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Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. Additionally we are shipping Amine Oxidase, Copper Containing 2 (Retina-Specific) Antibodies (20) and Amine Oxidase, Copper Containing 2 (Retina-Specific) Proteins (5) and many more products for this protein.
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AOC2 mRNA is expressed in many tissues, however, the only tissues with detectable AOC2-like enzyme activity is found in the eye.
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
, retina-specific copper amine oxidase
, semicarbazide-sensitive amine oxidase
, retina-specific amine oxidase
, amine oxidase, copper containing 2
, amine oxidase, copper containing 2 (retina-specific)
, amine oxidase, copper containing 3 (vascular adhesion protein 1)