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Aminocarboxymuconate Semialdehyde Decarboxylase Proteins (ACMSD)

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Additionally we are shipping ACMSD Antibodies (19) and ACMSD Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACMSD 266645 Q8R519
ACMSD 130013 Q8TDX5
ACMSD 171385 Q8R5M5
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Top ACMSD Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,293.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,907.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,907.67
Details
Yeast Caenorhabditis elegans His tag   1 mg Log in to see 56 to 66 Days
$3,111.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ACMSD Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) Interaction Partners

Mouse (Murine) Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) interaction partners

  1. Acmsd gene expression was found to be under the control of both hepatocyte nuclear factor 4alpha (HNF4alpha (show HNF4A Proteins)) and peroxisome proliferator-activated receptor alpha (PPARalpha (show PPARA Proteins)).

Human Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD) interaction partners

  1. ACMSD is mutated in a family with cortical myoclonus, epilepsy, and parkinsonism. ACMSD mutation contributes to the development of Familial cortical myoclonic tremor and epilepsy.

  2. Data report a crystal structure of human ACMSD in complex with the glycolytic intermediate 1,3-dihydroxyacetonephosphate (DHAP (show ALDH3A2 Proteins)),suggesting a regulatory link between NAD synthesis and glycolysis.

ACMSD Protein Profile

Protein Summary

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase\; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Gene names and symbols associated with ACMSD

  • aminocarboxymuconate semialdehyde decarboxylase (ACMSD)
  • aminocarboxymuconate semialdehyde decarboxylase (acmsd)
  • 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase-like (LOC100154768)
  • amino carboxymuconate semialdehyde decarboxylase (Acmsd)
  • aminocarboxymuconate semialdehyde decarboxylase (Acmsd)
  • ACMSD protein
  • zgc:162888 protein

Protein level used designations for ACMSD

aminocarboxymuconate semialdehyde decarboxylase , 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase , 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase , 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase-like , picolinate carboxylase

GENE ID SPECIES
424288 Gallus gallus
557166 Danio rerio
733325 Xenopus laevis
459627 Pan troglodytes
476125 Canis lupus familiaris
708917 Macaca mulatta
100413800 Callithrix jacchus
100446661 Pongo abelii
100483355 Ailuropoda melanoleuca
100528249 Ictalurus punctatus
100154768 Sus scrofa
266645 Mus musculus
130013 Homo sapiens
171385 Rattus norvegicus
515030 Bos taurus
Selected quality suppliers for ACMSD Proteins (ACMSD)
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