Aminoadipate Semialdehyde Synthase Proteins (AASS)

AASS encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. Additionally we are shipping Aminoadipate Semialdehyde Synthase Antibodies (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AASS 10157 Q9UDR5
AASS 30956 Q99K67
Rat AASS AASS 296925 A2VCW9
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Top Aminoadipate Semialdehyde Synthase Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$672.00
Details
Escherichia coli (E. coli) Mouse T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$696.00
Details

AASS Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,

More Proteins for Aminoadipate Semialdehyde Synthase (AASS) Interaction Partners

Human Aminoadipate Semialdehyde Synthase (AASS) interaction partners

  1. GR and KLF15 physically interact via low affinity GR binding sites within glucocorticoid response elements (GREs) for PRODH and AASS that contribute to combinatorial regulation with KLF15.

  2. Mitochondrial NADPH (show NQO1 Proteins) is crucial for AASS function

  3. Hyperlysinemia is caused by mutations in AASS

Mouse (Murine) Aminoadipate Semialdehyde Synthase (AASS) interaction partners

  1. These results indicate AASS knockdown decreases the lysine requirement of the cell via a reduction of lysine catabolism through the saccharopine pathway.

  2. Mice receiving the high-protein diet had greater AASS mRNA compared to mice fed the adequate protein diet.

Aminoadipate Semialdehyde Synthase (AASS) Protein Profile

Protein Summary

This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

Gene names and symbols associated with AASS

  • aminoadipate-semialdehyde synthase (AASS)
  • aminoadipate-semialdehyde synthase (Aass)
  • LKR protein
  • LKR/SDH protein
  • LKRSDH protein
  • LOR protein
  • LOR/SDH protein
  • Lorsdh protein
  • SDH protein

Protein level used designations for AASS

alpha-aminoadipate semialdehyde synthase , alpha-aminoadipic semialdehyde synthase, mitochondrial , aminoadipic semialdehyde synthase , lysine-2-oxoglutarate reductase , lysine-ketoglutarate reductase /saccharopine dehydrogenase , lysine oxoglutarate reductase , saccharopine dehydrogenase , LKR/SDH

GENE ID SPECIES
10157 Homo sapiens
30956 Mus musculus
296925 Rattus norvegicus
520865 Bos taurus
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