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The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. Additionally we are shipping AIMP2 Proteins (7) and many more products for this protein.
Showing 10 out of 53 products:
Human Polyclonal AIMP2 Primary Antibody for EIA, WB - ABIN358043
Nicolaides, Kinzler, Vogelstein: Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. in Genomics 1996
Show all 2 references for ABIN358043
Human Polyclonal AIMP2 Primary Antibody for WB - ABIN389383
Kim, Park, Kang, Kim, Park, Kang, Lee, Han, Lee, Kim: Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation. in Nature genetics 2003
Show all 2 references for ABIN389383
analysis of the heterotetrameric complex structure of the glutathione transferase (GST (show SLCO6A1 Antibodies)) domains shared among the four MSC (show MSC Antibodies) components, methionyl-tRNA synthetase (show MARS Antibodies) (MRS), glutaminyl-prolyl-tRNA synthetase (EPRS (show EPRS Antibodies)), AIMP2 and AIMP3 (show EEF1E1 Antibodies)
Ubiquitin and SUMO compete for the same lysine (K242) on influenza A virus M1 and the interaction of viral NS2 with human AIMP2 facilitates the switch of the M1 modification from ubiquitination to SUMOylation, thus increasing viral replication.
These findings suggested that, although excessive accumulation of oxidative DNA damage was present in LSCs, the relatively decreased phosphorylation of p38 (show CRK Antibodies) might help leukemic cells escape senescence and apoptosis.
Transgeneic overexpression of AIMP2 led to a selective, age-dependent, progressive loss of dopaminergic neurons.
The tumorigenic activity of AIMP2-DX2 can be controlled by the small chemical BC-DXI01, which can selectively suppress the AIMP2-DX2 mRNA transcript.
AIMP2-DX2, a splicing variant of tumor suppressor AIMP2, can be a therapeutic target to control chemoresistant epithelial ovarian cancer .
downregulation of AIMP2 lacking exon 2 (AIMP2-DX2), expressed in different cancer cells, suppressed the epidermal growth factor receptor (show EGFR Antibodies)/mitogen activated protein kinase (show MAPK1 Antibodies) signaling pathway
ribozyme could selectively deliver the activity of a suicide gene into the AIMP2-DX2 RNA expressing lung cancer cells and thereby specifically and effectively retard the growth of the cancer cells with prodrug treatment.
a splicing variant of AIMP2 lacking exon 2 (AIMP2-DX2) is highly expressed by alternative splicing in human lung cancer cells and patient's tissues
functional significance of AIMP2 in determination of cell proliferation and death, and as a haploinsufficient tumor suppressor.
The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown.
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
, aminoacyl tRNA synthase complex-interacting multifunctional protein 2
, ARS-interacting multi-functional protein 2
, multisynthase complex auxiliary component p38
, multisynthetase complex auxiliary component p38
, protein JTV-1
, ARS interacting multifunctional protein 2