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anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) Antibodies

ACCN2 encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Additionally we are shipping Amiloride-Sensitive Cation Channel 2, Neuronal Kits (8) and Amiloride-Sensitive Cation Channel 2, Neuronal Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACCN2 79123 P55926
ACCN2 41 P78348
ACCN2 11419 Q6NXK8
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Top anti-Amiloride-Sensitive Cation Channel 2, Neuronal Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ACCN2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... Host: Rabbit  Target Name: ASIC1  Sample Tissue: MCF7 cell lysates  An... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ACCN2 Antibody (C-term) (ABIN653218) in CEM c... Formalin-fixed and paraffin-embedded human brain tissue reacted with A... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB ACCN2 Antibody (C-term) flow cytometric analysis of CEM cells (bottom ... Formalin-fixed and paraffin-embedded human brain tissue reacted with A... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Mouse Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Mouse Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Mouse Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Mouse Mouse PE ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Mouse Mouse Streptavidin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Mouse Mouse PerCP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

ACCN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Amiloride-Sensitive Cation Channel 2, Neuronal Antibodies

  1. Human Polyclonal ACCN2 Primary Antibody for EIA, FACS - ABIN950535 : Sherwood, Franke, Conneely, Joyner, Arumugan, Askwith: Identification of protein domains that control proton and calcium sensitivity of ASIC1a. in The Journal of biological chemistry 2009 (PubMed)
    Show all 3 references for ABIN950535

  2. Mouse (Murine) Monoclonal ACCN2 Primary Antibody for ICC, IF - ABIN2483697 : Garcuia-Aunoveros, Derfler, Neville-Golden, Hyman, Corey: BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 2 references for ABIN2483697

  3. Mouse (Murine) Monoclonal ACCN2 Primary Antibody for ICC, IF - ABIN2483698 : Wemmie, Coryell, Askwith, Lamani, Leonard, Sigmund, Welsh: Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 references for ABIN2483698

  4. Human Polyclonal ACCN2 Primary Antibody for FACS, IHC (p) - ABIN653218 : Kapoor, Bartoszewski, Qadri, Bebok, Bubien, Fuller, Benos: Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN653218

  5. Chicken Polyclonal ACCN2 Primary Antibody for WB - ABIN2776229 : Hettema, An, Neale, van den Oord, Kendler, Chen: Lack of association between the amiloride-sensitive cation channel 2 (ACCN2) gene and anxiety spectrum disorders. in Psychiatric genetics 2008 (PubMed)

More Antibodies against Amiloride-Sensitive Cation Channel 2, Neuronal Interaction Partners

Horse (Equine) Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) interaction partners

  1. Muscles from horses submitted to strenuous exercises produce lactic acid, which may induce variable pain through ACCN (show ACCN1 Antibodies) differential properties; ACCN1 and ACCN3 (show ACCN3 Antibodies) genes have an ubiquitous expression but ACCN1 is more highly expressed in the spinal cord.

Human Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) interaction partners

  1. analysis of a major ASIC1a homotetramer at the surface membrane of the cell expressing functional ASIC1a channel

  2. Our findings support previously reported associations between ASIC1 and panic/anxiety, but not other genes previously associated with anxiety disorders. The

  3. Putative GABAA (show GABRg1 Antibodies) and ASIC1a channels functionally interact with each other, possibly via an inter-molecular association by forming a novel protein complex.

  4. A novel interaction between ASIC1 and integrin-Beta1, mediated by alpha-actinin (show ACTN1 Antibodies) was determined in glioma tumor cells.

  5. ASIC1a opening is accompanied by a distance increase between adjacent thumb and palm domains as well as a movement of Glu (show DCTN1 Antibodies)-235 relative to the knuckle helix.

  6. ASIC1A and ENaCalpha (show SCNN1A Antibodies) form functional heterotrimers acting as ion channels.

  7. This study suggests that ASIC1 may play a role as mediators of inflammatory pain and be involved in the pathogenesis of frozen shoulder.

  8. Genetic variation at ACCN2 appears to be associated with panic disorder and with amygdala phenotypes that have been linked to proneness to anxiety.

  9. Down-regulated expression of ASIC1 RNA and protein was detected in the dysplastic cortex of focal cortical dysplasia patients.

  10. Provide evidence for the roles of OGR1 (show GPR68 Antibodies) and ASIC1a in the regulation of intestinal passive Mg(2 (show MUC7 Antibodies)+) absorption.

Mouse (Murine) Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) interaction partners

  1. This study demonstrated that asic1 proteins consist of distinct responsible for ion conduction, mechanical force sensing, and transduction to coordinately fulfill their function as sophisticated MS channels.

  2. Acid-sensing ion channel 1a drives AMPA (show GRIA3 Antibodies) receptor plasticity following ischaemia and acidosis in hippocampal CA1 (show CA1 Antibodies) neurons

  3. Deletion of the Asic1a gene significantly prevents RIP1 (show RALBP1 Antibodies) phosphorylation and brain damage, suggesting ASIC1a-mediated RIP1 (show RALBP1 Antibodies) activation has an important role in ischemic neuronal injury.

  4. Study suggests that ASIC1a activity facilitates NMDAR (show GRIN1 Antibodies) function and exacerbates NMDAR (show GRIN1 Antibodies)-mediated neuronal death in pathological conditions

  5. The data of this study suggest that ASIC1a may be a mediator of SCA1 (show ATXN1 Antibodies) pathogenesis and targeting ASIC1a could be a novel approach to treat SCA1 (show ATXN1 Antibodies).

  6. ASIC1A inhibits neuronal plasticity underlying addiction-related behavior; disrupting ASIC1A in the mouse nucleus accumbens increases cocaine-conditioned place preference.

  7. We conclude that this optogenetic method offers a minimally invasive approach that enables examining the biological consequences of ASIC1a currents in any structure of the CNS and in the modulation of animal behaviors.

  8. Data suggest that mitochondrial ASIC1a may serve as an important regulator of MPT pores, which contributes to oxidative neuronal cell death.

  9. Suggest that ASIC1a channels might be involved in controlling neuromuscular transmission, muscle contraction and fatigue in female mice.

  10. Mutations in binding motifs of ASIC1a reduce surface expression and pH sensitivity; C-terminal motifs are important for ASIC1a trafficking and channel function.

Pig (Porcine) Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) interaction partners

  1. Data from models of hyperactive bladder suggest that ASIC1 is involved in ATP release from bladder mucosa stimulated by stretch/acid; studies include evidence ASIC isoforms are expressed in lateral wall, dome, trigone, and neck of detrusor/mucosa.

Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) Antigen Profile

Protein Summary

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with ACCN2

  • amiloride-sensitive cation channel 2, neuronal (ACCN2) antibody
  • acid-sensing (proton-gated) ion channel 2 (ACCN1) antibody
  • Amiloride-sensitive cation channel 2, neuronal (accn2) antibody
  • acid-sensing (proton-gated) ion channel 1 (Asic1) antibody
  • acid-sensing (proton-gated) ion channel 1 (ASIC1) antibody
  • acid-sensing (proton-gated) ion channel 1 (ACCN2) antibody
  • ACCN2 antibody
  • AI843610 antibody
  • ASIC antibody
  • ASIC1 antibody
  • ASIC1a antibody
  • B530003N02Rik antibody
  • BNaC2 antibody

Protein level used designations for ACCN2

amiloride-sensitive cation channel 2, neuronal , amiloride-sensitive cation channel 1, neuronal , Amiloride-sensitive cation channel 2, neuronal , BNaC2 , acid-sensing ion channel 1 , brain sodium channel 2 , proton gated cation channel ASIC1 , Cation channel, amiloride-sensitive, neuronal, 2 , acid-sensing ion channel 1a protein , acid sensing ion channel , degenerin 2

GENE ID SPECIES
451888 Pan troglodytes
100058355 Equus caballus
100194955 Salmo salar
100355858 Oryctolagus cuniculus
713320 Macaca mulatta
79123 Rattus norvegicus
41 Homo sapiens
11419 Mus musculus
100517467 Sus scrofa
426883 Gallus gallus
477612 Canis lupus familiaris
538244 Bos taurus
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