anti-Amiloride-Sensitive Cation Channel 3 (ACCN3) Antibodies

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Additionally we are shipping Amiloride-Sensitive Cation Channel 3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACCN3 286920 O35240
ACCN3 9311 Q9UHC3
ACCN3 171209 Q6X1Y6
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Top anti-Amiloride-Sensitive Cation Channel 3 Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ACCN3  Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.2500  Positive Control: Human Kidney 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB Anti-ASIC3 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Rat Testis Tissue Lysate Lane 3: U87 Cell Lysate Lane 4: NEURO Cell Lysate Lane 5: SMMC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Cow Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated WB ACCN3 Antibody (N-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ACCN3 antibody detected the ACCN3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extract of various cells, using ASIC3 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC, WB ACCN3 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X ACCN3 antibody used at 2.5 ug/ml to detect target protein. 100 μg Log in to see 2 to 3 Days
$388.93
Details
Mouse Goat Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), WB   0.1 mL Log in to see 14 to 17 Days
$408.19
Details
Mouse Rabbit Un-conjugated IHC (p), IHC, WB Immunofluorescence: Amiloride-sensitive cation channel 3 Antibody [NBP1-20095] - Rat hypothalamus stained with anti-Amiloride-sensitive cation channel 3 antibody. Image from verified customer review. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details

ACCN3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,
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Human ,
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Mouse (Murine)
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Top referenced anti-Amiloride-Sensitive Cation Channel 3 Antibodies

  1. Cow (Bovine) Polyclonal ACCN3 Primary Antibody for IHC, WB - ABIN2776167 : Jones, Slater, Cadiou, McNaughton, McMahon: Acid-induced pain and its modulation in humans. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)

  2. Mouse (Murine) Polyclonal ACCN3 Primary Antibody for ICC, IF - ABIN4280263 : Durham, Masterson: Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment. in Headache 2013 (PubMed)

More Antibodies against Amiloride-Sensitive Cation Channel 3 Interaction Partners

Horse (Equine) Amiloride-Sensitive Cation Channel 3 (ACCN3) interaction partners

  1. Muscles from horses submitted to strenuous exercises produce lactic acid, which may induce variable pain through ACCN (show ACCN1 Antibodies) differential properties; ACCN1 (show ACCN2 Antibodies) and ACCN3 genes have an ubiquitous expression but ACCN1 (show ACCN2 Antibodies) is more highly expressed in the spinal cord.

Human Amiloride-Sensitive Cation Channel 3 (ACCN3) interaction partners

  1. The results show that acid-sensing ion channel 1 (show ACCN2 Antibodies), acid-sensing ion channel 2 (show ACCN1 Antibodies), and acid-sensing ion channel 3 are expressed in A549 cells at the messenger RNA and protein levels, and acid-sensing ion channel (show ACCN2 Antibodies)-like currents were elicited by extracellular acid stimuli.

  2. Blocking ASIC3 in interneurons from temporal lobe epilepsy patients decreased the frequency of action potential firing.

  3. These findings open new perspectives on the roles of ASIC3 in the absence of tissue pH variation, as well as on the contribution of those channels to lipid-mediated signaling.

  4. Sea (show Slc25a1 Antibodies) anemone peptide with uncommon beta-hairpin structure inhibits acid-sensing ion channel 3 (ASIC3) and reveals analgesic activity.

  5. Experiments with Asic3 inhibitors show that Asic3 inhibition leads to loss of pressure-induced vasodilation due to pressure detection failure rather than endothelial mechanisms.

  6. The highly proton sensitive ASIC3 channels are predominantly distributed in peripheral sensory neurons, correlating with their roles in multimodal sensory perception, including nociception, mechanosensation, and chemosensation.

  7. CAR and ASIC3 co-immunoprecipitate only when co-expressed with PSD-95 (show DLG4 Antibodies).

  8. Lignan from thyme possesses inhibitory effect on ASIC3 channel current.

  9. A mechanism of induction of ASIC-3 expression relevant to AR was suggested by the finding that eosinophil peroxidase (EPO (show EPX Antibodies)), acting via ERK1/2 (show MAPK1/3 Antibodies), induced the expression of ASIC-3 in epithelial cells.

  10. ASIC3 is able to sense the extracellular pH in both directions and to dynamically adapt its activity between pH 5.0 and 8.0, playing a role in fine tuning neuronal membrane potentials and neuron sensitization in various pH environments.

Mouse (Murine) Amiloride-Sensitive Cation Channel 3 (ACCN3) interaction partners

  1. High ASIC3 expression is associated with Bone Pain Induced by Multiple Myeloma.

  2. This study suggested that the macrophage- and neutrophil-produced IL1beta (show IL1B Antibodies) in the muscles during I/R activates enhanced IL1r1 (show IL1RN Antibodies) in muscle afferents increase expression of ASIC3 possibly via JNK (show MAPK8 Antibodies) activation.

  3. segmental analgesia of electroacupuncture-induced analgesia (EA) with lower intensity is partially mediated by ASIC3 receptor on Abeta (show APP Antibodies)-fiber, whereas systemic analgesia induced by EA with higher intensity is more likely induced by TRPV1 (show TRPV1 Antibodies) receptor on Adelta- and C-fibers

  4. the potentiation of ASICs by quinine depends on the presence of the ASIC1a (show ACCN2 Antibodies), ASIC2a (show ACCN1 Antibodies) subunits, but not ASIC1b, ASIC3 subunits. Furthermore, we have determined the amino acids in ASIC1a (show ACCN2 Antibodies) that are involved in the modulation of ASICs by pHi.

  5. fatigue reduces pH in muscle that subsequently activates ASIC3 on macrophages to enhance hyperalgesia to muscle insult.

  6. ASIC3 is critical for scratching behavior and pathological changes in chronic itch.

  7. Data suggest that activation of acid-sensing ion channel 3 (ASIC3) on fibroblast-like synoviocytes (FLS) by acidic pH from an inflamed joint could limit synovial proliferation resulting in reduced inflammatory mediators and subsequent joint damage.

  8. we unraveled an important role of ASIC3 in regulating cardiac autonomic function, whereby loss of ASIC3 alters the normal physiological response to ischemic stimuli.

  9. The activation of asic3 activity are essential for the development of long-lasting hyperalgesia in acid-induced, chronic, widespread muscle pain.

  10. Sea (show Slc25a1 Antibodies) anemone peptide with uncommon beta-hairpin structure inhibits acid-sensing ion channel 3 (ASIC3) and reveals analgesic activity.

Amiloride-Sensitive Cation Channel 3 (ACCN3) Antigen Profile

Protein Summary

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with ACCN3

  • amiloride-sensitive cation channel 3 (ACCN3) antibody
  • amiloride-sensitive cation channel 3 (LOC100350503) antibody
  • acid-sensing (proton-gated) ion channel 3 (Asic3) antibody
  • acid-sensing (proton-gated) ion channel 3 (ASIC3) antibody
  • Accn3 antibody
  • AW742291 antibody
  • DRASIC antibody
  • SLNAC1 antibody
  • TNAC1 antibody

Protein level used designations for ACCN3

amiloride-sensitive cation channel 3 , amiloride-sensitive cation channel 3-like , DRASIC , acid sensing ion channel 3 , acid-sensing ion channel 3 , dorsal root ASIC , proton gated cation channel DRASIC , amiloride-sensitive cation channel 3, testis , modulatory subunit of ASIC2a , neuronal amiloride-sensitive cation channel 3 , proton-gated cation channel subunit , testis sodium channel 1

GENE ID SPECIES
429486 Gallus gallus
100063408 Equus caballus
100350503 Oryctolagus cuniculus
100442058 Pongo abelii
286920 Rattus norvegicus
9311 Homo sapiens
171209 Mus musculus
482801 Canis lupus familiaris
789132 Bos taurus
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