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AOC3 encodes a member of the semicarbazide-sensitive amine oxidase family. Additionally we are shipping AOC3 Kits (16) and AOC3 Proteins (13) and many more products for this protein.
Showing 10 out of 93 products:
Mouse (Murine) Monoclonal AOC3 Primary Antibody for Func, IHC (fro) - ABIN1105387
Merinen, Irjala, Salmi, Jaakkola, Hänninen, Jalkanen: Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse. in The American journal of pathology 2005
Show all 6 references for ABIN1105387
Human Polyclonal AOC3 Primary Antibody for FACS, IHC (p) - ABIN652478
Lalor, Edwards, McNab, Salmi, Jalkanen, Adams: Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells. in Journal of immunology (Baltimore, Md. : 1950) 2002
Show all 2 references for ABIN652478
Human Monoclonal AOC3 Primary Antibody for Func, IHC (fro) - ABIN1105386
Martelius, Salaspuro, Salmi, Krogerus, Höckerstedt, Jalkanen, Lautenschlager: Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection. in The American journal of pathology 2004
Show all 2 references for ABIN1105386
Human Polyclonal AOC3 Primary Antibody for EIA, WB - ABIN453515
Salmi, Stolen, Jousilahti, Yegutkin, Tapanainen, Janatuinen, Knip, Jalkanen, Salomaa: Insulin-regulated increase of soluble vascular adhesion protein-1 in diabetes. in The American journal of pathology 2002
Show all 2 references for ABIN453515
Human Polyclonal AOC3 Primary Antibody for IHC (p), WB - ABIN522088
Hernandez-Guillamon, Solé, Delgado, García-Bonilla, Giralt, Boada, Penalba, García, Flores, Ribó, Alvarez-Sabin, Ortega-Aznar, Unzeta, Montaner: VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke. in Cerebrovascular diseases (Basel, Switzerland) 2012
Human Polyclonal AOC3 Primary Antibody for IHC, ELISA - ABIN190882
Forster-Horváth, Döme, Paku, Ladányi, Somlai, Jalkanen, Tímár: Loss of vascular adhesion protein-1 expression in intratumoral microvessels of human skin melanoma. in Melanoma research 2004
In this article, we will review the general characteristics and biological functions of VAP-1, focusing on its important role as a prognostic biomarker in human pathologies. [review]
serum VAP-1 can predict ESRD and is a useful biomarker to improve risk stratification in type 2 diabetic subjects.
Higher serum VAP-1 and Chronic kidney disease can independently predict future development of cancers in type II diabetic subjects
Complexes of human ORP2 and VAPs at endoplasmic reticulum-lipid droplet interfaces regulate the hydrolysis of triglycerides and lipid droplet turnover.
these results link the amine oxidase (show MAOA Antibodies) activity of VAP-1 with hepatic inflammation and fibrosis and suggest that targeting VAP-1 has therapeutic potential for NAFLD (show TSC2 Antibodies) and other chronic fibrotic liver diseases.
the semicarbazide-sensitive amine oxidase (show AOC2 Antibodies) activity of VAP-1 modifies hepatic glucose homeostasis and may contribute to patterns of GLUT (show SLC2A1 Antibodies) expression in chronic disease.
This study demonstrated that low serum VAP-1 levels are associated with poor prognosis in gastric cancer patients.
Serum VAP-1 predicts mortality independently and improves risk stratification in colorectal cancer subjects.
SSAO (show AOC2 Antibodies) expression in endothelial cells increases oxygen-glucose-deprivation-associated cell damage. It mediates some tissue damage during the reoxygenation process by oxidizing its known enzymatic substrate, methylamine.
We concluded that VAP-1, elevated in patients on Peritoneal Dialysis, was predominantly dependent on residual kidney function and glucose level, factors both linked to endothelial damage and cardiovascular complications.
data indicate that SSAO inactivation in vivo stabilizes the established plaques mainly via inducing the switch of SMCs from a contractile to a synthetic phenotype
Suggest inhibiting VAP-1/SSAO enzymatic function, by PXS-4728A, as a novel therapeutic approach in lung diseases that are characterized by neutrophilic pattern of inflammation.
these results suggest a largely redundant function for AOC3/VAP-1 in allergic inflammatory responses of the airways.
The results of the study establish VCAM-1 (show VCAM1 Antibodies) and VAP-1 as mediators of myeloid cell recruitment in metastasis and identify VAP-1 as a potential target for therapeutic intervention to combat early metastasis.
The antihyperglycemic effect of benzylamine is abolished by AOC3 gene knockout in mice.
Long-term activation of semicarbazide-sensitive amine oxidase by benzylamine lowers circulating levels of uric acid in diabetic conditions.
AOC3 expression is increased in perigonadal and subcutaneous adipose tissue of diabetic db-/- obese mice.
This review examines the biological functions of VAP-1, especially the role that this molecule might play in the establishment and progression of chronic liver disease.
The demonstrated AOC3 turnover of primary amines that are non-native to human tissue suggests possible roles for the adipocyte enzyme in subcutaneous bacterial infiltration and obesity.
The lysine-rich protein soluble elastin (show ELN Antibodies) bound to the enzyme tightly, which may have relevance to the reported roles of copper-containing quinoenzyme semicarbazide-sensitive amine oxidase in maintaining the extracellular matrix and in maturation of elastin (show ELN Antibodies)
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
, SEC31-like protein 1
, SEC31-related protein A
, protein transport protein Sec31A
, vesicle associated protein
, vesicle-associated protein 1
, amine oxidase, copper containing 3 (vascular adhesion protein 1)
, copper amine oxidase
, membrane primary amine oxidase
, placenta copper monamine oxidase
, semicarbazide-sensitive amine oxidase
, vascular adhesion protein 1
, copper containing amine oxidase 3
, primary amine oxidase, lung isozyme