and ASIC4 (show ACCN4 Proteins) are expressed in the adult zebrafish retina

  2. The ASIC2 expression in this location might be related to detection of aquatic environment pH variations or to detection of water movement through the nasal cavity.

Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) Protein Profile

Protein Summary

The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. This gene seems to have multiple alternatively spliced transcript variants, but their full-length nature is not known yet. There seems to be evidence of multiple polyadenylation sites for this gene.

Gene names and symbols associated with ACCN1

  • acid-sensing (proton-gated) ion channel 2 (ASIC2)
  • acid-sensing (proton-gated) ion channel 2 (Asic2)
  • acid-sensing (proton-gated) ion channel 2 (asic2)
  • amiloride-sensitive cation channel 1, neuronal (ACCN1)
  • basonuclin 1 (BNC1)
  • basonuclin 1 (Bnc1)
  • ACCN protein
  • accn1 protein
  • ACIC2 protein
  • AI047752 protein
  • ASIC2a protein
  • AW546376 protein
  • BNaC1 protein
  • BNaC1a protein
  • Bnc protein
  • BNC1 protein
  • BNC1k protein
  • BSN1 protein
  • hBNaC1 protein
  • HsT19447 protein
  • Mdeg protein
  • MDEG1 protein
  • MDEG2 protein
  • zASIC2 protein

Protein level used designations for ACCN1

acid-sensing ion channel 2 , amiloride-sensitive cation channel 1, neuronal , brain sodium channel 1 , mammalian degenerin homolog , neuronal amiloride-sensitive cation channel 1 , amiloride-sensitive brain sodium channel , amiloride-sensitive cation channel 1, neuronal (degenerin) , degenerin , BNC1 , amiloride-sensitive brain sodium channel 2 , zinc finger protein basonuclin , zinc finger protein basonuclin-1

GENE ID SPECIES
40 Homo sapiens
11418 Mus musculus
25364 Rattus norvegicus
407669 Danio rerio
491150 Canis lupus familiaris
617930 Bos taurus
646 Homo sapiens
12173 Mus musculus
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